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Items: 1 to 20 of 29


Characterization of Soybean Germinated Embryo Extract as an Estrogen Receptor Subtype-Selective and Tissue-Specific Modulator.

Jeong H, Lee J, Kim S, Park S, Yang H, Ahn BH, Jang CY, Jeong HC, Lee SJ, Kim SL, Seo WD, Sohn J, Chang M.

J Med Food. 2019 Feb;22(2):186-195. doi: 10.1089/jmf.2018.4250. Epub 2018 Dec 26.


Inhibitory and Inductive Effects of Opuntia ficus indica Extract and Its Flavonoid Constituents on Cytochrome P450s and UDP-Glucuronosyltransferases.

Jeong H, Kim S, Kim MY, Lee J, An BH, Kim HD, Jeong H, Song YS, Chang M.

Int J Mol Sci. 2018 Oct 30;19(11). pii: E3400. doi: 10.3390/ijms19113400.


Hepatic Metabolism of Sakuranetin and Its Modulating Effects on Cytochrome P450s and UDP-Glucuronosyltransferases.

Jeong H, Lee J, Kim S, Yeo YY, So H, Wu H, Song YS, Jang CY, Kim HD, Kim MJ, Chang M.

Molecules. 2018 Jun 26;23(7). pii: E1542. doi: 10.3390/molecules23071542.


Estrogenic effects of phytoestrogens derived from Flemingia strobilifera in MCF-7 cells and immature rats.

Jeong SY, Chang M, Choi SH, Oh SR, Wu HH, Zhu Y, Gao XM, Wang X, Zhang B, Lim DS, Lee JY, Kim SD, Song YS.

Arch Pharm Res. 2018 May;41(5):519-529. doi: 10.1007/s12272-018-1027-1. Epub 2018 May 24.


Spiroketones and a Biphenyl Analog from Stems and Leaves of Larrea nitida and Their Inhibitory Activity against IL-6 Production.

Ahn J, Pei Y, Chae HS, Kim SH, Kim YM, Choi YH, Lee J, Chang M, Song YS, Rodriguez R, Oh DC, Kim J, Choi S, Joo SH, Chin YW.

Molecules. 2018 Jan 31;23(2). pii: E302. doi: 10.3390/molecules23020302.


Characterization of Phase I and Phase II Hepatic Metabolism and Reactive Intermediates of Larrea nitida Cav. and Its Lignan Compounds.

Jeong H, Kim S, Lee J, Park JY, Zhou W, Liu X, Kim SD, Song YS, Jang CY, Oh SR, Choi S, Chang M.

Phytother Res. 2017 Jan;31(1):140-151. doi: 10.1002/ptr.5742. Epub 2016 Nov 7.


Evaluation of the Biological Activity of Opuntia ficus indica as a Tissue- and Estrogen Receptor Subtype-Selective Modulator.

An BH, Jeong H, Zhou W, Liu X, Kim S, Jang CY, Kim HS, Sohn J, Park HJ, Sung NH, Hong CY, Chang M.

Phytother Res. 2016 Jun;30(6):971-80. doi: 10.1002/ptr.5602. Epub 2016 Mar 14.


Metformin inhibits early stage diethylnitrosamine‑induced hepatocarcinogenesis in rats.

Jo W, Yu ES, Chang M, Park HK, Choi HJ, Ryu JE, Jang S, Lee HJ, Jang JJ, Son WC.

Mol Med Rep. 2016 Jan;13(1):146-52. doi: 10.3892/mmr.2015.4513. Epub 2015 Nov 6.


Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells.

Jang YJ, Won JH, Back MJ, Fu Z, Jang JM, Ha HC, Hong S, Chang M, Kim DK.

Biomol Ther (Seoul). 2015 Sep;23(5):407-13. doi: 10.4062/biomolther.2015.075. Epub 2015 Sep 1.


Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells.

Woo YM, Shin Y, Lee EJ, Lee S, Jeong SH, Kong HK, Park EY, Kim HK, Han J, Chang M, Park JH.

PLoS One. 2015 Jul 9;10(7):e0132285. doi: 10.1371/journal.pone.0132285. eCollection 2015.


Human glutathione S-transferase P1-1 functions as an estrogen receptor α signaling modulator.

Liu X, An BH, Kim MJ, Park JH, Kang YS, Chang M.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):840-4. doi: 10.1016/j.bbrc.2014.09.017. Epub 2014 Sep 16.


Selective Estrogen Receptor Modulation by Larrea nitida on MCF-7 Cell Proliferation and Immature Rat Uterus.

Ahn HN, Jeong SY, Bae GU, Chang M, Zhang D, Liu X, Pei Y, Chin YW, Lee J, Oh SR, Song YS.

Biomol Ther (Seoul). 2014 Jul;22(4):347-54. doi: 10.4062/biomolther.2014.050.


Carcinogenicity study of CKD-501, a novel dual peroxisome proliferator-activated receptors α and γ agonist, following oral administration to Sprague Dawley rats for 94-101 weeks.

Lee HS, Chang M, Lee JE, Kim W, Hwang IC, Kim DH, Park HK, Choi HJ, Jo W, Cha SW, Son WC.

Regul Toxicol Pharmacol. 2014 Jul;69(2):207-16. doi: 10.1016/j.yrtph.2014.04.003. Epub 2014 Apr 18.


Psoralidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia.

Liu X, Nam JW, Song YS, Viswanath AN, Pae AN, Kil YS, Kim HD, Park JH, Seo EK, Chang M.

Bioorg Med Chem Lett. 2014 Mar 1;24(5):1403-6. doi: 10.1016/j.bmcl.2014.01.029. Epub 2014 Jan 20.


Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice.

Yang J, Ahn HN, Chang M, Narasimhan P, Chan PH, Song YS.

J Neurochem. 2013 Feb;124(4):523-35. doi: 10.1111/jnc.12111. Epub 2012 Dec 28.


Tamoxifen resistance in breast cancer.

Chang M.

Biomol Ther (Seoul). 2012 May;20(3):256-67. doi: 10.4062/biomolther.2012.20.3.256. Review.


Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities.

Kim HJ, Lee SH, Koh JS, Lee SH.

Bioorg Med Chem Lett. 2012 May 1;22(9):3067-71. doi: 10.1016/j.bmcl.2012.03.070. Epub 2012 Mar 27. Erratum in: Bioorg Med Chem Lett. 2014 Apr 1;24(7):1862. Kim, Aeri [corrected to Lee, Sun Hwa].


GATA-binding protein 1 is a novel transcription regulator of peroxiredoxin 5 in human breast cancer cells.

Seo MJ, Liu X, Chang M, Park JH.

Int J Oncol. 2012 Mar;40(3):655-64. doi: 10.3892/ijo.2011.1236. Epub 2011 Oct 20.


Dual roles of estrogen metabolism in mammary carcinogenesis.

Chang M.

BMB Rep. 2011 Jul;44(7):423-34. doi: 10.5483/BMBRep.2011.44.7.423. Review.


Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation.

Peng KW, Chang M, Wang YT, Wang Z, Qin Z, Bolton JL, Thatcher GR.

Chem Res Toxicol. 2010 Aug 16;23(8):1374-83. doi: 10.1021/tx100129h.

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