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Items: 10


A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.

Romano G, Chen PL, Song P, McQuade JL, Liang RJ, Liu M, Roh W, Duose DY, Carapeto FCL, Li J, Teh JLF, Aplin AE, Chen M, Zhang J, Lazar AJ, Davies MA, Futreal PA, Amaria RN, Zhang DY, Wargo JA, Kwong LN.

Cancer Discov. 2018 May;8(5):556-567. doi: 10.1158/2159-8290.CD-17-0745. Epub 2018 Mar 1.


Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma.

Kwong LN, Zou L, Chagani S, Pedamallu CS, Liu M, Jiang S, Protopopov A, Zhang J, Getz G, Chin L.

Cell Rep. 2017 May 16;19(7):1304-1312. doi: 10.1016/j.celrep.2017.04.065.


Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis.

Xue J, Lin X, Chiu WT, Chen YH, Yu G, Liu M, Feng XH, Sawaya R, Medema RH, Hung MC, Huang S.

J Clin Invest. 2014 Feb;124(2):564-79. doi: 10.1172/JCI71104. Epub 2014 Jan 2.


PML regulates PER2 nuclear localization and circadian function.

Miki T, Xu Z, Chen-Goodspeed M, Liu M, Van Oort-Jansen A, Rea MA, Zhao Z, Lee CC, Chang KS.

EMBO J. 2012 Mar 21;31(6):1427-39. doi: 10.1038/emboj.2012.1. Epub 2012 Jan 24.


FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis.

Zhang N, Wei P, Gong A, Chiu WT, Lee HT, Colman H, Huang H, Xue J, Liu M, Wang Y, Sawaya R, Xie K, Yung WK, Medema RH, He X, Huang S.

Cancer Cell. 2011 Oct 18;20(4):427-42. doi: 10.1016/j.ccr.2011.08.016.


FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes.

Dai B, Pieper RO, Li D, Wei P, Liu M, Woo SY, Aldape KD, Sawaya R, Xie K, Huang S.

Cancer Res. 2010 Apr 1;70(7):2951-61. doi: 10.1158/0008-5472.CAN-09-3909. Epub 2010 Mar 23.


FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells.

Zhang Y, Zhang N, Dai B, Liu M, Sawaya R, Xie K, Huang S.

Cancer Res. 2008 Nov 1;68(21):8733-42. doi: 10.1158/0008-5472.CAN-08-1968.


FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells.

Liu M, Dai B, Kang SH, Ban K, Huang FJ, Lang FF, Aldape KD, Xie TX, Pelloski CE, Xie K, Sawaya R, Huang S.

Cancer Res. 2006 Apr 1;66(7):3593-602.


Activation of stat3 in human melanoma promotes brain metastasis.

Xie TX, Huang FJ, Aldape KD, Kang SH, Liu M, Gershenwald JE, Xie K, Sawaya R, Huang S.

Cancer Res. 2006 Mar 15;66(6):3188-96.


Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.

Xie TX, Wei D, Liu M, Gao AC, Ali-Osman F, Sawaya R, Huang S.

Oncogene. 2004 Apr 29;23(20):3550-60.


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