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Items: 1 to 20 of 46

1.

Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.

Zhao W, Bohleber S, Schmidt H, Seeher S, Howard MT, Braun D, Arndt S, Reuter U, Wende H, Birchmeier C, Fradejas-Villar N, Schweizer U.

J Biol Chem. 2019 Sep 27;294(39):14185-14200. doi: 10.1074/jbc.RA119.009369. Epub 2019 Jul 26.

2.

New Directions for Understanding the Codon Redefinition Required for Selenocysteine Incorporation.

Howard MT, Copeland PR.

Biol Trace Elem Res. 2019 Nov;192(1):18-25. doi: 10.1007/s12011-019-01827-y. Epub 2019 Jul 24.

PMID:
31342342
3.

Disuse-induced insulin resistance susceptibility coincides with a dysregulated skeletal muscle metabolic transcriptome.

Mahmassani ZS, Reidy PT, McKenzie AI, Stubben C, Howard MT, Drummond MJ.

J Appl Physiol (1985). 2019 May 1;126(5):1419-1429. doi: 10.1152/japplphysiol.01093.2018. Epub 2019 Feb 14.

PMID:
30763167
4.

Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.

Mahmassani ZS, Reidy PT, McKenzie AI, Stubben C, Howard MT, Drummond MJ.

J Appl Physiol (1985). 2019 Apr 1;126(4):894-902. doi: 10.1152/japplphysiol.00811.2018. Epub 2019 Jan 3.

PMID:
30605403
5.

Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein P.

Mariotti M, Shetty S, Baird L, Wu S, Loughran G, Copeland PR, Atkins JF, Howard MT.

Nucleic Acids Res. 2017 Dec 15;45(22):13004-13015. doi: 10.1093/nar/gkx982.

6.

Evaluation of Third-Party Deep Cleaning as a Listeria monocytogenes Control Strategy in Retail Delis.

Hammons SR, Etter AJ, Wang J, Wu T, Ford T, Howard MT, Oliver HF.

J Food Prot. 2017 Oct 20:1913-1923. doi: 10.4315/0362-028X.JFP-17-113. [Epub ahead of print]

PMID:
29053422
7.

Studying Selenoprotein mRNA Translation Using RNA-Seq and Ribosome Profiling.

Dalley BK, Baird L, Howard MT.

Methods Mol Biol. 2018;1661:103-123. doi: 10.1007/978-1-4939-7258-6_8.

PMID:
28917040
8.

Leucine Differentially Regulates Gene-Specific Translation in Mouse Skeletal Muscle.

Drummond MJ, Reidy PT, Baird LM, Dalley BK, Howard MT.

J Nutr. 2017 Sep;147(9):1616-1623. doi: 10.3945/jn.117.251181. Epub 2017 Jun 14.

9.

Avoidance of reporter assay distortions from fused dual reporters.

Loughran G, Howard MT, Firth AE, Atkins JF.

RNA. 2017 Aug;23(8):1285-1289. doi: 10.1261/rna.061051.117. Epub 2017 Apr 25.

10.

The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay.

Fradejas-Villar N, Seeher S, Anderson CB, Doengi M, Carlson BA, Hatfield DL, Schweizer U, Howard MT.

Nucleic Acids Res. 2017 Apr 20;45(7):4094-4107. doi: 10.1093/nar/gkw1255.

11.

Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements.

Wu S, Mariotti M, Santesmasses D, Hill KE, Baclaocos J, Aparicio-Prat E, Li S, Mackrill J, Wu Y, Howard MT, Capecchi M, Guigó R, Burk RF, Atkins JF.

Open Biol. 2016 Nov;6(11). pii: 160241.

12.

Association Study of Exon Variants in the NF-κB and TGFβ Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy.

Bello L, Flanigan KM, Weiss RB; United Dystrophinopathy Project, Spitali P, Aartsma-Rus A, Muntoni F, Zaharieva I, Ferlini A, Mercuri E, Tuffery-Giraud S, Claustres M, Straub V, Lochmüller H, Barp A, Vianello S, Pegoraro E, Punetha J, Gordish-Dressman H, Giri M, McDonald CM, Hoffman EP; Cooperative International Neuromuscular Research Group.

Am J Hum Genet. 2016 Nov 3;99(5):1163-1171. doi: 10.1016/j.ajhg.2016.08.023. Epub 2016 Oct 13.

13.

Selenoprotein Gene Nomenclature.

Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, Green FR, Guigó R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, Köhrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonović M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y.

J Biol Chem. 2016 Nov 11;291(46):24036-24040. Epub 2016 Sep 19.

14.

Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice.

Tsuji PA, Carlson BA, Anderson CB, Seifried HE, Hatfield DL, Howard MT.

Nutrients. 2015 Aug 6;7(8):6529-49. doi: 10.3390/nu7085297.

15.

Corrigendum: Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.

Wein N, Vulin A, Falzarano MS, Szigyarto CA, Maiti B, Findlay A, Heller KN, Uhlén M, Bakthavachalu B, Messina S, Vita G, Passarelli C, Brioschi S, Bovolenta M, Neri M, Gualandi F, Wilton SD, Rodino-Klapac LR, Yang L, Dunn DM, Schoenberg DR, Weiss RB, Howard MT, Ferlini A, Flanigan KM.

Nat Med. 2015 May;21(5):537. doi: 10.1038/nm0515-537c. No abstract available.

PMID:
25951531
16.

Corrigendum: Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.

Wein N, Vulin A, Falzarano MS, Szigyarto CA, Maiti B, Findlay A, Heller KN, Uhlén M, Bakthavachalu B, Messina S, Vita G, Passarelli C, Gualandi F, Wilton SD, Rodino-Klapac LR, Yang L, Dunn DM, Schoenberg DR, Weiss RB, Howard MT, Ferlini A, Flanigan KM.

Nat Med. 2015 Apr;21(4):414. doi: 10.1038/nm0415-414b. No abstract available.

PMID:
25849273
17.

Clinical phenotypes as predictors of the outcome of skipping around DMD exon 45.

Findlay AR, Wein N, Kaminoh Y, Taylor LE, Dunn DM, Mendell JR, King WM, Pestronk A, Florence JM, Mathews KD, Finkel RS, Swoboda KJ, Howard MT, Day JW, McDonald C, Nicolas A, Le Rumeur E, Weiss RB, Flanigan KM; United Dystrophinopathy Project.

Ann Neurol. 2015 Apr;77(4):668-74. doi: 10.1002/ana.24365. Epub 2015 Mar 2.

18.

Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.

Wein N, Vulin A, Falzarano MS, Szigyarto CA, Maiti B, Findlay A, Heller KN, Uhlén M, Bakthavachalu B, Messina S, Vita G, Passarelli C, Brioschi S, Bovolenta M, Neri M, Gualandi F, Wilton SD, Rodino-Klapac LR, Yang L, Dunn DM, Schoenberg DR, Weiss RB, Howard MT, Ferlini A, Flanigan KM.

Nat Med. 2014 Sep;20(9):992-1000. doi: 10.1038/nm.3628. Epub 2014 Aug 10. Erratum in: Nat Med. 2015 Apr;21(4):414. Nat Med. 2015 May;21(5):537. Brioschi, Simona [added]; Bovolenta, Matteo [added]; Neri, Marcella [added].

19.

Conserved regions of the DMD 3' UTR regulate translation and mRNA abundance in cultured myotubes.

Larsen CA, Howard MT.

Neuromuscul Disord. 2014 Aug;24(8):693-706. doi: 10.1016/j.nmd.2014.05.006. Epub 2014 May 22.

20.

Cryptic MHC class I-binding peptides are revealed by aminoglycoside-induced stop codon read-through into the 3' UTR.

Goodenough E, Robinson TM, Zook MB, Flanigan KM, Atkins JF, Howard MT, Eisenlohr LC.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5670-5. doi: 10.1073/pnas.1402670111. Epub 2014 Mar 31.

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