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Items: 1 to 20 of 63

1.

Differential contributions of pre- and post- EMT tumor cells in breast cancer metastasis.

Lourenco AR, Ban Y, Crowley MJ, Lee SB, Ramchandani D, Du W, Elemento O, George JT, Jolly MK, Levine H, Sheng J, Wong STC, Altorki NK, Gao D.

Cancer Res. 2019 Nov 8. pii: canres.1427.2019. doi: 10.1158/0008-5472.CAN-19-1427. [Epub ahead of print]

PMID:
31704888
2.

Pericytes enable effective angiogenesis in the presence of proinflammatory signals.

Kang TY, Bocci F, Jolly MK, Levine H, Onuchic JN, Levchenko A.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23551-23561. doi: 10.1073/pnas.1913373116. Epub 2019 Nov 4.

PMID:
31685607
3.

Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial-mesenchymal plasticity and tumor metastasis.

Nihan Kilinc A, Sugiyama N, Reddy Kalathur RK, Antoniadis H, Birogul H, Ishay-Ronen D, George JT, Levine H, Kumar Jolly M, Christofori G.

Oncogene. 2019 Oct 30. doi: 10.1038/s41388-019-1081-2. [Epub ahead of print]

PMID:
31666683
4.

A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer.

Thangavel H, Angelis C, Vasaikar S, Bhat R, Jolly MK, Nagi C, Creighton CJ, Chen F, Dobrolecki LE, George JT, Kumar T, Abdulkareem NM, Mao S, Nardone A, Rimawi M, Osborne CK, Lewis MT, Levine H, Zhang B, Schiff R, Giuliano M, Trivedi MV.

J Clin Med. 2019 Oct 24;8(11). pii: E1772. doi: 10.3390/jcm8111772.

5.

Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS.

Kalvala A, Wallet P, Yang L, Wang C, Li H, Nam A, Nathan A, Mambetsariev I, Poroyko V, Gao H, Chu P, Sattler M, Bild A, Manuel ER, Lee PP, Jolly MK, Kulkarni P, Salgia R.

J Clin Med. 2019 Oct 18;8(10). pii: E1726. doi: 10.3390/jcm8101726.

6.

Computational Modeling of Collective Cell Migration: Mechanical and Biochemical Aspects.

Yang Y, Jolly MK, Levine H.

Adv Exp Med Biol. 2019;1146:1-11. doi: 10.1007/978-3-030-17593-1_1. Review.

PMID:
31612450
7.

Cancer Stem Cells and Epithelial-to-Mesenchymal Transition in Cancer Metastasis.

Celià-Terrassa T, Jolly MK.

Cold Spring Harb Perspect Med. 2019 Sep 30. pii: a036905. doi: 10.1101/cshperspect.a036905. [Epub ahead of print]

PMID:
31570380
8.

Dynamics of Phenotypic Heterogeneity Associated with EMT and Stemness during Cancer Progression

Jolly MK, Celià-Terrassa T.

J Clin Med. 2019 Sep 25;8(10). pii: E1542. doi: 10.3390/jcm8101542. Review.

9.

A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types.

Bocci F, Kumar Jolly M, Onuchic JN.

Cancer Res. 2019 Nov 1;79(21):5527-5535. doi: 10.1158/0008-5472.CAN-19-1726. Epub 2019 Sep 3.

PMID:
31481500
10.

Deciphering Hydrodynamic and Drug-Resistant Behaviors of Metastatic EMT Breast Cancer Cells Moving in a Constricted Microcapillary.

Nath B, Bidkar AP, Kumar V, Dalal A, Jolly MK, Ghosh SS, Biswas G.

J Clin Med. 2019 Aug 9;8(8). pii: E1194. doi: 10.3390/jcm8081194.

11.

Phenotypic heterogeneity in circulating tumor cells and its prognostic value in metastasis and overall survival.

Saxena K, Subbalakshmi AR, Jolly MK.

EBioMedicine. 2019 Aug;46:4-5. doi: 10.1016/j.ebiom.2019.07.074. Epub 2019 Aug 6. No abstract available.

12.

Acute vs. Chronic vs. Cyclic Hypoxia: Their Differential Dynamics, Molecular Mechanisms, and Effects on Tumor Progression.

Saxena K, Jolly MK.

Biomolecules. 2019 Aug 3;9(8). pii: E339. doi: 10.3390/biom9080339. Review.

13.

A possible role for epigenetic feedback regulation in the dynamics of the epithelial-mesenchymal transition (EMT).

Jia W, Deshmukh A, Mani SA, Jolly MK, Levine H.

Phys Biol. 2019 Sep 6;16(6):066004. doi: 10.1088/1478-3975/ab34df.

PMID:
31342918
14.

NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype.

Bocci F, Tripathi SC, Vilchez Mercedes SA, George JT, Casabar JP, Wong PK, Hanash SM, Levine H, Onuchic JN, Jolly MK.

Integr Biol (Camb). 2019 Jun 1;11(6):251-263. doi: 10.1093/intbio/zyz021.

15.

Small Cell Lung Cancer Therapeutic Responses Through Fractal Measurements: From Radiology to Mitochondrial Biology.

Mambetsariev I, Mirzapoiazova T, Lennon F, Jolly MK, Li H, Nasser MW, Vora L, Kulkarni P, Batra SK, Salgia R.

J Clin Med. 2019 Jul 16;8(7). pii: E1038. doi: 10.3390/jcm8071038.

16.

Functional balance between Tcf21-Slug defines cellular plasticity and migratory modalities in high grade serous ovarian cancer cell lines.

Varankar SS, More M, Abraham A, Pansare K, Kumar B, Narayanan NJ, Jolly MK, Mali AM, Bapat SA.

Carcinogenesis. 2019 Jun 25. pii: bgz119. doi: 10.1093/carcin/bgz119. [Epub ahead of print]

PMID:
31241128
17.

Quantifying Cancer Epithelial-Mesenchymal Plasticity and its Association with Stemness and Immune Response.

Jia D, Li X, Bocci F, Tripathi S, Deng Y, Jolly MK, Onuchic JN, Levine H.

J Clin Med. 2019 May 22;8(5). pii: E725. doi: 10.3390/jcm8050725. Review.

18.

Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer.

Jolly MK, Preca BT, Tripathi SC, Jia D, George JT, Hanash SM, Brabletz T, Stemmler MP, Maurer J, Levine H.

APL Bioeng. 2018 Aug 22;2(3):031908. doi: 10.1063/1.5024874. eCollection 2018 Sep.

19.

E-Cadherin Represses Anchorage-Independent Growth in Sarcomas through Both Signaling and Mechanical Mechanisms.

Jolly MK, Ware KE, Xu S, Gilja S, Shetler S, Yang Y, Wang X, Austin RG, Runyambo D, Hish AJ, Bartholf DeWitt S, George JT, Kreulen RT, Boss MK, Lazarides AL, Kerr DL, Gerber DG, Sivaraj D, Armstrong AJ, Dewhirst MW, Eward WC, Levine H, Somarelli JA.

Mol Cancer Res. 2019 Jun;17(6):1391-1402. doi: 10.1158/1541-7786.MCR-18-0763. Epub 2019 Mar 12.

20.

Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level.

Lin X, Kulkarni P, Bocci F, Schafer NP, Roy S, Tsai MY, He Y, Chen Y, Rajagopalan K, Mooney SM, Zeng Y, Weninger K, Grishaev A, Onuchic JN, Levine H, Wolynes PG, Salgia R, Rangarajan G, Uversky V, Orban J, Jolly MK.

Biomolecules. 2019 Feb 22;9(2). pii: E77. doi: 10.3390/biom9020077.

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