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Items: 15

1.

Effect of the Structure of Therapeutic Adenosine Analogues on Stability and Surface Electrostatic Potential of their Complexes with Poly(propyleneimine) Dendrimers.

Gorzkiewicz M, Appelhans D, Boye S, Lederer A, Voit B, Klajnert-Maculewicz B.

Macromol Rapid Commun. 2019 May 28:e1900181. doi: 10.1002/marc.201900181. [Epub ahead of print]

PMID:
31136015
2.

Fludarabine-Specific Molecular Interactions with Maltose-Modified Poly(propyleneimine) Dendrimer Enable Effective Cell Entry of the Active Drug Form: Comparison with Clofarabine.

Gorzkiewicz M, Deriu MA, Studzian M, Janaszewska A, Grasso G, Pułaski Ł, Appelhans D, Danani A, Klajnert-Maculewicz B.

Biomacromolecules. 2019 Mar 11;20(3):1429-1442. doi: 10.1021/acs.biomac.9b00010. Epub 2019 Feb 18.

PMID:
30707833
3.

Gold Nanoparticles in Cancer Treatment.

Sztandera K, Gorzkiewicz M, Klajnert-Maculewicz B.

Mol Pharm. 2019 Jan 7;16(1):1-23. doi: 10.1021/acs.molpharmaceut.8b00810. Epub 2018 Nov 30.

PMID:
30452861
4.

Complexes of Indomethacin with 4-Carbomethoxy-pyrrolidone PAMAM Dendrimers Show Improved Anti-inflammatory Properties and Temperature-Dependent Binding and Release Profile.

Ficker M, Theeuwen MJM, Janaszewska A, Gorzkiewicz M, Svenningsen SW, Klajnert-Maculewicz B, Christensen JB.

Mol Pharm. 2018 Aug 6;15(8):3573-3582. doi: 10.1021/acs.molpharmaceut.8b00567. Epub 2018 Jul 25.

PMID:
30011214
5.

Poly(propyleneimine) glycodendrimers non-covalently bind ATP in a pH- and salt-dependent manner - model studies for adenosine analogue drug delivery.

Gorzkiewicz M, Buczkowski A, Appelhans D, Voit B, Pułaski Ł, Pałecz B, Klajnert-Maculewicz B.

Int J Pharm. 2018 Jun 10;544(1):83-90. doi: 10.1016/j.ijpharm.2018.03.063. Epub 2018 Apr 10.

PMID:
29653214
6.

Terminal Sugar Moiety Determines Immunomodulatory Properties of Poly(propyleneimine) Glycodendrimers.

Gorzkiewicz M, Sztandera K, Jatczak-Pawlik I, Zinke R, Appelhans D, Klajnert-Maculewicz B, Pulaski Ł.

Biomacromolecules. 2018 May 14;19(5):1562-1572. doi: 10.1021/acs.biomac.8b00168. Epub 2018 Apr 3.

PMID:
29569917
7.

Glycodendrimer Nanocarriers for Direct Delivery of Fludarabine Triphosphate to Leukemic Cells: Improved Pharmacokinetics and Pharmacodynamics of Fludarabine.

Gorzkiewicz M, Jatczak-Pawlik I, Studzian M, Pułaski Ł, Appelhans D, Voit B, Klajnert-Maculewicz B.

Biomacromolecules. 2018 Feb 12;19(2):531-543. doi: 10.1021/acs.biomac.7b01650. Epub 2018 Jan 30.

PMID:
29323872
8.

Pyrrolidone Modification Prevents PAMAM Dendrimers from Activation of Pro-Inflammatory Signaling Pathways in Human Monocytes.

Janaszewska A, Gorzkiewicz M, Ficker M, Petersen JF, Paolucci V, Christensen JB, Klajnert-Maculewicz B.

Mol Pharm. 2018 Jan 2;15(1):12-20. doi: 10.1021/acs.molpharmaceut.7b00515. Epub 2017 Dec 14.

PMID:
29191014
9.

TLR2 activation induces antioxidant defence in human monocyte-macrophage cell line models.

Karwaciak I, Gorzkiewicz M, Bartosz G, Pulaski L.

Oncotarget. 2017 Apr 21;8(33):54243-54264. doi: 10.18632/oncotarget.17342. eCollection 2017 Aug 15.

10.

Dendrimers as nanocarriers for nucleoside analogues.

Gorzkiewicz M, Klajnert-Maculewicz B.

Eur J Pharm Biopharm. 2017 May;114:43-56. doi: 10.1016/j.ejpb.2016.12.030. Epub 2017 Jan 13. Review.

PMID:
28089915
11.

Towards Engineering Novel PE-Based Immunotoxins by Targeting Them to the Nucleus.

Borowiec M, Gorzkiewicz M, Grzesik J, Walczak-Drzewiecka A, Salkowska A, Rodakowska E, Steczkiewicz K, Rychlewski L, Dastych J, Ginalski K.

Toxins (Basel). 2016 Nov 10;8(11). pii: E321.

12.

Expression of human gene coding RORγT receptor depends on the Sp2 transcription factor.

Ratajewski M, Walczak-Drzewiecka A, Gorzkiewicz M, Sałkowska A, Dastych J.

J Leukoc Biol. 2016 Nov;100(5):1213-1223. Epub 2016 Jun 2.

PMID:
27256574
13.

Sugar-Modified Poly(propylene imine) Dendrimers Stimulate the NF-κB Pathway in a Myeloid Cell Line.

Jatczak-Pawlik I, Gorzkiewicz M, Studzian M, Appelhans D, Voit B, Pulaski L, Klajnert-Maculewicz B.

Pharm Res. 2017 Jan;34(1):136-147. doi: 10.1007/s11095-016-2049-3. Epub 2016 Oct 20.

14.

AC-93253 triggers the downregulation of melanoma progression markers and the inhibition of melanoma cell proliferation.

Karwaciak I, Gorzkiewicz M, Ryba K, Dastych J, Pulaski L, Ratajewski M.

Chem Biol Interact. 2015 Jul 5;236:9-18. doi: 10.1016/j.cbi.2015.04.016. Epub 2015 Apr 23.

PMID:
25912555
15.

Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.

Ratajewski M, Grzelak I, Wiśniewska K, Ryba K, Gorzkiewicz M, Walczak-Drzewiecka A, Hoffmann M, Dastych J.

Toxicol Lett. 2015 Jan 5;232(1):193-202. doi: 10.1016/j.toxlet.2014.10.009. Epub 2014 Oct 16.

PMID:
25455453

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