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Items: 1 to 20 of 159


Tricellulin Effect on Paracellular Water Transport.

Ayala-Torres C, Krug SM, Schulzke JD, Rosenthal R, Fromm M.

Int J Mol Sci. 2019 Nov 14;20(22). pii: E5700. doi: 10.3390/ijms20225700.


Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment.

Hering NA, Fromm A, Bücker R, Gorkiewicz G, Zechner E, Högenauer C, Fromm M, Schulzke JD, Troeger H.

Int J Mol Sci. 2019 Nov 8;20(22). pii: E5595. doi: 10.3390/ijms20225595.


Potential for Tight Junction Protein-Directed Drug Development Using Claudin Binders and Angubindin-1.

Hashimoto Y, Tachibana K, Krug SM, Kunisawa J, Fromm M, Kondoh M.

Int J Mol Sci. 2019 Aug 17;20(16). pii: E4016. doi: 10.3390/ijms20164016. Review.


Black carbon lofts wildfire smoke high into the stratosphere to form a persistent plume.

Yu P, Toon OB, Bardeen CG, Zhu Y, Rosenlof KH, Portmann RW, Thornberry TD, Gao RS, Davis SM, Wolf ET, de Gouw J, Peterson DA, Fromm MD, Robock A.

Science. 2019 Aug 9;365(6453):587-590. doi: 10.1126/science.aax1748.


Store-operated calcium entry (SOCE) contributes to phosphorylation of p38 MAPK and suppression of TNF-α signalling in the intestinal epithelial cells.

Uwada J, Yazawa T, Nakazawa H, Mikami D, Krug SM, Fromm M, Sada K, Muramatsu I, Taniguchi T.

Cell Signal. 2019 Nov;63:109358. doi: 10.1016/j.cellsig.2019.109358. Epub 2019 Jul 8.


Claudin-15 forms a water channel through the tight junction with distinct function compared to claudin-2.

Rosenthal R, Günzel D, Piontek J, Krug SM, Ayala-Torres C, Hempel C, Theune D, Fromm M.

Acta Physiol (Oxf). 2020 Jan;228(1):e13334. doi: 10.1111/apha.13334. Epub 2019 Jul 8.


Phospholipid effects on SGLT1-mediated glucose transport in rabbit ileum brush border membrane vesicles.

Ebel H, Fromm A, Günzel D, Fromm M, Schulzke JD.

Biochim Biophys Acta Biomembr. 2019 Oct 1;1861(10):182985. doi: 10.1016/j.bbamem.2019.05.007. Epub 2019 May 11.


Tissue plasminogen activator and neuropathy open the blood-nerve barrier with upregulation of microRNA-155-5p in male rats.

Reinhold AK, Yang S, Chen JT, Hu L, Sauer RS, Krug SM, Mambretti EM, Fromm M, Brack A, Rittner HL.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1160-1169. doi: 10.1016/j.bbadis.2019.01.008. Epub 2019 Jan 6.


Dehydration Stress Memory: Gene Networks Linked to Physiological Responses During Repeated Stresses of Zea mays.

Virlouvet L, Avenson TJ, Du Q, Zhang C, Liu N, Fromm M, Avramova Z, Russo SE.

Front Plant Sci. 2018 Jul 24;9:1058. doi: 10.3389/fpls.2018.01058. eCollection 2018.


Gelatinolytic activity of autocrine matrix metalloproteinase-9 leads to endothelial de-arrangement in Moyamoya disease.

Blecharz-Lang KG, Prinz V, Burek M, Frey D, Schenkel T, Krug SM, Fromm M, Vajkoczy P.

J Cereb Blood Flow Metab. 2018 Nov;38(11):1940-1953. doi: 10.1177/0271678X18768443. Epub 2018 Apr 10.


Epithelial barrier dysfunction as permissive pathomechanism in human intestinal graft-versus-host disease.

Troeger H, Hering NA, Bojarski C, Fromm A, Barmeyer C, Uharek L, Siegmund B, Fromm M, Rieger K, Schulzke JD.

Bone Marrow Transplant. 2018 Aug;53(8):1083-1086. doi: 10.1038/s41409-018-0144-2. Epub 2018 Mar 9. No abstract available.


A cytochrome P450 CYP71 enzyme expressed in Sorghum bicolor root hair cells participates in the biosynthesis of the benzoquinone allelochemical sorgoleone.

Pan Z, Baerson SR, Wang M, Bajsa-Hirschel J, Rimando AM, Wang X, Nanayakkara NPD, Noonan BP, Fromm ME, Dayan FE, Khan IA, Duke SO.

New Phytol. 2018 Apr;218(2):616-629. doi: 10.1111/nph.15037. Epub 2018 Feb 20.


Wildfire-driven thunderstorms cause a volcano-like stratospheric injection of smoke.

Peterson DA, Campbell JR, Hyer EJ, Fromm MD, Kablick GP 3rd, Cossuth JH, DeLand MT.

NPJ Clim Atmos Sci. 2018;1. doi: 10.1038/s41612-018-0039-3. Epub 2018 Aug 20.


In Colon Epithelia, Clostridium perfringens Enterotoxin Causes Focal Leaks by Targeting Claudins Which are Apically Accessible Due to Tight Junction Derangement.

Eichner M, Augustin C, Fromm A, Piontek A, Walther W, Bücker R, Fromm M, Krause G, Schulzke JD, Günzel D, Piontek J.

J Infect Dis. 2017 Dec 27;217(1):147-157. doi: 10.1093/infdis/jix485.


Zinc strengthens the jejunal barrier by reversibly tightening the paracellular route.

Zakrzewski SS, Fromm M, Schulzke JD, Günzel D.

Am J Physiol Gastrointest Liver Physiol. 2017 Dec 1;313(6):G537-G548. doi: 10.1152/ajpgi.00355.2016. Epub 2017 Sep 1.


Campylobacter fetus impairs barrier function in HT-29/B6 cells through focal tight junction alterations and leaks.

Bücker R, Krug SM, Fromm A, Nielsen HL, Fromm M, Nielsen H, Schulzke JD.

Ann N Y Acad Sci. 2017 Oct;1405(1):189-201. doi: 10.1111/nyas.13406. Epub 2017 Jun 29.


Water channels and barriers formed by claudins.

Rosenthal R, Günzel D, Theune D, Czichos C, Schulzke JD, Fromm M.

Ann N Y Acad Sci. 2017 Jun;1397(1):100-109. doi: 10.1111/nyas.13383. Review.


Tight junctions of the proximal tubule and their channel proteins.

Fromm M, Piontek J, Rosenthal R, Günzel D, Krug SM.

Pflugers Arch. 2017 Aug;469(7-8):877-887. doi: 10.1007/s00424-017-2001-3. Epub 2017 Jun 9. Review.


Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction.

Krug SM, Hayaishi T, Iguchi D, Watari A, Takahashi A, Fromm M, Nagahama M, Takeda H, Okada Y, Sawasaki T, Doi T, Yagi K, Kondoh M.

J Control Release. 2017 Aug 28;260:1-11. doi: 10.1016/j.jconrel.2017.05.024. Epub 2017 May 18.


Activation of muscarinic receptors prevents TNF-α-mediated intestinal epithelial barrier disruption through p38 MAPK.

Uwada J, Yazawa T, Islam MT, Khan MRI, Krug SM, Fromm M, Karaki SI, Suzuki Y, Kuwahara A, Yoshiki H, Sada K, Muramatsu I, Taniguchi T.

Cell Signal. 2017 Jul;35:188-196. doi: 10.1016/j.cellsig.2017.04.007. Epub 2017 Apr 12.


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