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Items: 1 to 20 of 29

1.

Host-Targeted Therapeutics against Multidrug Resistant Intracellular Staphylococcus aureus.

Bravo-Santano N, Behrends V, Letek M.

Antibiotics (Basel). 2019 Nov 28;8(4). pii: E241. doi: 10.3390/antibiotics8040241. Review.

2.

Mycoredoxins Are Required for Redox Homeostasis and Intracellular Survival in the Actinobacterial Pathogen Rhodococcus equi.

Mourenza Á, Bravo-Santano N, Pradal I, Gil JA, Mateos LM, Letek M.

Antioxidants (Basel). 2019 Nov 15;8(11). pii: E558. doi: 10.3390/antiox8110558.

3.

Identification of novel targets for host-directed therapeutics against intracellular Staphylococcus aureus.

Bravo-Santano N, Capilla-Lasheras P, Mateos LM, Calle Y, Behrends V, Letek M.

Sci Rep. 2019 Oct 28;9(1):15435. doi: 10.1038/s41598-019-51894-3.

4.

Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity.

Bravo-Santano N, Ellis JK, Calle Y, Keun HC, Behrends V, Letek M.

Metabolites. 2019 Jul 20;9(7). pii: E148. doi: 10.3390/metabo9070148.

5.

Host-directed kinase inhibitors act as novel therapies against intracellular Staphylococcus aureus.

Bravo-Santano N, Stölting H, Cooper F, Bileckaja N, Majstorovic A, Ihle N, Mateos LM, Calle Y, Behrends V, Letek M.

Sci Rep. 2019 Mar 19;9(1):4876. doi: 10.1038/s41598-019-41260-8.

6.

Repetitive Exposure of IL-17 Into the Murine Air Pouch Favors the Recruitment of Inflammatory Monocytes and the Release of IL-16 and TREM-1 in the Inflammatory Fluids.

Maione F, Iqbal AJ, Raucci F, Letek M, Bauer M, D'Acquisto F.

Front Immunol. 2018 Nov 30;9:2752. doi: 10.3389/fimmu.2018.02752. eCollection 2018.

7.

Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism.

Behrends V, Giskeødegård GF, Bravo-Santano N, Letek M, Keun HC.

Arch Toxicol. 2019 Feb;93(2):341-353. doi: 10.1007/s00204-018-2371-0. Epub 2018 Dec 14.

8.

Intracellular Staphylococcus aureus Modulates Host Central Carbon Metabolism To Activate Autophagy.

Bravo-Santano N, Ellis JK, Mateos LM, Calle Y, Keun HC, Behrends V, Letek M.

mSphere. 2018 Aug 8;3(4). pii: e00374-18. doi: 10.1128/mSphere.00374-18.

9.

The Arsenic Detoxification System in Corynebacteria: Basis and Application for Bioremediation and Redox Control.

Mateos LM, Villadangos AF, de la Rubia AG, Mourenza A, Marcos-Pascual L, Letek M, Pedre B, Messens J, Gil JA.

Adv Appl Microbiol. 2017;99:103-137. doi: 10.1016/bs.aambs.2017.01.001. Epub 2017 Mar 6. Review.

PMID:
28438267
10.

TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3.

Boada-Romero E, Letek M, Fleischer A, Pallauf K, Ramón-Barros C, Pimentel-Muiños FX.

EMBO J. 2013 Feb 20;32(4):566-82. doi: 10.1038/emboj.2013.8. Epub 2013 Feb 1.

11.

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.

Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, Kroemer G, Hetz C.

EMBO J. 2012 May 16;31(10):2322-35. doi: 10.1038/emboj.2012.84. Epub 2012 Apr 17.

12.

Cytoskeletal proteins of actinobacteria.

Letek M, Fiuza M, Villadangos AF, Mateos LM, Gil JA.

Int J Cell Biol. 2012;2012:905832. doi: 10.1155/2012/905832. Epub 2012 Feb 8.

13.

The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.

Letek M, González P, Macarthur I, Rodríguez H, Freeman TC, Valero-Rello A, Blanco M, Buckley T, Cherevach I, Fahey R, Hapeshi A, Holdstock J, Leadon D, Navas J, Ocampo A, Quail MA, Sanders M, Scortti MM, Prescott JF, Fogarty U, Meijer WG, Parkhill J, Bentley SD, Vázquez-Boland JA.

PLoS Genet. 2010 Sep 30;6(9):e1001145. doi: 10.1371/journal.pgen.1001145.

14.

Phosphorylation of a novel cytoskeletal protein (RsmP) regulates rod-shaped morphology in Corynebacterium glutamicum.

Fiuza M, Letek M, Leiba J, Villadangos AF, Vaquera J, Zanella-Cléon I, Mateos LM, Molle V, Gil JA.

J Biol Chem. 2010 Sep 17;285(38):29387-97. doi: 10.1074/jbc.M110.154427. Epub 2010 Jul 9.

15.

Domains involved in the in vivo function and oligomerization of apical growth determinant DivIVA in Streptomyces coelicolor.

Wang SB, Cantlay S, Nordberg N, Letek M, Gil JA, Flärdh K.

FEMS Microbiol Lett. 2009 Aug;297(1):101-9. doi: 10.1111/j.1574-6968.2009.01678.x. Epub 2009 Jun 5.

16.

DivIVA uses an N-terminal conserved region and two coiled-coil domains to localize and sustain the polar growth in Corynebacterium glutamicum.

Letek M, Fiuza M, Ordóñez E, Villadangos AF, Flärdh K, Mateos LM, Gil JA.

FEMS Microbiol Lett. 2009 Aug;297(1):110-6. doi: 10.1111/j.1574-6968.2009.01679.x. Epub 2009 Jun 5.

17.

Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.

Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J.

J Biol Chem. 2009 May 29;284(22):15107-16. doi: 10.1074/jbc.M900877200. Epub 2009 Mar 13.

18.

The MurC ligase essential for peptidoglycan biosynthesis is regulated by the serine/threonine protein kinase PknA in Corynebacterium glutamicum.

Fiuza M, Canova MJ, Patin D, Letek M, Zanella-Cléon I, Becchi M, Mateos LM, Mengin-Lecreulx D, Molle V, Gil JA.

J Biol Chem. 2008 Dec 26;283(52):36553-63. doi: 10.1074/jbc.M807175200. Epub 2008 Oct 29.

19.

Assemblies of DivIVA mark sites for hyphal branching and can establish new zones of cell wall growth in Streptomyces coelicolor.

Hempel AM, Wang SB, Letek M, Gil JA, Flärdh K.

J Bacteriol. 2008 Nov;190(22):7579-83. doi: 10.1128/JB.00839-08. Epub 2008 Sep 19.

20.

Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids.

Letek M, Ocampo-Sosa AA, Sanders M, Fogarty U, Buckley T, Leadon DP, González P, Scortti M, Meijer WG, Parkhill J, Bentley S, Vázquez-Boland JA.

J Bacteriol. 2008 Sep;190(17):5797-805. doi: 10.1128/JB.00468-08. Epub 2008 Jul 7.

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