Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 45


Deiodinases and their intricate role in thyroid hormone homeostasis.

Luongo C, Dentice M, Salvatore D.

Nat Rev Endocrinol. 2019 Aug;15(8):479-488. doi: 10.1038/s41574-019-0218-2. Review.


The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress.

Sagliocchi S, Cicatiello AG, Di Cicco E, Ambrosio R, Miro C, Di Girolamo D, Nappi A, Mancino G, De Stefano MA, Luongo C, Raia M, Ogawa-Wong AN, Zavacki AM, Paladino S, Salvatore D, Dentice M.

Redox Biol. 2019 Jun;24:101228. doi: 10.1016/j.redox.2019.101228. Epub 2019 May 22.


Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats.

Nettore IC, Rocca C, Mancino G, Albano L, Amelio D, Grande F, Puoci F, Pasqua T, Desiderio S, Mazza R, Terracciano D, Colao A, Bèguinot F, Russo GL, Dentice M, Macchia PE, Sinicropi MS, Angelone T, Ungaro P.

J Nutr Biochem. 2019 Jul;69:151-162. doi: 10.1016/j.jnutbio.2019.03.019. Epub 2019 Apr 8.


A Global Loss of Dio2 Leads to Unexpected Changes in Function and Fiber Types of Slow Skeletal Muscle in Male Mice.

Carmody C, Ogawa-Wong AN, Martin C, Luongo C, Zuidwijk M, Sager B, Petersen T, Roginski Guetter A, Janssen R, Wu EY, Bogaards S, Neumann NM, Hau K, Marsili A, Boelen A, Silva JE, Dentice M, Salvatore D, Wagers AJ, Larsen PR, Simonides WS, Zavacki AM.

Endocrinology. 2019 May 1;160(5):1205-1222. doi: 10.1210/en.2019-00088.


Local hyperthyroidism promotes pancreatic acinar cell proliferation during acute pancreatitis.

Malagola E, Chen R, Bombardo M, Saponara E, Dentice M, Salvatore D, Reding T, Myers S, Hills AP, Graf R, Sonda S.

J Pathol. 2019 Jun;248(2):217-229. doi: 10.1002/path.5247. Epub 2019 Apr 4.


A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells.

Sommella E, Badolati N, Riccio G, Salviati E, Bottone S, Dentice M, Campiglia P, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2019 Jan 14;11(1). pii: E163. doi: 10.3390/nu11010163.


Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation.

Riccio G, Sommella E, Badolati N, Salviati E, Bottone S, Campiglia P, Dentice M, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2018 Nov 20;10(11). pii: E1808. doi: 10.3390/nu10111808.


Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation.

Badolati N, Sommella E, Riccio G, Salviati E, Heintz D, Bottone S, Di Cicco E, Dentice M, Tenore G, Campiglia P, Stornaiuolo M, Novellino E.

Nutrients. 2018 Oct 2;10(10). pii: E1406. doi: 10.3390/nu10101406.


Metabolic Effects of the Intracellular Regulation of Thyroid Hormone: Old Players, New Concepts.

Cicatiello AG, Di Girolamo D, Dentice M.

Front Endocrinol (Lausanne). 2018 Sep 11;9:474. doi: 10.3389/fendo.2018.00474. eCollection 2018. Review.


A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist.

Riccio G, Bottone S, La Regina G, Badolati N, Passacantilli S, Rossi GB, Accardo A, Dentice M, Silvestri R, Novellino E, Stornaiuolo M.

Biochemistry. 2018 Feb 6;57(5):839-851. doi: 10.1021/acs.biochem.7b01087. Epub 2018 Jan 19.


Thyroid hormone promotes differentiation of colon cancer stem cells.

Cicatiello AG, Ambrosio R, Dentice M.

Mol Cell Endocrinol. 2017 Dec 25;459:84-89. doi: 10.1016/j.mce.2017.03.017. Epub 2017 Mar 22. Review.


DIO2 Thr92Ala Reduces Deiodinase-2 Activity and Serum-T3 Levels in Thyroid-Deficient Patients.

Castagna MG, Dentice M, Cantara S, Ambrosio R, Maino F, Porcelli T, Marzocchi C, Garbi C, Pacini F, Salvatore D.

J Clin Endocrinol Metab. 2017 May 1;102(5):1623-1630. doi: 10.1210/jc.2016-2587.


The Concerted Action of Type 2 and Type 3 Deiodinases Regulates the Cell Cycle and Survival of Basal Cell Carcinoma Cells.

Miro C, Ambrosio R, De Stefano MA, Di Girolamo D, Di Cicco E, Cicatiello AG, Mancino G, Porcelli T, Raia M, Del Vecchio L, Salvatore D, Dentice M.

Thyroid. 2017 Apr;27(4):567-576. doi: 10.1089/thy.2016.0532. Epub 2017 Feb 22.


The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils.

van der Spek AH, Bloise FF, Tigchelaar W, Dentice M, Salvatore D, van der Wel NN, Fliers E, Boelen A.

Endocrinology. 2016 Aug;157(8):3293-305. doi: 10.1210/en.2016-1103. Epub 2016 Jun 29.


Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.

Di Girolamo D, Ambrosio R, De Stefano MA, Mancino G, Porcelli T, Luongo C, Di Cicco E, Scalia G, Vecchio LD, Colao A, Dlugosz AA, Missero C, Salvatore D, Dentice M.

J Clin Invest. 2016 Jun 1;126(6):2308-20. doi: 10.1172/JCI84465. Epub 2016 May 9.


Activated Thyroid Hormone Promotes Differentiation and Chemotherapeutic Sensitization of Colorectal Cancer Stem Cells by Regulating Wnt and BMP4 Signaling.

Catalano V, Dentice M, Ambrosio R, Luongo C, Carollo R, Benfante A, Todaro M, Stassi G, Salvatore D.

Cancer Res. 2016 Mar 1;76(5):1237-44. doi: 10.1158/0008-5472.CAN-15-1542. Epub 2015 Dec 16.


Pharmacological folding chaperones act as allosteric ligands of Frizzled4.

Generoso SF, Giustiniano M, La Regina G, Bottone S, Passacantilli S, Di Maro S, Cassese H, Bruno A, Mallardo M, Dentice M, Silvestri R, Marinelli L, Sarnataro D, Bonatti S, Novellino E, Stornaiuolo M.

Nat Chem Biol. 2015 Apr;11(4):280-6. doi: 10.1038/nchembio.1770. Epub 2015 Mar 9.


Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.

Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D.

Cell Metab. 2014 Dec 2;20(6):1038-48. doi: 10.1016/j.cmet.2014.10.009. Epub 2014 Nov 13.


The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.

Luongo C, Martin C, Vella K, Marsili A, Ambrosio R, Dentice M, Harney JW, Salvatore D, Zavacki AM, Larsen PR.

Endocrinology. 2015 Feb;156(2):745-54. doi: 10.1210/en.2014-1698. Epub 2014 Dec 2.


Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.

Castroneves LA, Jugo RH, Maynard MA, Lee JS, Wassner AJ, Dorfman D, Bronson RT, Ukomadu C, Agoston AT, Ding L, Luongo C, Guo C, Song H, Demchev V, Lee NY, Feldman HA, Vella KR, Peake RW, Hartigan C, Kellogg MD, Desai A, Salvatore D, Dentice M, Huang SA.

Endocrinology. 2014 Oct;155(10):4061-8. doi: 10.1210/en.2013-2028. Epub 2014 Jul 8.

Supplemental Content

Loading ...
Support Center