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Items: 11


A minimal RNA ligand for potent RIG-I activation in living mice.

Linehan MM, Dickey TH, Molinari ES, Fitzgerald ME, Potapova O, Iwasaki A, Pyle AM.

Sci Adv. 2018 Feb 21;4(2):e1701854. doi: 10.1126/sciadv.1701854. eCollection 2018 Feb.


Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding.

Fitzgerald ME, Rawling DC, Potapova O, Ren X, Kohlway A, Pyle AM.

Nucleic Acids Res. 2017 Feb 17;45(3):1442-1454. doi: 10.1093/nar/gkw816.


Establishing the role of ATP for the function of the RIG-I innate immune sensor.

Rawling DC, Fitzgerald ME, Pyle AM.

Elife. 2015 Sep 15;4. pii: e09391. doi: 10.7554/eLife.09391.


Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells.

Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):827-32. doi: 10.1073/pnas.1411030112. Epub 2015 Jan 5.


An evolving arsenal: viral RNA detection by RIG-I-like receptors.

Fitzgerald ME, Rawling DC, Vela A, Pyle AM.

Curr Opin Microbiol. 2014 Aug;20:76-81. doi: 10.1016/j.mib.2014.05.004. Epub 2014 Jun 7. Review.


E2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex.

Coey CT, Fitzgerald ME, Maiti A, Reiter KH, Guzzo CM, Matunis MJ, Drohat AC.

J Biol Chem. 2014 May 30;289(22):15810-9. doi: 10.1074/jbc.M114.572081. Epub 2014 Apr 21.


Dicer-related helicase 3 forms an obligate dimer for recognizing 22G-RNA.

Fitzgerald ME, Vela A, Pyle AM.

Nucleic Acids Res. 2014 Apr;42(6):3919-30. doi: 10.1093/nar/gkt1383. Epub 2014 Jan 15.


Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA.

Morgan MT, Maiti A, Fitzgerald ME, Drohat AC.

Nucleic Acids Res. 2011 Mar;39(6):2319-29. doi: 10.1093/nar/gkq1164. Epub 2010 Nov 21.


Structural studies of RNA/DNA polypurine tracts.

Fitzgerald ME, Drohat AC.

Chem Biol. 2008 Mar;15(3):203-4. doi: 10.1016/j.chembiol.2008.03.001.


The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase.

Guan X, Madabushi A, Chang DY, Fitzgerald ME, Shi G, Drohat AC, Lu AL.

Nucleic Acids Res. 2007;35(18):6207-18. Epub 2007 Sep 12.

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