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Items: 4

1.

Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor.

Meuser ME, Rashad AA, Ozorowski G, Dick A, Ward AB, Cocklin S.

Molecules. 2019 Apr 22;24(8). pii: E1581. doi: 10.3390/molecules24081581.

2.

Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action.

Xu JP, Francis AC, Meuser ME, Mankowski M, Ptak RG, Rashad AA, Melikyan GB, Cocklin S.

J Drug Des Res. 2018;5(2). pii: 1070. Epub 2018 Aug 13.

3.

Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library.

Wu G, Zalloum WA, Meuser ME, Jing L, Kang D, Chen CH, Tian Y, Zhang F, Cocklin S, Lee KH, Liu X, Zhan P.

Eur J Med Chem. 2018 Oct 5;158:478-492. doi: 10.1016/j.ejmech.2018.09.029. Epub 2018 Sep 11.

PMID:
30243152
4.

Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency.

Meuser ME, Murphy MB, Rashad AA, Cocklin S.

Molecules. 2018 Aug 3;23(8). pii: E1940. doi: 10.3390/molecules23081940.

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