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Items: 1 to 20 of 32


Effect of Different Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins.

Akache B, Deschatelets L, Harrison BA, Dudani R, Stark FC, Jia Y, Landi A, Law JLM, Logan M, Hockman D, Kundu J, Tyrrell DL, Krishnan L, Houghton M, McCluskie MJ.

Vaccines (Basel). 2019 Dec 3;7(4). pii: E204. doi: 10.3390/vaccines7040204.


Simplified Admix Archaeal Glycolipid Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Enhances Protection from Murine Melanoma.

Stark FC, Agbayani G, Sandhu JK, Akache B, McPherson C, Deschatelets L, Dudani R, Hewitt M, Jia Y, Krishnan L, McCluskie MJ.

Biomedicines. 2019 Nov 23;7(4). pii: E91. doi: 10.3390/biomedicines7040091.


Evaluation of recombinant adenovirus vectors and adjuvanted protein as a heterologous prime-boost strategy using HER2 as a model antigen.

Haq K, Jia Y, Elahi SM, MacLean S, Akache B, Gurnani K, Chattopadhyay A, Nazemi-Moghaddam N, Gilbert R, McCluskie MJ, Weeratna RD.

Vaccine. 2019 Nov 8;37(47):7029-7040. doi: 10.1016/j.vaccine.2019.08.079. Epub 2019 Sep 7.


Archaeal glycolipid adjuvanted vaccines induce strong influenza-specific immune responses through direct immunization in young and aged mice or through passive maternal immunization.

Stark FC, Akache B, Ponce A, Dudani R, Deschatelets L, Jia Y, Sauvageau J, Williams D, Jamshidi MP, Agbayani G, Wachholz K, Harrison BA, Li X, Krishnan L, Chen W, McCluskie MJ.

Vaccine. 2019 Nov 8;37(47):7108-7116. doi: 10.1016/j.vaccine.2019.07.010. Epub 2019 Aug 2.


A comparison of the immune responses induced by antigens in three different archaeosome-based vaccine formulations.

Jia Y, Akache B, Deschatelets L, Qian H, Dudani R, Harrison BA, Stark FC, Chandan V, Jamshidi MP, Krishnan L, McCluskie MJ.

Int J Pharm. 2019 Apr 20;561:187-196. doi: 10.1016/j.ijpharm.2019.02.041. Epub 2019 Mar 2.


Sulfated archaeol glycolipids: Comparison with other immunological adjuvants in mice.

Akache B, Stark FC, Jia Y, Deschatelets L, Dudani R, Harrison BA, Agbayani G, Williams D, Jamshidi MP, Krishnan L, McCluskie MJ.

PLoS One. 2018 Dec 4;13(12):e0208067. doi: 10.1371/journal.pone.0208067. eCollection 2018.


Safety and biodistribution of sulfated archaeal glycolipid archaeosomes as vaccine adjuvants.

Akache B, Stark FC, Iqbal U, Chen W, Jia Y, Krishnan L, McCluskie MJ.

Hum Vaccin Immunother. 2018 Jul 3;14(7):1746-1759. doi: 10.1080/21645515.2017.1423154. Epub 2018 Jan 30.


An Archaeosome-Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Significantly Enhances Protection from Murine Melanoma.

Stark FC, Weeratna RD, Deschatelets L, Gurnani K, Dudani R, McCluskie MJ, Krishnan L.

Vaccines (Basel). 2017 Oct 26;5(4). pii: E38. doi: 10.3390/vaccines5040038.


In vitro evaluation of archaeosome vehicles for transdermal vaccine delivery.

Jia Y, McCluskie MJ, Zhang D, Monette R, Iqbal U, Moreno M, Sauvageau J, Williams D, Deschatelets L, Jakubek ZJ, Krishnan L.

J Liposome Res. 2018 Dec;28(4):305-314. doi: 10.1080/08982104.2017.1376683. Epub 2017 Sep 26.


Sulfated archaeal glycolipid archaeosomes as a safe and effective vaccine adjuvant for induction of cell-mediated immunity.

McCluskie MJ, Deschatelets L, Krishnan L.

Hum Vaccin Immunother. 2017 Dec 2;13(12):2772-2779. doi: 10.1080/21645515.2017.1316912. Epub 2017 May 24.


The Effect of Physicochemical Modification on the Function of Antibodies Induced by Anti-Nicotine Vaccine in Mice.

Thorn JM, Bhattacharya K, Crutcher R, Sperry J, Isele C, Kelly B, Yates L, Zobel J, Zhang N, Davis HL, McCluskie MJ.

Vaccines (Basel). 2017 May 17;5(2). pii: E11. doi: 10.3390/vaccines5020011.


Immunogenicity of a peptide-based anti-IgE conjugate vaccine in non-human primates.

Weeratna RD, Chikh G, Zhang L, Fraser JD, Thorn JM, Merson JR, McCluskie MJ, Champion BR, Davis HL.

Immun Inflamm Dis. 2016 Apr 1;4(2):135-147. eCollection 2016 Jun.


Potential applications of nanoparticles in cancer immunotherapy.

Jia Y, Omri A, Krishnan L, McCluskie MJ.

Hum Vaccin Immunother. 2017 Jan 2;13(1):63-74. doi: 10.1080/21645515.2016.1245251. Epub 2016 Nov 21. Review.


The effect of preexisting anti-carrier immunity on subsequent responses to CRM197 or Qb-VLP conjugate vaccines.

McCluskie MJ, Evans DM, Zhang N, Benoit M, McElhiney SP, Unnithan M, DeMarco SC, Clay B, Huber C, Deora A, Thorn JM, Stead DR, Merson JR, Davis HL.

Immunopharmacol Immunotoxicol. 2016 Jun;38(3):184-96. doi: 10.3109/08923973.2016.1165246. Epub 2016 Apr 27.


Support for the revocation of general safety test regulations in biologics license applications.

Evans DM, Thorn JM, Arch-Douglas K, Sperry JB, Thompson B, Davis HL, McCluskie MJ.

Biologicals. 2016 May;44(3):178-81. doi: 10.1016/j.biologicals.2016.02.001. Epub 2016 Mar 17.


Anti-IgE Qb-VLP Conjugate Vaccine Self-Adjuvants through Activation of TLR7.

Akache B, Weeratna RD, Deora A, Thorn JM, Champion B, Merson JR, Davis HL, McCluskie MJ.

Vaccines (Basel). 2016 Jan 21;4(1). pii: E3. doi: 10.3390/vaccines4010003.


Anti-nicotine vaccines: Comparison of adjuvanted CRM197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates.

McCluskie MJ, Thorn J, Gervais DP, Stead DR, Zhang N, Benoit M, Cartier J, Kim IJ, Bhattacharya K, Finneman JI, Merson JR, Davis HL.

Int Immunopharmacol. 2015 Dec;29(2):663-671. doi: 10.1016/j.intimp.2015.09.012. Epub 2015 Sep 26.


Molecular attributes of conjugate antigen influence function of antibodies induced by anti-nicotine vaccine in mice and non-human primates.

McCluskie MJ, Thorn J, Mehelic PR, Kolhe P, Bhattacharya K, Finneman JI, Stead DR, Piatchek MB, Zhang N, Chikh G, Cartier J, Evans DM, Merson JR, Davis HL.

Int Immunopharmacol. 2015 Apr;25(2):518-27. doi: 10.1016/j.intimp.2015.02.030. Epub 2015 Feb 28.


Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice.

Pryde DC, Jones LH, Gervais DP, Stead DR, Blakemore DC, Selby MD, Brown AD, Coe JW, Badland M, Beal DM, Glen R, Wharton Y, Miller GJ, White P, Zhang N, Benoit M, Robertson K, Merson JR, Davis HL, McCluskie MJ.

PLoS One. 2013 Oct 1;8(10):e76557. doi: 10.1371/journal.pone.0076557. eCollection 2013.

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