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Items: 1 to 20 of 74

1.

LRRK2 in Parkinson disease: challenges of clinical trials.

Tolosa E, Vila M, Klein C, Rascol O.

Nat Rev Neurol. 2020 Feb;16(2):97-107. doi: 10.1038/s41582-019-0301-2. Epub 2020 Jan 24. Review.

PMID:
31980808
2.

Autophagic- and Lysosomal-Related Biomarkers for Parkinson's Disease: Lights and Shadows.

Xicoy H, Peñuelas N, Vila M, Laguna A.

Cells. 2019 Oct 25;8(11). pii: E1317. doi: 10.3390/cells8111317. Review.

3.

Intracellular crowding by age-dependent neuromelanin accumulation disrupts neuronal proteostasis and triggers Parkinson disease pathology.

Vila M, Laguna A, Carballo-Carbajal I.

Autophagy. 2019 Nov;15(11):2028-2030. doi: 10.1080/15548627.2019.1659621. Epub 2019 Sep 3.

4.

Neuromelanin, aging, and neuronal vulnerability in Parkinson's disease.

Vila M.

Mov Disord. 2019 Oct;34(10):1440-1451. doi: 10.1002/mds.27776. Epub 2019 Jun 28.

PMID:
31251435
5.

Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis.

Carballo-Carbajal I, Laguna A, Romero-Giménez J, Cuadros T, Bové J, Martinez-Vicente M, Parent A, Gonzalez-Sepulveda M, Peñuelas N, Torra A, Rodríguez-Galván B, Ballabio A, Hasegawa T, Bortolozzi A, Gelpi E, Vila M.

Nat Commun. 2019 Mar 7;10(1):973. doi: 10.1038/s41467-019-08858-y.

6.

Parkinson disease, substantia nigra vulnerability, and calbindin expression: Enlightening the darkness?

Blesa J, Vila M.

Mov Disord. 2019 Feb;34(2):161-163. doi: 10.1002/mds.27618. Epub 2019 Jan 24. No abstract available.

PMID:
30675930
7.

The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21.

Lassot I, Mora S, Lesage S, Zieba BA, Coque E, Condroyer C, Bossowski JP, Mojsa B, Marelli C, Soulet C, Tesson C, Carballo-Carbajal I, Laguna A, Mangone G, Vila M, Brice A, Desagher S.

Cell Rep. 2018 Nov 27;25(9):2484-2496.e9. doi: 10.1016/j.celrep.2018.11.002.

8.

Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease.

Franco-Iborra S, Cuadros T, Parent A, Romero-Gimenez J, Vila M, Perier C.

Cell Death Dis. 2018 Nov 7;9(11):1122. doi: 10.1038/s41419-018-1154-0.

9.

Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease.

Franco-Iborra S, Vila M, Perier C.

Front Neurosci. 2018 May 23;12:342. doi: 10.3389/fnins.2018.00342. eCollection 2018. Review.

10.

Overexpression of TFEB Drives a Pleiotropic Neurotrophic Effect and Prevents Parkinson's Disease-Related Neurodegeneration.

Torra A, Parent A, Cuadros T, Rodríguez-Galván B, Ruiz-Bronchal E, Ballabio A, Bortolozzi A, Vila M, Bové J.

Mol Ther. 2018 Jun 6;26(6):1552-1567. doi: 10.1016/j.ymthe.2018.02.022. Epub 2018 Feb 27.

11.

Correction to: The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.

Kim H, Calatayud C, Guha S, Fernández-Carasa I, Berkowitz L, Carballo-Carbajal I, Ezquerra M, Fernández-Santiago R, Kapahi P, Raya Á, Miranda-Vizuete A, Lizcano JM, Vila M, Caldwell KA, Caldwell GA, Consiglio A, Dalfo E.

Mol Neurobiol. 2018 Sep;55(9):7553-7554. doi: 10.1007/s12035-018-1010-3.

12.

The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.

Kim H, Calatayud C, Guha S, Fernández-Carasa I, Berkowitz L, Carballo-Carbajal I, Ezquerra M, Fernández-Santiago R, Kapahi P, Raya Á, Miranda-Vizuete A, Lizcano JM, Vila M, Caldwell KA, Caldwell GA, Consiglio A, Dalfo E.

Mol Neurobiol. 2018 Sep;55(9):7533-7552. doi: 10.1007/s12035-018-0881-7. Epub 2018 Feb 10. Erratum in: Mol Neurobiol. 2018 Apr 2;:.

13.

Lack of pathogenic potential of peripheral α-synuclein aggregates from Parkinson's disease patients.

Recasens A, Carballo-Carbajal I, Parent A, Bové J, Gelpi E, Tolosa E, Vila M.

Acta Neuropathol Commun. 2018 Feb 8;6(1):8. doi: 10.1186/s40478-018-0509-1.

14.

Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease.

Alarcón-Arís D, Recasens A, Galofré M, Carballo-Carbajal I, Zacchi N, Ruiz-Bronchal E, Pavia-Collado R, Chica R, Ferrés-Coy A, Santos M, Revilla R, Montefeltro A, Fariñas I, Artigas F, Vila M, Bortolozzi A.

Mol Ther. 2018 Feb 7;26(2):550-567. doi: 10.1016/j.ymthe.2017.11.015. Epub 2017 Nov 29.

15.

Synaptic Regulator α-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells.

Perez-Villalba A, Sirerol-Piquer MS, Belenguer G, Soriano-Cantón R, Muñoz-Manchado AB, Villadiego J, Alarcón-Arís D, Soria FN, Dehay B, Bezard E, Vila M, Bortolozzi A, Toledo-Aral JJ, Pérez-Sánchez F, Fariñas I.

J Neurosci. 2018 Jan 24;38(4):814-825. doi: 10.1523/JNEUROSCI.2276-17.2017. Epub 2017 Dec 7.

16.

Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.

Soria FN, Engeln M, Martinez-Vicente M, Glangetas C, López-González MJ, Dovero S, Dehay B, Normand E, Vila M, Favereaux A, Georges F, Lo Bianco C, Bezard E, Fernagut PO.

Hum Mol Genet. 2017 Jul 15;26(14):2603-2615. doi: 10.1093/hmg/ddx120.

PMID:
28520872
17.

Erratum to: Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons.

Urrea L, Segura-Feliu M, Masuda-Suzukake M, Hervera A, Pedraz L, García-Aznar JM, Vila M, Samitier J, Torrents E, Ferrer I, Gavín R, Hagesawa M, Del Río JA.

Mol Neurobiol. 2018 Mar;55(3):1861. doi: 10.1007/s12035-017-0553-z. No abstract available.

18.

Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons.

Urrea L, Segura-Feliu M, Masuda-Suzukake M, Hervera A, Pedraz L, García-Aznar JM, Vila M, Samitier J, Torrents E, Ferrer I, Gavín R, Hagesawa M, Del Río JA.

Mol Neurobiol. 2018 Mar;55(3):1847-1860. doi: 10.1007/s12035-017-0451-4. Epub 2017 Feb 22. Erratum in: Mol Neurobiol. 2017 May 5;:.

19.

Functional Rescue of Dopaminergic Neuron Loss in Parkinson's Disease Mice After Transplantation of Hematopoietic Stem and Progenitor Cells.

Altarche-Xifro W, di Vicino U, Muñoz-Martin MI, Bortolozzi A, Bové J, Vila M, Cosma MP.

EBioMedicine. 2016 Jun;8:83-95. doi: 10.1016/j.ebiom.2016.04.016. Epub 2016 Apr 19.

20.

Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy.

García-Lezana T, Oria M, Romero-Giménez J, Bové J, Vila M, Genescà J, Chavarria L, Cordoba J.

J Cereb Blood Flow Metab. 2017 Mar;37(3):927-937. doi: 10.1177/0271678X16649196. Epub 2016 Jul 20.

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