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Pseudomonas aeruginosa AlgR Phosphorylation Status Differentially Regulates Pyocyanin and Pyoverdine Production.

Little AS, Okkotsu Y, Reinhart AA, Damron FH, Barbier M, Barrett B, Oglesby-Sherrouse AG, Goldberg JB, Cody WL, Schurr MJ, Vasil ML, Schurr MJ.

MBio. 2018 Jan 30;9(1). pii: e02318-17. doi: 10.1128/mBio.02318-17.


Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct.

Grøftehauge MK, Truan D, Vasil A, Denny PW, Vasil ML, Pohl E.

Int J Mol Sci. 2015 Jul 14;16(7):15971-84. doi: 10.3390/ijms160715971.


Corrigendum to "High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa" [Protein Expr. Purif. 90 (2013) 40-46].

Truan D, Vasil A, Stonehouse M, Vasil ML, Pohl E.

Protein Expr Purif. 2015 Apr;108:115. doi: 10.1016/j.pep.2014.08.008. Epub 2014 Aug 15. No abstract available.


Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa.

Wiens JR, Vasil AI, Schurr MJ, Vasil ML.

MBio. 2014 Feb 4;5(1):e01010-13. doi: 10.1128/mBio.01010-13.


The complex interplay of iron, biofilm formation, and mucoidy affecting antimicrobial resistance of Pseudomonas aeruginosa.

Oglesby-Sherrouse AG, Djapgne L, Nguyen AT, Vasil AI, Vasil ML.

Pathog Dis. 2014 Apr;70(3):307-20. doi: 10.1111/2049-632X.12132. Epub 2014 Feb 10.


Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers.

Ibarguren M, Sot J, Montes LR, Vasil AI, Vasil ML, Goñi FM, Alonso A.

Chem Phys Lipids. 2013 Jan;166:12-7. doi: 10.1016/j.chemphyslip.2012.12.001. Epub 2012 Dec 17.


High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.

Truan D, Vasil A, Stonehouse M, Vasil ML, Pohl E.

Protein Expr Purif. 2013 Jul;90(1):40-6. doi: 10.1016/j.pep.2012.11.005. Epub 2012 Nov 29. Erratum in: Protein Expr Purif. 2015 Apr;108:115.


Identification and evaluation of twin-arginine translocase inhibitors.

Vasil ML, Tomaras AP, Pritchard AE.

Antimicrob Agents Chemother. 2012 Dec;56(12):6223-34. doi: 10.1128/AAC.01575-12. Epub 2012 Sep 24.


Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

Young RL, Malcolm KC, Kret JE, Caceres SM, Poch KR, Nichols DP, Taylor-Cousar JL, Saavedra MT, Randell SH, Vasil ML, Burns JL, Moskowitz SM, Nick JA.

PLoS One. 2011;6(9):e23637. doi: 10.1371/journal.pone.0023637. Epub 2011 Sep 1.


The lipase LipA (PA2862) but not LipC (PA4813) from Pseudomonas aeruginosa influences regulation of pyoverdine production and expression of the sigma factor PvdS.

Funken H, Knapp A, Vasil ML, Wilhelm S, Jaeger KE, Rosenau F.

J Bacteriol. 2011 Oct;193(20):5858-60. doi: 10.1128/JB.05765-11. Epub 2011 Aug 12.


Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei.

Rholl DA, Papp-Wallace KM, Tomaras AP, Vasil ML, Bonomo RA, Schweizer HP.

Front Microbiol. 2011 Jul 1;2:139. doi: 10.3389/fmicb.2011.00139. eCollection 2011.


Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection.

Wargo MJ, Gross MJ, Rajamani S, Allard JL, Lundblad LK, Allen GB, Vasil ML, Leclair LW, Hogan DA.

Am J Respir Crit Care Med. 2011 Aug 1;184(3):345-54. doi: 10.1164/rccm.201103-0374OC. Epub 2011 May 11.


Imaging the early stages of phospholipase C/sphingomyelinase activity on vesicles containing coexisting ordered-disordered and gel-fluid domains.

Ibarguren M, López DJ, Montes LR, Sot J, Vasil AI, Vasil ML, Goñi FM, Alonso A.

J Lipid Res. 2011 Apr;52(4):635-45. doi: 10.1194/jlr.M012591. Epub 2011 Jan 20.


Multiple phospholipid substrates of phospholipase C/sphingomyelinase HR2 from Pseudomonas aeruginosa.

López DJ, Collado MI, Ibarguren M, Vasil AI, Vasil ML, Goñi FM, Alonso A.

Chem Phys Lipids. 2011 Jan;164(1):78-82. doi: 10.1016/j.chemphyslip.2010.11.001. Epub 2010 Nov 10.


Characterization of a heme-regulated non-coding RNA encoded by the prrF locus of Pseudomonas aeruginosa.

Oglesby-Sherrouse AG, Vasil ML.

PLoS One. 2010 Apr 8;5(4):e9930. doi: 10.1371/journal.pone.0009930.


End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.

Ibarguren M, Bomans PH, Frederik PM, Stonehouse M, Vasil AI, Vasil ML, Alonso A, Goñi FM.

Biochim Biophys Acta. 2010 Jan;1798(1):59-64. doi: 10.1016/j.bbamem.2009.10.017. Epub 2009 Nov 3.


A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells.

Vasil ML, Stonehouse MJ, Vasil AI, Wadsworth SJ, Goldfine H, Bolcome RE 3rd, Chan J.

PLoS Pathog. 2009 May;5(5):e1000420. doi: 10.1371/journal.ppat.1000420. Epub 2009 May 8.


Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.

Jiang Z, Vasil AI, Hale J, Hancock RE, Vasil ML, Hodges RS.

Adv Exp Med Biol. 2009;611:561-2. No abstract available.


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