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Items: 17


Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE.

Rathore SS, Liu Y, Yu H, Wan C, Lee M, Yin Q, Stowell MHB, Shen J.

Cell Rep. 2019 Dec 24;29(13):4583-4592.e3. doi: 10.1016/j.celrep.2019.11.107.


Flattening of Diluted Species Profile via Passive Geometry in a Microfluidic Device.

Miles M, Bhattacharjee B, Sridhar N, Fajrial AK, Ball K, Lee YC, Stowell MHB, Old WM, Ding X.

Micromachines (Basel). 2019 Nov 30;10(12). pii: E839. doi: 10.3390/mi10120839.


Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways.

Ruhl DA, Bomba-Warczak E, Watson ET, Bradberry MM, Peterson TA, Basu T, Frelka A, Evans CS, Briguglio JS, Basta T, Stowell MHB, Savas JN, Roopra A, Pearce RA, Piper RC, Chapman ER.

Nat Commun. 2019 Aug 6;10(1):3532. doi: 10.1038/s41467-019-11459-4.


Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating.

Maity K, Heumann JM, McGrath AP, Kopcho NJ, Hsu PK, Lee CW, Mapes JH, Garza D, Krishnan S, Morgan GP, Hendargo KJ, Klose T, Rees SD, Medrano-Soto A, Saier MH Jr, Piñeros M, Komives EA, Schroeder JI, Chang G, Stowell MHB.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14309-14318. doi: 10.1073/pnas.1900774116. Epub 2019 Jun 21.


Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies.

Janas T, Sapoń K, Stowell MHB, Janas T.

Int J Mol Sci. 2019 Jan 13;20(2). pii: E299. doi: 10.3390/ijms20020299.


Functional Reconstitution of Intracellular Vesicle Fusion Using Purified SNAREs and Sec1/Munc18 (SM) Proteins.

Yu H, Crisman L, Stowell MHB, Shen J.

Methods Mol Biol. 2019;1860:237-249. doi: 10.1007/978-1-4939-8760-3_15.


The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis.

Shen C, Liu Y, Yu H, Gulbranson DR, Kogut I, Bilousova G, Zhang C, Stowell MHB, Shen J.

J Biol Chem. 2018 Nov 23;293(47):18309-18317. doi: 10.1074/jbc.RA118.005254. Epub 2018 Oct 1.


SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins.

Yu H, Shen C, Liu Y, Menasche BL, Ouyang Y, Stowell MHB, Shen J.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8421-E8429. doi: 10.1073/pnas.1802645115. Epub 2018 Aug 20.


Identification of the primary peptide contaminant that inhibits fibrillation and toxicity in synthetic amyloid-β42.

Adams DJ, Nemkov TG, Mayer JP, Old WM, Stowell MHB.

PLoS One. 2017 Aug 9;12(8):e0182804. doi: 10.1371/journal.pone.0182804. eCollection 2017.


Exosomes and other extracellular vesicles in neural cells and neurodegenerative diseases.

Janas AM, Sapoń K, Janas T, Stowell MH, Janas T.

Biochim Biophys Acta. 2016 Jun;1858(6):1139-51. doi: 10.1016/j.bbamem.2016.02.011. Epub 2016 Feb 10. Review.


Self-assembled lipid and membrane protein polyhedral nanoparticles.

Basta T, Wu HJ, Morphew MK, Lee J, Ghosh N, Lai J, Heumann JM, Wang K, Lee YC, Rees DC, Stowell MH.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):670-4. doi: 10.1073/pnas.1321936111. Epub 2013 Dec 30.


Coordinating the impact of structural genomics on the human α-helical transmembrane proteome.

Pieper U, Schlessinger A, Kloppmann E, Chang GA, Chou JJ, Dumont ME, Fox BG, Fromme P, Hendrickson WA, Malkowski MG, Rees DC, Stokes DL, Stowell MH, Wiener MC, Rost B, Stroud RM, Stevens RC, Sali A.

Nat Struct Mol Biol. 2013 Feb;20(2):135-8. doi: 10.1038/nsmb.2508. No abstract available.


In vivo adsorption of autoantibodies in myasthenia gravis using Nanodisc-incorporated acetylcholine receptor.

Sheng JR, Grimme S, Bhattacharya P, Stowell MH, Artinger M, Prabahakar BS, Meriggioli MN.

Exp Neurol. 2010 Oct;225(2):320-7. doi: 10.1016/j.expneurol.2010.07.003. Epub 2010 Jul 15.


Structure of synaptophysin: a hexameric MARVEL-domain channel protein.

Arthur CP, Stowell MH.

Structure. 2007 Jun;15(6):707-14.


Electron tomographic methods for studying the chemical synapse.

Arthur CP, Serrell DB, Pagratis M, Potter DL, Finch DS, Stowell MH.

Methods Cell Biol. 2007;79:241-57. Review. No abstract available.


Rapid and simple protein-stability screens: application to membrane proteins.

Yeh AP, McMillan A, Stowell MH.

Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):451-7. Epub 2006 Mar 18.


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