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Items: 1 to 20 of 46


Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer.

Chen KY, Santos Afonso ED, Enouf V, Isel C, Naffakh N.

PLoS Pathog. 2019 Oct 3;15(10):e1008034. doi: 10.1371/journal.ppat.1008034. eCollection 2019 Oct.


Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.

Ashraf U, Tengo L, Le Corre L, Fournier G, Busca P, McCarthy AA, Rameix-Welti MA, Gravier-Pelletier C, Ruigrok RWH, Jacob Y, Vidalain PO, Pietrancosta N, Crépin T, Naffakh N.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10968-10977. doi: 10.1073/pnas.1901214116. Epub 2019 May 10.


Advances in Analyzing Virus-Induced Alterations of Host Cell Splicing.

Ashraf U, Benoit-Pilven C, Lacroix V, Navratil V, Naffakh N.

Trends Microbiol. 2019 Mar;27(3):268-281. doi: 10.1016/j.tim.2018.11.004. Epub 2018 Dec 19. Review.


Metal-Tagging Transmission Electron Microscopy and Immunogold Labeling on Tokuyasu Cryosections to Image Influenza A Virus Ribonucleoprotein Transport and Packaging.

Sachse M, de Castro IF, Fournier G, Naffakh N, Risco C.

Methods Mol Biol. 2018;1836:281-301. doi: 10.1007/978-1-4939-8678-1_14.


Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009.

Pagani I, Di Pietro A, Oteiza A, Ghitti M, Mechti N, Naffakh N, Vicenzi E.

mSphere. 2018 Apr 4;3(2). pii: e00110-18. doi: 10.1128/mSphere.00110-18. Print 2018 Apr 25.


Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans.

Biquand E, Poirson J, Karim M, Declercq M, Malausse N, Cassonnet P, Barbezange C, Straub ML, Jones L, Munier S, Naffakh N, van der Werf S, Jacob Y, Masson M, Demeret C.

mSphere. 2017 Nov 22;2(6). pii: e00330-17. doi: 10.1128/mSphere.00330-17. eCollection 2017 Nov-Dec.


Influenza virus genome reaches the plasma membrane via a modified endoplasmic reticulum and Rab11-dependent vesicles.

de Castro Martin IF, Fournier G, Sachse M, Pizarro-Cerda J, Risco C, Naffakh N.

Nat Commun. 2017 Nov 9;8(1):1396. doi: 10.1038/s41467-017-01557-6.


Structural basis of an essential interaction between influenza polymerase and Pol II CTD.

Lukarska M, Fournier G, Pflug A, Resa-Infante P, Reich S, Naffakh N, Cusack S.

Nature. 2017 Jan 5;541(7635):117-121. doi: 10.1038/nature20594. Epub 2016 Dec 21.


Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.

Quach H, Rotival M, Pothlichet J, Loh YE, Dannemann M, Zidane N, Laval G, Patin E, Harmant C, Lopez M, Deschamps M, Naffakh N, Duffy D, Coen A, Leroux-Roels G, Clément F, Boland A, Deleuze JF, Kelso J, Albert ML, Quintana-Murci L.

Cell. 2016 Oct 20;167(3):643-656.e17. doi: 10.1016/j.cell.2016.09.024.


Influenza A Virus Polymerase Recruits the RNA Helicase DDX19 to Promote the Nuclear Export of Viral mRNAs.

Diot C, Fournier G, Dos Santos M, Magnus J, Komarova A, van der Werf S, Munier S, Naffakh N.

Sci Rep. 2016 Sep 22;6:33763. doi: 10.1038/srep33763.


Experimental Approaches to Study Genome Packaging of Influenza A Viruses.

Isel C, Munier S, Naffakh N.

Viruses. 2016 Aug 9;8(8). pii: E218. doi: 10.3390/v8080218. Review.


Time-Resolved Visualisation of Nearly-Native Influenza A Virus Progeny Ribonucleoproteins and Their Individual Components in Live Infected Cells.

Avilov S, Magnus J, Cusack S, Naffakh N.

PLoS One. 2016 Mar 15;11(3):e0149986. doi: 10.1371/journal.pone.0149986. eCollection 2016.


Targeting host calpain proteases decreases influenza A virus infection.

Blanc F, Furio L, Moisy D, Yen HL, Chignard M, Letavernier E, Naffakh N, Mok CK, Si-Tahar M.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L689-99. doi: 10.1152/ajplung.00314.2015. Epub 2016 Jan 8.


Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation.

Da Costa B, Sausset A, Munier S, Ghounaris A, Naffakh N, Le Goffic R, Delmas B.

J Virol. 2015 Jun;89(12):6376-90. doi: 10.1128/JVI.00589-15. Epub 2015 Apr 8.


Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing.

Fournier G, Chiang C, Munier S, Tomoiu A, Demeret C, Vidalain PO, Jacob Y, Naffakh N.

PLoS Pathog. 2014 Jun 12;10(6):e1004164. doi: 10.1371/journal.ppat.1004164. eCollection 2014 Jun. Erratum in: PLoS Pathog. 2014 Jul;10(7):e1004317.


Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens.

Trapp S, Soubieux D, Marty H, Esnault E, Hoffmann TW, Chandenier M, Lion A, Kut E, Quéré P, Larcher T, Ledevin M, Munier S, Naffakh N, Marc D.

J Gen Virol. 2014 Jun;95(Pt 6):1233-43. doi: 10.1099/vir.0.063776-0. Epub 2014 Apr 2.


Multiple hosts and Influenza A viruses genetic mixing.

Rivailler P, Moisy D, Naffakh N.

Virologie (Montrouge). 2013 Dec 1;17(6):387-400. doi: 10.1684/vir.2013.0540.


Productive infection of human skeletal muscle cells by pandemic and seasonal influenza A(H1N1) viruses.

Desdouits M, Munier S, Prevost MC, Jeannin P, Butler-Browne G, Ozden S, Gessain A, Van Der Werf S, Naffakh N, Ceccaldi PE.

PLoS One. 2013 Nov 5;8(11):e79628. doi: 10.1371/journal.pone.0079628. eCollection 2013.


CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.

Berre S, Gaudin R, Cunha de Alencar B, Desdouits M, Chabaud M, Naffakh N, Rabaza-Gairi M, Gobert FX, Jouve M, Benaroch P.

J Exp Med. 2013 Nov 18;210(12):2523-38. doi: 10.1084/jem.20130566. Epub 2013 Oct 21.


Interactions moléculaires entre les ribonucléoprotéines des virus influenza de type A et la cellule hôte.

Moisy D, Naffakh N.

Virologie (Montrouge). 2013 Aug 1;17(4):278-293. doi: 10.1684/vir.2013.0510.


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