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Items: 1 to 20 of 32

1.

Design and synthesis of fluorogenic substrate-based probes for detecting Cathepsin B activity.

Wang S, Vigliarolo BG, Chowdhury MA, Nyarko JNK, Mousseau DD, Phenix CP.

Bioorg Chem. 2019 Aug 14;92:103194. doi: 10.1016/j.bioorg.2019.103194. [Epub ahead of print]

PMID:
31493706
2.

Enhancing Predictive Accuracy of Cardiac Autonomic Neuropathy Using Blood Biochemistry Features and Iterative Multitier Ensembles.

Abawajy J, Kelarev A, Chowdhury MU, Jelinek HF.

IEEE J Biomed Health Inform. 2016 Jan;20(1):408-15. doi: 10.1109/JBHI.2014.2363177. Epub 2014 Oct 20.

PMID:
25347890
3.

Creating and virtually screening databases of fluorescently-labelled compounds for the discovery of target-specific molecular probes.

Kamstra RL, Dadgar S, Wigg J, Chowdhury MA, Phenix CP, Floriano WB.

J Comput Aided Mol Des. 2014 Nov;28(11):1129-42. doi: 10.1007/s10822-014-9789-0. Epub 2014 Aug 24.

PMID:
25150502
4.

Suppression of network activity in dorsal horn by gabapentin permeation of TRPV1 channels: implications for drug access to cytoplasmic targets.

Biggs JE, Stemkowski PL, Knaus EE, Chowdhury MA, Ballanyi K, Smith PA.

Neurosci Lett. 2015 Jan 1;584:397-402. doi: 10.1016/j.neulet.2014.07.033. Epub 2014 Jul 29.

PMID:
25079903
5.

Prodrug-inspired probes selective to cathepsin B over other cysteine cathepsins.

Chowdhury MA, Moya IA, Bhilocha S, McMillan CC, Vigliarolo BG, Zehbe I, Phenix CP.

J Med Chem. 2014 Jul 24;57(14):6092-104. doi: 10.1021/jm500544p. Epub 2014 Jul 3.

PMID:
24940640
6.

Predicting cardiac autonomic neuropathy category for diabetic data with missing values.

Abawajy J, Kelarev A, Chowdhury M, Stranieri A, Jelinek HF.

Comput Biol Med. 2013 Oct;43(10):1328-33. doi: 10.1016/j.compbiomed.2013.07.002. Epub 2013 Jul 12.

PMID:
24034723
7.

An approach for Ewing test selection to support the clinical assessment of cardiac autonomic neuropathy.

Stranieri A, Abawajy J, Kelarev A, Huda S, Chowdhury M, Jelinek HF.

Artif Intell Med. 2013 Jul;58(3):185-93. doi: 10.1016/j.artmed.2013.04.007. Epub 2013 Jun 13.

PMID:
23768975
8.

Disability among elderly rural villagers: report of a survey from Gonoshasthaya Kendra, Bangladesh.

Cherry N, Chowdhury M, Haque R, McDonald C, Chowdhury Z.

BMC Public Health. 2012 May 25;12:379. doi: 10.1186/1471-2458-12-379.

9.

A diazen-1-ium-1,2-diolated nitric oxide donor ester prodrug of 3-(4-hydroxymethylphenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one: synthesis, biological evaluation and nitric oxide release studies.

Abdellatif KR, Huang Z, Chowdhury MA, Kaufman S, Knaus EE.

Bioorg Med Chem Lett. 2011 Jul 1;21(13):3951-6. doi: 10.1016/j.bmcl.2011.05.017. Epub 2011 May 14.

PMID:
21641217
10.

Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.

Huang Z, Velázquez CA, Abdellatif KR, Chowdhury MA, Reisz JA, DuMond JF, King SB, Knaus EE.

J Med Chem. 2011 Mar 10;54(5):1356-64. doi: 10.1021/jm101403g. Epub 2011 Jan 31.

PMID:
21280601
11.

Triaryl (Z)-olefins suitable for radiolabeling with iodine-124 or fluorine-18 radionuclides for positron emission tomography imaging of estrogen positive breast tumors.

Abdellatif KR, Velázquez CA, Huang Z, Chowdhury MA, Knaus EE.

Bioorg Med Chem Lett. 2011 Feb 15;21(4):1195-8. doi: 10.1016/j.bmcl.2010.12.091. Epub 2010 Dec 23.

PMID:
21237640
12.

Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.

Chowdhury MA, Huang Z, Abdellatif KR, Dong Y, Yu G, Velázquez CA, Knaus EE.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5776-80. doi: 10.1016/j.bmcl.2010.07.132. Epub 2010 Aug 3.

PMID:
20727750
13.

Acyclic triaryl olefins possessing a sulfohydroxamic acid pharmacophore: synthesis, nitric oxide/nitroxyl release, cyclooxygenase inhibition, and anti-inflammatory studies.

Huang Z, Velázquez C, Abdellatif K, Chowdhury M, Jain S, Reisz J, Dumond J, King SB, Knaus E.

Org Biomol Chem. 2010 Sep 21;8(18):4124-30. doi: 10.1039/c005066k. Epub 2010 Jul 22.

PMID:
20664853
14.

Triaryl (Z)-olefins suitable for radiolabeling with carbon-11 or fluorine-18 radionuclides for positron emission tomography imaging of cyclooxygenase-2 expression in pathological disease.

Abdellatif KR, Velázquez CA, Huang Z, Chowdhury MA, Knaus EE.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):5245-50. doi: 10.1016/j.bmcl.2010.06.155. Epub 2010 Jul 23.

PMID:
20655211
15.

Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.

Abdellatif KR, Chowdhury MA, Velázquez CA, Huang Z, Dong Y, Das D, Yu G, Suresh MR, Knaus EE.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4544-9. doi: 10.1016/j.bmcl.2010.06.022. Epub 2010 Jun 8.

PMID:
20576432
16.

Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.

Yu G, Praveen Rao PN, Chowdhury MA, Abdellatif KR, Dong Y, Das D, Velázquez CA, Suresh MR, Knaus EE.

Bioorg Med Chem Lett. 2010 Apr 1;20(7):2168-73. doi: 10.1016/j.bmcl.2010.02.040. Epub 2010 Feb 13.

PMID:
20202839
17.

Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.

Chowdhury MA, Abdellatif KR, Dong Y, Yu G, Huang Z, Rahman M, Das D, Velázquez CA, Suresh MR, Knaus EE.

Bioorg Med Chem Lett. 2010 Feb 15;20(4):1324-9. doi: 10.1016/j.bmcl.2010.01.014. Epub 2010 Jan 11.

PMID:
20097072
18.

Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.

Yu G, Chowdhury MA, Abdellatif KR, Dong Y, Praveen Rao PN, Das D, Velázquez CA, Suresh MR, Knaus EE.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):896-902. doi: 10.1016/j.bmcl.2009.12.073. Epub 2009 Dec 23.

PMID:
20045320
19.

Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.

Chowdhury MA, Abdellatif KR, Dong Y, Das D, Yu G, Velázquez CA, Suresh MR, Knaus EE.

Bioorg Med Chem Lett. 2009 Dec 15;19(24):6855-61. doi: 10.1016/j.bmcl.2009.10.083. Epub 2009 Oct 23.

PMID:
19884005
20.

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.

Abdellatif KR, Chowdhury MA, Dong Y, Das D, Yu G, Velázquez C, Suresh MR, Knaus EE.

Bioorg Med Chem. 2009 Jul 15;17(14):5182-8. doi: 10.1016/j.bmc.2009.05.046. Epub 2009 May 27.

PMID:
19500994

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