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Items: 1 to 20 of 36


Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy.

Gupta P, Mohammad T, Khan P, Alajmi MF, Hussain A, Rehman MT, Hassan MI.

Biomed Pharmacother. 2019 Jul 25;118:109245. doi: 10.1016/j.biopha.2019.109245. [Epub ahead of print]


Phytochemical analysis and anti-diabetic, anti-inflammatory and antioxidant activities of Loranthus acaciae Zucc. Grown in Saudi Arabia.

Noman OM, Mothana RA, Al-Rehaily AJ, Al Qahtani AS, Nasr FA, Khaled JM, Alajmi MF, Al-Said MS.

Saudi Pharm J. 2019 Jul;27(5):724-730. doi: 10.1016/j.jsps.2019.04.008. Epub 2019 Apr 20.


Alpinia zerumbet (Pers.): Food and Medicinal Plant with Potential In Vitro and In Vivo Anti-Cancer Activities.

Zahra MH, Salem TAR, El-Aarag B, Yosri N, El-Ghlban S, Zaki K, Marei AH, Abd El-Wahed A, Saeed A, Khatib A, AlAjmi MF, Shathili AM, Xiao J, Khalifa SAM, El-Seedi HR.

Molecules. 2019 Jul 8;24(13). pii: E2495. doi: 10.3390/molecules24132495.


Insight of the Interaction between 2,4-thiazolidinedione and Human Serum Albumin: A Spectroscopic, Thermodynamic and Molecular Docking Study.

Rahman S, Rehman MT, Rabbani G, Khan P, AlAjmi MF, Hassan MI, Muteeb G, Kim J.

Int J Mol Sci. 2019 Jun 3;20(11). pii: E2727. doi: 10.3390/ijms20112727.


Effects of Pro1266Leu mutation on structure and function of glycoprotein Ib binding domain of von Willebrand factor.

Naqvi AAT, Alajmi MF, Rehman T, Hussain A, Hassan I.

J Cell Biochem. 2019 May 28. doi: 10.1002/jcb.29052. [Epub ahead of print]


Effect of cetyltrimethylammonium bromide (CTAB) on the conformation of a hen egg white lysozyme: A spectroscopic and molecular docking study.

Khan JM, Malik A, Ahmed A, Rehman MT, AlAjmi MF, Khan RH, Fatima S, Alamery SF, Abdullah EM.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Aug 5;219:313-318. doi: 10.1016/j.saa.2019.04.062. Epub 2019 Apr 24.


Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach.

Amir M, Kumar V, Mohammad T, Dohare R, Rehman MT, Alajmi MF, Hussain A, Ahmad F, Hassan MI.

Biosci Rep. 2019 May 15;39(5). pii: BSR20190312. doi: 10.1042/BSR20190312. Print 2019 May 31.


Hesperidin-CAMKIV interaction and its impact on cell proliferation and apoptosis in the human hepatic carcinoma and neuroblastoma cells.

Naz H, Tarique M, Ahamad S, Alajmi MF, Hussain A, Rehman MT, Luqman S, Hassan MI.

J Cell Biochem. 2019 Sep;120(9):15119-15130. doi: 10.1002/jcb.28774. Epub 2019 Apr 25.


Impact of Gln94Glu mutation on the structure and function of protection of telomere 1, a cause of cutaneous familial melanoma.

Amir M, Ahmad S, Ahamad S, Kumar V, Mohammad T, Dohare R, Alajmi MF, Rehman T, Hussain A, Islam A, Ahmad F, Hassan MI.

J Biomol Struct Dyn. 2019 Apr 23:1-11. doi: 10.1080/07391102.2019.1610500. [Epub ahead of print]


Investigating architecture and structure-function relationships in cold shock DNA-binding domain family using structural genomics-based approach.

Amir M, Kumar V, Dohare R, Rehman MT, Hussain A, Alajmi MF, El-Seedi HR, Hassan HMA, Islam A, Ahmad F, Hassan MI.

Int J Biol Macromol. 2019 Jul 15;133:484-494. doi: 10.1016/j.ijbiomac.2019.04.135. Epub 2019 Apr 18.


Novel C-2 Symmetric Molecules as α-Glucosidase and α-Amylase Inhibitors: Design, Synthesis, Kinetic Evaluation, Molecular Docking and Pharmacokinetics.

Shahzad D, Saeed A, Larik FA, Channar PA, Abbas Q, Alajmi MF, Arshad MI, Erben MF, Hassan M, Raza H, Seo SY, El-Seedi HR.

Molecules. 2019 Apr 17;24(8). pii: E1511. doi: 10.3390/molecules24081511.


Optimization of Hyperglycemic Induction in Zebrafish and Evaluation of Its Blood Glucose Level and Metabolite Fingerprint Treated with Psychotria malayana Jack Leaf Extract.

Benchoula K, Khatib A, Quzwain FMC, Che Mohamad CA, Wan Sulaiman WMA, Abdul Wahab R, Ahmed QU, Abdul Ghaffar M, Saiman MZ, Alajmi MF, El-Seedi H.

Molecules. 2019 Apr 17;24(8). pii: E1506. doi: 10.3390/molecules24081506.


Melittin Exerts Beneficial Effects on Paraquat-Induced Lung Injuries In Mice by Modifying Oxidative Stress and Apoptosis.

El-Aarag B, Magdy M, AlAjmi MF, Khalifa SAM, El-Seedi HR.

Molecules. 2019 Apr 16;24(8). pii: E1498. doi: 10.3390/molecules24081498.


Investigating the structural features of chromodomain proteins in the human genome and predictive impacts of their mutations in cancers.

Dahiya R, Naqvi AAT, Mohammad T, Alajmi MF, Rehman MT, Hussain A, Hassan MI.

Int J Biol Macromol. 2019 Jun 15;131:1101-1116. doi: 10.1016/j.ijbiomac.2019.03.162. Epub 2019 Mar 24.


Biosynthesized Silver Nanoparticle (AgNP) From Pandanus odorifer Leaf Extract Exhibits Anti-metastasis and Anti-biofilm Potentials.

Hussain A, Alajmi MF, Khan MA, Pervez SA, Ahmed F, Amir S, Husain FM, Khan MS, Shaik GM, Hassan I, Khan RA, Rehman MT.

Front Microbiol. 2019 Feb 12;10:8. doi: 10.3389/fmicb.2019.00008. eCollection 2019.


Drug-1,3,4-Thiadiazole Conjugates as Novel Mixed-Type Inhibitors of Acetylcholinesterase: Synthesis, Molecular Docking, Pharmacokinetics, and ADMET Evaluation.

Ujan R, Saeed A, Channar PA, Larik FA, Abbas Q, Alajmi MF, El-Seedi HR, Rind MA, Hassan M, Raza H, Seo SY.

Molecules. 2019 Feb 28;24(5). pii: E860. doi: 10.3390/molecules24050860.


Food additive dye (quinoline yellow) promotes unfolding and aggregation of myoglobin: A spectroscopic and molecular docking analysis.

Khan MS, Rehman MT, Bhat SA, Tabrez S, Hussain A, Husain FM, AlAjmi MF, Alamery SF, Sumbul S.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 May 5;214:216-226. doi: 10.1016/j.saa.2019.01.090. Epub 2019 Feb 13.


High-Throughput Virtual Screening, Molecular Dynamics Simulation, and Enzyme Kinetics Identified ZINC84525623 as a Potential Inhibitor of NDM-1.

Rehman MT, AlAjmi MF, Hussain A, Rather GM, Khan MA.

Int J Mol Sci. 2019 Feb 14;20(4). pii: E819. doi: 10.3390/ijms20040819.


Comparative evaluation of cytotoxic, antimicrobial and antioxidant activities of the crude extracts of three Plectranthus species grown in Saudi Arabia.

Mothana RA, Khaled JM, El-Gamal AA, Noman OM, Kumar A, Alajmi MF, Al-Rehaily AJ, Al-Said MS.

Saudi Pharm J. 2019 Feb;27(2):162-170. doi: 10.1016/j.jsps.2018.09.010. Epub 2018 Sep 25.


Future of Ionic Liquids for Chiral Separations in High-Performance Liquid Chromatography and Capillary Electrophoresis.

Hussain A, AlAjmi MF, Hussain I, Ali I.

Crit Rev Anal Chem. 2019;49(4):289-305. doi: 10.1080/10408347.2018.1523706. Epub 2018 Dec 24. Review.


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