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Items: 1 to 20 of 49

1.

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.

Cui G, Hong J, Chung-Davidson YW, Infield D, Xu X, Li J, Simhaev L, Khazanov N, Stauffer B, Imhoff B, Cottrill K, Blalock JE, Li W, Senderowitz H, Sorscher E, McCarty NA, Gaggar A.

Dev Cell. 2019 Nov 18;51(4):421-430.e3. doi: 10.1016/j.devcel.2019.09.017. Epub 2019 Oct 31.

PMID:
31679858
2.

Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics.

Zang X, Monge ME, Gaul DA, McCarty NA, Stecenko A, Fernández FM.

J Proteome Res. 2020 Jan 3;19(1):144-152. doi: 10.1021/acs.jproteome.9b00443. Epub 2019 Oct 30.

PMID:
31621328
3.

VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level.

Cui G, Stauffer BB, Imhoff BR, Rab A, Hong JS, Sorscher EJ, McCarty NA.

Sci Rep. 2019 Sep 17;9(1):13460. doi: 10.1038/s41598-019-49921-4.

4.

ATP-Dependent Signaling in Simulations of a Revised Model of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Strickland KM, Stock G, Cui G, Hwang H, Infield DT, Schmidt-Krey I, McCarty NA, Gumbart JC.

J Phys Chem B. 2019 Apr 18;123(15):3177-3188. doi: 10.1021/acs.jpcb.8b11970. Epub 2019 Apr 10.

PMID:
30921517
5.

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections.

Agarwal R, Johnson CT, Imhoff BR, Donlan RM, McCarty NA, García AJ.

Nat Biomed Eng. 2018 Nov;2(11):841-849. doi: 10.1038/s41551-018-0263-5. Epub 2018 Jul 16. No abstract available.

6.

Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development.

Mojib N, Xu J, Bartolek Z, Imhoff B, McCarty NA, Shin CH, Kubanek J.

Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3.

7.

Correction: The "new normal": Adapting doctoral trainee career preparation for broad career paths in science.

St Clair R, Hutto T, MacBeth C, Newstetter W, McCarty NA, Melkers J.

PLoS One. 2017 Jul 7;12(7):e0181294. doi: 10.1371/journal.pone.0181294. eCollection 2017.

8.

Molecular Dynamics Flexible Fitting Simulations Identify New Models of the Closed State of the Cystic Fibrosis Transmembrane Conductance Regulator Protein.

Simhaev L, McCarty NA, Ford RC, Senderowitz H.

J Chem Inf Model. 2017 Aug 28;57(8):1932-1946. doi: 10.1021/acs.jcim.7b00091. Epub 2017 Jul 18.

PMID:
28657312
9.

The "new normal": Adapting doctoral trainee career preparation for broad career paths in science.

St Clair R, Hutto T, MacBeth C, Newstetter W, McCarty NA, Melkers J.

PLoS One. 2017 May 24;12(5):e0177035. doi: 10.1371/journal.pone.0177035. eCollection 2017. Erratum in: PLoS One. 2017 Jul 7;12 (7):e0181294.

10.

Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics.

Zang X, Pérez JJ, Jones CM, Monge ME, McCarty NA, Stecenko AA, Fernández FM.

J Am Soc Mass Spectrom. 2017 Aug;28(8):1489-1496. doi: 10.1007/s13361-017-1660-9. Epub 2017 Mar 31.

PMID:
28364225
11.

Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner.

Molina SA, Moriarty HK, Infield DT, Imhoff BR, Vance RJ, Kim AH, Hansen JM, Hunt WR, Koval M, McCarty NA.

Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L688-L702. doi: 10.1152/ajplung.00364.2016. Epub 2017 Feb 17.

12.

Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study.

Zang X, Monge ME, McCarty NA, Stecenko AA, Fernández FM.

J Proteome Res. 2017 Feb 3;16(2):550-558. doi: 10.1021/acs.jproteome.6b00675. Epub 2016 Dec 2.

PMID:
28152602
13.

Ability of device to collect bacteria from cough aerosols generated by adults with cystic fibrosis.

Ku DN, Ku SK, Helfman B, McCarty NA, Wolff BJ, Winchell JM, Anderson LJ.

F1000Res. 2016 Aug 5;5:1920. eCollection 2016.

14.

Potentiators exert distinct effects on human, murine, and Xenopus CFTR.

Cui G, Khazanov N, Stauffer BB, Infield DT, Imhoff BR, Senderowitz H, McCarty NA.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207. doi: 10.1152/ajplung.00056.2016. Epub 2016 Jun 10.

15.

Advanced glycation end products are elevated in cystic fibrosis-related diabetes and correlate with worse lung function.

Hunt WR, Helfman BR, McCarty NA, Hansen JM.

J Cyst Fibros. 2016 Sep;15(5):681-8. doi: 10.1016/j.jcf.2015.12.011. Epub 2016 Jan 23.

16.

Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator.

Infield DT, Cui G, Kuang C, McCarty NA.

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 1;310(5):L403-14. doi: 10.1152/ajplung.00259.2015. Epub 2015 Dec 18.

17.

A longitudinal analysis of chronic MRSA and Pseudomonas aeruginosa co-infection in cystic fibrosis: A single-center study.

Maliniak ML, Stecenko AA, McCarty NA.

J Cyst Fibros. 2016 May;15(3):350-6. doi: 10.1016/j.jcf.2015.10.014. Epub 2015 Nov 21.

18.

Murine and human CFTR exhibit different sensitivities to CFTR potentiators.

Cui G, McCarty NA.

Am J Physiol Lung Cell Mol Physiol. 2015 Oct 1;309(7):L687-99. doi: 10.1152/ajplung.00181.2015. Epub 2015 Jul 24.

19.

Junctional abnormalities in human airway epithelial cells expressing F508del CFTR.

Molina SA, Stauffer B, Moriarty HK, Kim AH, McCarty NA, Koval M.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 1;309(5):L475-87. doi: 10.1152/ajplung.00060.2015. Epub 2015 Jun 26.

20.

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.

Cui G, Rahman KS, Infield DT, Kuang C, Prince CZ, McCarty NA.

J Gen Physiol. 2014 Aug;144(2):159-79. doi: 10.1085/jgp.201311122. Epub 2014 Jul 14.

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