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Items: 12


SMAD4-independent activation of TGF-β signaling by MUC1 in a human pancreatic cancer cell line.

Grover P, Nath S, Nye MD, Zhou R, Ahmad M, Mukherjee P.

Oncotarget. 2018 Jan 5;9(6):6897-6910. doi: 10.18632/oncotarget.23966. eCollection 2018 Jan 23.


Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort.

Nye MD, King KE, Darrah TH, Maguire R, Jima DD, Huang Z, Mendez MA, Fry RC, Jirtle RL, Murphy SK, Hoyo C.

Environ Epigenet. 2016;2(1). pii: dvv009. doi: 10.1093/eep/dvv009. Epub 2016 Feb 15.


Geographic clustering of elevated blood heavy metal levels in pregnant women.

King KE, Darrah TH, Money E, Meentemeyer R, Maguire RL, Nye MD, Michener L, Murtha AP, Jirtle R, Murphy SK, Mendez MA, Robarge W, Vengosh A, Hoyo C.

BMC Public Health. 2015 Oct 9;15:1035. doi: 10.1186/s12889-015-2379-9.


Maternal cadmium, iron and zinc levels, DNA methylation and birth weight.

Vidal AC, Semenova V, Darrah T, Vengosh A, Huang Z, King K, Nye MD, Fry R, Skaar D, Maguire R, Murtha A, Schildkraut J, Murphy S, Hoyo C.

BMC Pharmacol Toxicol. 2015 Jul 15;16:20. doi: 10.1186/s40360-015-0020-2.


In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST.

Nye MD, Hoyo C, Murphy SK.

Toxicol In Vitro. 2015 Apr;29(3):544-50. doi: 10.1016/j.tiv.2015.01.002. Epub 2015 Jan 14.


Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury.

Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC.

Genes (Basel). 2014 Jun 11;5(2):477-96. doi: 10.3390/genes5020477.


The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner.

Nye MD, Almada LL, Fernandez-Barrena MG, Marks DL, Elsawa SF, Vrabel A, Tolosa EJ, Ellenrieder V, Fernandez-Zapico ME.

J Biol Chem. 2014 May 30;289(22):15495-506. doi: 10.1074/jbc.M113.545194. Epub 2014 Apr 16.


Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer.

Nye MD, Hoyo C, Huang Z, Vidal AC, Wang F, Overcash F, Smith JS, Vasquez B, Hernandez B, Swai B, Oneko O, Mlay P, Obure J, Gammon MD, Bartlett JA, Murphy SK.

PLoS One. 2013;8(2):e56325. doi: 10.1371/journal.pone.0056325. Epub 2013 Feb 13.


Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation.

Feng Q, Kalari K, Fridley BL, Jenkins G, Ji Y, Abo R, Hebbring S, Zhang J, Nye MD, Leeder JS, Weinshilboum RM.

Mol Genet Metab. 2011 Feb;102(2):126-33. doi: 10.1016/j.ymgme.2010.10.010. Epub 2010 Oct 21.


Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.

Huntoon CJ, Nye MD, Geng L, Peterson KL, Flatten KS, Haluska P, Kaufmann SH, Karnitz LM.

Cancer Res. 2010 Nov 1;70(21):8642-50. doi: 10.1158/0008-5472.CAN-10-1345. Epub 2010 Sep 14.


Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation.

Singh G, Singh SK, König A, Reutlinger K, Nye MD, Adhikary T, Eilers M, Gress TM, Fernandez-Zapico ME, Ellenrieder V.

J Biol Chem. 2010 Aug 27;285(35):27241-50. doi: 10.1074/jbc.M110.100438. Epub 2010 Jun 1.

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