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Items: 1 to 20 of 141

1.

Genome-wide effects of social status on DNA methylation in the brain of a cichlid fish, Astatotilapia burtoni.

Hilliard AT, Xie D, Ma Z, Snyder MP, Fernald RD.

BMC Genomics. 2019 Sep 11;20(1):699. doi: 10.1186/s12864-019-6047-9.

2.

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.

Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, Phanstiel DH, Snyder MP, Bintu L, Greenleaf WJ, Kundaje A, Bassik MC.

Nat Commun. 2019 Sep 6;10(1):4063. doi: 10.1038/s41467-019-11955-7.

3.

Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation.

Tian W, Jiang X, Sung YK, Shuffle E, Wu TH, Kao PN, Tu AB, Dorfmüller P, Cao A, Wang L, Peng G, Kim Y, Zhang P, Chappell J, Pasupneti S, Dahms P, Maguire P, Chaib H, Zamanian R, Peters-Golden M, Snyder MP, Voelkel NF, Humbert M, Rabinovitch M, Nicolls MR.

Circulation. 2019 Aug 29. doi: 10.1161/CIRCULATIONAHA.119.040629. [Epub ahead of print]

PMID:
31462075
4.

Chromatin Remodeling in Response to BRCA2-Crisis.

Gruber JJ, Chen J, Geller B, Jäger N, Lipchik AM, Wang G, Kurian AW, Ford JM, Snyder MP.

Cell Rep. 2019 Aug 20;28(8):2182-2193.e6. doi: 10.1016/j.celrep.2019.07.057.

5.

Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project.

Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Pennington S, Snyder MP, Baker MS, Deutsch EW.

J Proteome Res. 2019 Sep 13. doi: 10.1021/acs.jproteome.9b00434. [Epub ahead of print]

PMID:
31430157
6.

Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes.

Sberro H, Fremin BJ, Zlitni S, Edfors F, Greenfield N, Snyder MP, Pavlopoulos GA, Kyrpides NC, Bhatt AS.

Cell. 2019 Aug 22;178(5):1245-1259.e14. doi: 10.1016/j.cell.2019.07.016. Epub 2019 Aug 8.

PMID:
31402174
7.

Simultaneous RNA purification and size selection using on-chip isotachophoresis with an ionic spacer.

Han CM, Catoe D, Munro SA, Khnouf R, Snyder MP, Santiago JG, Salit ML, Cenik C.

Lab Chip. 2019 Aug 21;19(16):2741-2749. doi: 10.1039/c9lc00311h. Epub 2019 Jul 22.

PMID:
31328753
8.

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.

Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, Rhee JW, Churko JM, Chaudhary R, Chour T, Wang PJ, Snyder MP, Chang HY, Karakikes I, Wu JC.

Nature. 2019 Aug;572(7769):335-340. doi: 10.1038/s41586-019-1406-x. Epub 2019 Jul 17.

PMID:
31316208
9.

Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility.

Stowers RS, Shcherbina A, Israeli J, Gruber JJ, Chang J, Nam S, Rabiee A, Teruel MN, Snyder MP, Kundaje A, Chaudhuri O.

Nat Biomed Eng. 2019 Jul 8. doi: 10.1038/s41551-019-0420-5. [Epub ahead of print]

PMID:
31285581
10.

HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding.

Gruber JJ, Geller B, Lipchik AM, Chen J, Salahudeen AA, Ram AN, Ford JM, Kuo CJ, Snyder MP.

Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034. Epub 2019 Jul 2.

PMID:
31278053
11.

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, Cavalli FMG, Luu B, Moriarity BS, Ilkhanizadeh S, Chavez L, Yu C, Kurian KM, Magnaldo T, Sevenet N, Koch P, Pollard SM, Dirks P, Snyder MP, Largaespada DA, Cho YJ, Phillips JJ, Swartling FJ, Morrissy AS, Kool M, Pfister SM, Taylor MD, Smith A, Weiss WA.

Cell Stem Cell. 2019 Sep 5;25(3):433-446.e7. doi: 10.1016/j.stem.2019.05.013. Epub 2019 Jun 13.

12.

High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients.

Chen J, Haanpää MK, Gruber JJ, Jäger N, Ford JM, Snyder MP.

Clin Cancer Res. 2019 Sep 1;25(17):5301-5314. doi: 10.1158/1078-0432.CCR-18-2423. Epub 2019 Jun 7.

PMID:
31175093
13.

The Integrative Human Microbiome Project.

Integrative HMP (iHMP) Research Network Consortium.

Nature. 2019 May;569(7758):641-648. doi: 10.1038/s41586-019-1238-8. Epub 2019 May 29. Review.

PMID:
31142853
14.

Personalized Metabolomics.

Marciano DP, Snyder MP.

Methods Mol Biol. 2019;1978:447-456. doi: 10.1007/978-1-4939-9236-2_27.

PMID:
31119679
15.

A longitudinal big data approach for precision health.

Schüssler-Fiorenza Rose SM, Contrepois K, Moneghetti KJ, Zhou W, Mishra T, Mataraso S, Dagan-Rosenfeld O, Ganz AB, Dunn J, Hornburg D, Rego S, Perelman D, Ahadi S, Sailani MR, Zhou Y, Leopold SR, Chen J, Ashland M, Christle JW, Avina M, Limcaoco P, Ruiz C, Tan M, Butte AJ, Weinstock GM, Slavich GM, Sodergren E, McLaughlin TL, Haddad F, Snyder MP.

Nat Med. 2019 May;25(5):792-804. doi: 10.1038/s41591-019-0414-6. Epub 2019 May 8.

PMID:
31068711
16.

Author Correction: Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis.

Fotiou E, Martin-Almedina S, Simpson MA, Lin S, Gordon K, Brice G, Atton G, Jeffery I, Rees DC, Mignot C, Vogt J, Homfray T, Snyder MP, Rockson SG, Jeffery S, Mortimer PS, Mansour S, Ostergaard P.

Nat Commun. 2019 Apr 26;10(1):1951. doi: 10.1038/s41467-019-09905-4.

17.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
18.

Much ado about nothing: A qualitative study of the experiences of an average-risk population receiving results of exome sequencing.

Rego S, Dagan-Rosenfeld O, Bivona SA, Snyder MP, Ormond KE.

J Genet Couns. 2019 Apr;28(2):428-437. doi: 10.1002/jgc4.1096. Epub 2019 Mar 5.

PMID:
30835913
19.

Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle.

Sailani MR, Halling JF, Møller HD, Lee H, Plomgaard P, Pilegaard H, Snyder MP, Regenberg B.

Sci Rep. 2019 Mar 1;9(1):3272. doi: 10.1038/s41598-018-37895-8.

20.

2017 NIH-wide workshop report on "The Human Microbiome: Emerging Themes at the Horizon of the 21st Century".

2017 NIH-wide microbiome workshop writing team.

Microbiome. 2019 Feb 26;7(1):32. doi: 10.1186/s40168-019-0627-4.

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