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Items: 1 to 20 of 82

1.

Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations.

Vazquez JH, Clemens MM, Allard FD, Yee EU, Kennon-McGill S, Mackintosh SG, Jaeschke H, Hambuchen MD, McGill MR.

Toxicol Sci. 2020 Feb 1;173(2):244-254. doi: 10.1093/toxsci/kfz222.

PMID:
31651977
2.

What's Causing This Dark Brown Plasma?

Tesfazghi MT, McGill MR, Yarbrough ML.

J Appl Lab Med. 2019 Jul;4(1):125-129. doi: 10.1373/jalm.2018.026633. Epub 2018 Nov 30. No abstract available.

PMID:
31639715
3.

Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children.

McCullough S, Dweep H, McGill MR, Bhattacharyya S, James L, Frankowski S, Woodall A, Kearns G, Gill P.

Microrna. 2019 Aug 8. doi: 10.2174/2211536608666190808144456. [Epub ahead of print]

PMID:
31393259
4.

Effect of Bile Duct Ligation-induced Liver Dysfunction on Methamphetamine Pharmacokinetics and Locomotor Activity in Rats.

Hambuchen MD, Berquist MD, Simecka CM, McGill MR, Gunnell MG, Hendrickson HP, Owens SM.

J Pharm Pharm Sci. 2019;22(1):301-312. doi: 10.18433/jpps30471.

5.

Mechanisms and biomarkers of liver regeneration after drug-induced liver injury.

Clemens MM, McGill MR, Apte U.

Adv Pharmacol. 2019;85:241-262. doi: 10.1016/bs.apha.2019.03.001. Epub 2019 Mar 21. Review.

PMID:
31307589
6.

Biomarkers of drug-induced liver injury.

McGill MR, Jaeschke H.

Adv Pharmacol. 2019;85:221-239. doi: 10.1016/bs.apha.2019.02.001. Epub 2019 Mar 6. Review.

PMID:
31307588
7.

Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration.

Ewing LE, McGill MR, Yee EU, Quick CM, Skinner CM, Kennon-McGill S, Clemens M, Vazquez JH, McCullough SS, Williams DK, Kutanzi KR, Walker LA, ElSohly MA, James LP, Gurley BJ, Koturbash I.

Molecules. 2019 Jun 17;24(12). pii: E2256. doi: 10.3390/molecules24122256.

8.

Expression of drug metabolizing enzymes and transporters in the cochlea: Implications for drug delivery and ototoxicity.

Kennon-McGill S, Clemens MM, McGill MR.

Hear Res. 2019 Aug;379:98-102. doi: 10.1016/j.heares.2019.05.002. Epub 2019 May 15.

PMID:
31121337
9.

Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model.

Ewing LE, Skinner CM, Quick CM, Kennon-McGill S, McGill MR, Walker LA, ElSohly MA, Gurley BJ, Koturbash I.

Molecules. 2019 Apr 30;24(9). pii: E1694. doi: 10.3390/molecules24091694.

10.

Animal models of drug-induced liver injury.

McGill MR, Jaeschke H.

Biochim Biophys Acta Mol Basis Dis. 2019 May 1;1865(5):1031-1039. doi: 10.1016/j.bbadis.2018.08.037. Epub 2018 Sep 3. Review.

PMID:
31007174
11.

Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F₁ Mice.

Gurley BJ, Miousse IR, Nookaew I, Ewing LE, Skinner CM, Jenjaroenpun P, Wongsurawat T, Kennon-McGill S, Avula B, Bae JY, McGill MR, Ussery D, Khan IA, Koturbash I.

Nutrients. 2019 Apr 3;11(4). pii: E776. doi: 10.3390/nu11040776.

12.

Propagation of Pericentral Necrosis During Acetaminophen-Induced Liver Injury: Evidence for Early Interhepatocyte Communication and Information Exchange.

Kennedy RC, Smith AK, Ropella GEP, McGill MR, Jaeschke H, Hunt CA.

Toxicol Sci. 2019 May 1;169(1):151-166. doi: 10.1093/toxsci/kfz029.

13.

The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.

Clemens MM, Kennon-McGill S, Apte U, James LP, Finck BN, McGill MR.

Food Chem Toxicol. 2019 Mar;125:279-288. doi: 10.1016/j.fct.2019.01.014. Epub 2019 Jan 14.

PMID:
30654094
14.

Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways.

Kennedy JL, Kurten RC, McCullough S, Panettieri RA, Koziol-White C, Jones SM, Caid K, Gill PS, Roberts D, Jaeschke H, McGill MR, James L.

Xenobiotica. 2019 Sep;49(9):1106-1115. doi: 10.1080/00498254.2018.1536814. Epub 2019 Jan 30.

PMID:
30328361
15.

The Problem With Predictive Values: Are We Using the Right Metrics for Preclinical Prediction of Drug Hepatotoxicity?

McGill MR.

Toxicol Sci. 2018 Sep 1;165(1):3-4. doi: 10.1093/toxsci/kfy157. No abstract available.

PMID:
30165627
16.

Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation.

McGill MR, Jaeschke H.

Expert Rev Mol Diagn. 2018 Sep;18(9):797-807. doi: 10.1080/14737159.2018.1508998. Epub 2018 Aug 13. Review.

17.

Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.

Lutkewitte AJ, Schweitzer GG, Kennon-McGill S, Clemens MM, James LP, Jaeschke H, Finck BN, McGill MR.

Food Chem Toxicol. 2018 May;115:273-283. doi: 10.1016/j.fct.2018.03.014. Epub 2018 Mar 11. No abstract available.

18.

Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis.

McGreal SR, Bhushan B, Walesky C, McGill MR, Lebofsky M, Kandel SE, Winefield RD, Jaeschke H, Zachara NE, Zhang Z, Tan EP, Slawson C, Apte U.

Toxicol Sci. 2018 Apr 1;162(2):599-610. doi: 10.1093/toxsci/kfy002.

19.

Increased C-Reactive Protein in Healthy Controls.

McGill MR, Gronowski AM.

Clin Chem. 2018 Jan;64(1):242-243. doi: 10.1373/clinchem.2017.274746. No abstract available.

PMID:
29295839
20.

Extrahepatic toxicity of acetaminophen: critical evaluation of the evidence and proposed mechanisms.

Kennon-McGill S, McGill MR.

J Clin Transl Res. 2017 Nov 18;3(3):297-310. eCollection 2018 Jan 15. Review.

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