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Items: 1 to 20 of 29

1.

Auraptene Mitigates Parkinson's Disease-Like Behavior by Protecting Inhibition of Mitochondrial Respiration and Scavenging Reactive Oxygen Species.

Jang Y, Choo H, Lee MJ, Han J, Kim SJ, Ju X, Cui J, Lee YL, Ryu MJ, Oh ES, Choi SY, Chung W, Kweon GR, Heo JY.

Int J Mol Sci. 2019 Jul 11;20(14). pii: E3409. doi: 10.3390/ijms20143409.

2.

Non-cell autonomous modulation of tyrosine hydroxylase by HMGB1 released from astrocytes in an acute MPTP-induced Parkinsonian mouse model.

Kim SJ, Ryu MJ, Han J, Jang Y, Lee MJ, Ju X, Ryu I, Lee YL, Oh E, Chung W, Heo JY, Kweon GR.

Lab Invest. 2019 May 1. doi: 10.1038/s41374-019-0254-5. [Epub ahead of print]

PMID:
31043679
3.

L‑Deprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration.

Ryu I, Ryu MJ, Han J, Kim SJ, Lee MJ, Ju X, Yoo BH, Lee YL, Jang Y, Song IC, Chung W, Oh E, Heo JY, Kweon GR.

Oncol Rep. 2018 Dec;40(6):3869-3878. doi: 10.3892/or.2018.6753. Epub 2018 Oct 1.

PMID:
30272370
4.

Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition.

Huang H, Lee SH, Sousa-Lima I, Kim SS, Hwang WM, Dagon Y, Yang WM, Cho S, Kang MC, Seo JA, Shibata M, Cho H, Belew GD, Bhin J, Desai BN, Ryu MJ, Shong M, Li P, Meng H, Chung BH, Hwang D, Kim MS, Park KS, Macedo MP, White M, Jones J, Kim YB.

J Clin Invest. 2018 Dec 3;128(12):5335-5350. doi: 10.1172/JCI63562. Epub 2018 Oct 29.

5.

Activation of the HMGB1-RAGE axis upregulates TH expression in dopaminergic neurons via JNK phosphorylation.

Kim SJ, Ryu MJ, Han J, Jang Y, Kim J, Lee MJ, Ryu I, Ju X, Oh E, Chung W, Kweon GR, Heo JY.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):358-364. doi: 10.1016/j.bbrc.2017.09.017. Epub 2017 Sep 5.

PMID:
28887039
6.

Growth Differentiation Factor 15 Mediates Systemic Glucose Regulatory Action of T-Helper Type 2 Cytokines.

Lee SE, Kang SG, Choi MJ, Jung SB, Ryu MJ, Chung HK, Chang JY, Kim YK, Lee JH, Kim KS, Kim HJ, Lee HK, Yi HS, Shong M.

Diabetes. 2017 Nov;66(11):2774-2788. doi: 10.2337/db17-0333. Epub 2017 Sep 5.

7.

A High-fat Diet Induces a Loss of Midbrain Dopaminergic Neuronal Function That Underlies Motor Abnormalities.

Jang Y, Lee MJ, Han J, Kim SJ, Ryu I, Ju X, Ryu MJ, Chung W, Oh E, Kweon GR, Heo JY.

Exp Neurobiol. 2017 Apr;26(2):104-112. doi: 10.5607/en.2017.26.2.104. Epub 2017 Apr 21.

8.

ANGPTL6 expression is coupled with mitochondrial OXPHOS function to regulate adipose FGF21.

Kang SG, Yi HS, Choi MJ, Ryu MJ, Jung S, Chung HK, Chang JY, Kim YK, Lee SE, Kim HW, Choi H, Kim DS, Lee JH, Kim KS, Kim HJ, Lee CH, Oike Y, Shong M.

J Endocrinol. 2017 Apr;233(1):105-118. doi: 10.1530/JOE-16-0549. Epub 2017 Feb 9.

PMID:
28184000
9.

CR6-Interacting Factor 1 Deficiency Impairs Vascular Function by Inhibiting the Sirt1-Endothelial Nitric Oxide Synthase Pathway.

Nagar H, Jung SB, Ryu MJ, Choi SJ, Piao S, Song HJ, Kang SK, Shin N, Kim DW, Jin SA, Jeong JO, Irani K, Jeon BH, Shong M, Kweon GR, Kim CS.

Antioxid Redox Signal. 2017 Aug 1;27(4):234-249. doi: 10.1089/ars.2016.6719. Epub 2017 May 24.

PMID:
28117598
10.

Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.

Chung HK, Ryu D, Kim KS, Chang JY, Kim YK, Yi HS, Kang SG, Choi MJ, Lee SE, Jung SB, Ryu MJ, Kim SJ, Kweon GR, Kim H, Hwang JH, Lee CH, Lee SJ, Wall CE, Downes M, Evans RM, Auwerx J, Shong M.

J Cell Biol. 2017 Jan 2;216(1):149-165. doi: 10.1083/jcb.201607110. Epub 2016 Dec 16.

11.

Sevoflurane Exposure during the Critical Period Affects Synaptic Transmission and Mitochondrial Respiration but Not Long-term Behavior in Mice.

Chung W, Ryu MJ, Heo JY, Lee S, Yoon S, Park H, Park S, Kim Y, Kim YH, Yoon SH, Shin YS, Lee WH, Ju X, Kweon GR, Ko Y.

Anesthesiology. 2017 Feb;126(2):288-299. doi: 10.1097/ALN.0000000000001470.

PMID:
27922840
12.

The Roles of Adipokines, Proinflammatory Cytokines, and Adipose Tissue Macrophages in Obesity-Associated Insulin Resistance in Modest Obesity and Early Metabolic Dysfunction.

Kang YE, Kim JM, Joung KH, Lee JH, You BR, Choi MJ, Ryu MJ, Ko YB, Lee MA, Lee J, Ku BJ, Shong M, Lee KH, Kim HJ.

PLoS One. 2016 Apr 21;11(4):e0154003. doi: 10.1371/journal.pone.0154003. eCollection 2016.

13.

Metabolic characterization of imatinib-resistant BCR-ABL T315I chronic myeloid leukemia cells indicates down-regulation of glycolytic pathway and low ROS production.

Ko BW, Han J, Heo JY, Jang Y, Kim SJ, Kim J, Lee MJ, Ryu MJ, Song IC, Jo YS, Kweon GR.

Leuk Lymphoma. 2016 Sep;57(9):2180-8. doi: 10.3109/10428194.2016.1142086. Epub 2016 Feb 8.

PMID:
26854822
14.

Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation.

Jang Y, Han J, Kim SJ, Kim J, Lee MJ, Jeong S, Ryu MJ, Seo KS, Choi SY, Shong M, Lim K, Heo JY, Kweon GR.

Oncotarget. 2015 Nov 10;6(35):38127-38. doi: 10.18632/oncotarget.5511.

15.

High-capacity glycolytic and mitochondrial oxidative metabolisms mediate the growth ability of glioblastoma.

Kim J, Han J, Jang Y, Kim SJ, Lee MJ, Ryu MJ, Kweon GR, Heo JY.

Int J Oncol. 2015 Sep;47(3):1009-16. doi: 10.3892/ijo.2015.3101. Epub 2015 Jul 21.

PMID:
26202438
16.

Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure.

Kim YK, Joung KH, Ryu MJ, Kim SJ, Kim H, Chung HK, Lee MH, Lee SE, Choi MJ, Chang JY, Hong HJ, Kim KS, Lee SH, Kweon GR, Kim H, Lee CH, Kim HJ, Shong M.

Diabetologia. 2015 Apr;58(4):771-80. doi: 10.1007/s00125-015-3506-y. Epub 2015 Feb 8.

PMID:
25660120
17.

Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans.

Lee MH, Lee JU, Joung KH, Kim YK, Ryu MJ, Lee SE, Kim SJ, Chung HK, Choi MJ, Chang JY, Lee SH, Kweon GR, Kim HJ, Kim KS, Kim SM, Jo YS, Park J, Cheng SY, Shong M.

Endocrinology. 2015 Mar;156(3):1181-93. doi: 10.1210/en.2014-1670. Epub 2015 Jan 2.

18.

The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation.

Chung HK, Kim YK, Park JH, Ryu MJ, Chang JY, Hwang JH, Lee CH, Kim SH, Kim HJ, Kweon GR, Kim KS, Shong M.

Liver Int. 2015 Apr;35(4):1341-53. doi: 10.1111/liv.12741. Epub 2015 Jan 10.

PMID:
25443620
19.

NAD(P)H: quinone oxidoreductase 1 and NRH:quinone oxidoreductase 2 polymorphisms in papillary thyroid microcarcinoma: correlation with phenotype.

Lee J, Kim KS, Lee MH, Kim YS, Lee MH, Lee SE, Kim YK, Ryu MJ, Kim SJ, Choi MJ, Jo YS.

Yonsei Med J. 2013 Sep;54(5):1158-67. doi: 10.3349/ymj.2013.54.5.1158.

20.

Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice.

Ryu MJ, Kim SJ, Kim YK, Choi MJ, Tadi S, Lee MH, Lee SE, Chung HK, Jung SB, Kim HJ, Jo YS, Kim KS, Lee SH, Kim JM, Kweon GR, Park KC, Lee JU, Kong YY, Lee CH, Chung J, Shong M.

PLoS Genet. 2013;9(3):e1003356. doi: 10.1371/journal.pgen.1003356. Epub 2013 Mar 14.

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