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Items: 1 to 20 of 24

1.

Dietary modulation of mitochondrial DNA damage: implications in aging and associated diseases.

Lam J, McKeague M.

J Nutr Biochem. 2018 Jul 7;63:1-10. doi: 10.1016/j.jnutbio.2018.07.003. [Epub ahead of print] Review.

PMID:
30071405
2.

The Base Pairing Partner Modulates Alkylguanine Alkyltransferase.

McKeague M, Otto C, Räz MH, Angelov T, Sturla SJ.

ACS Chem Biol. 2018 Sep 21;13(9):2534-2541. doi: 10.1021/acschembio.8b00446. Epub 2018 Aug 8.

PMID:
30040894
3.

Nucleotide-Resolution Genome-Wide Mapping of Oxidative DNA Damage by Click-Code-Seq.

Wu J, McKeague M, Sturla SJ.

J Am Chem Soc. 2018 Aug 8;140(31):9783-9787. doi: 10.1021/jacs.8b03715. Epub 2018 Jul 26.

PMID:
29944356
4.

PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.

Dörsam B, Seiwert N, Foersch S, Stroh S, Nagel G, Begaliew D, Diehl E, Kraus A, McKeague M, Minneker V, Roukos V, Reißig S, Waisman A, Moehler M, Stier A, Mangerich A, Dantzer F, Kaina B, Fahrer J.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4061-E4070. doi: 10.1073/pnas.1712345115. Epub 2018 Apr 9.

PMID:
29632181
5.

In Vitro Selection and Characterization of DNA Aptamers to a Small Molecule Target.

Ruscito A, McConnell EM, Koudrina A, Velu R, Mattice C, Hunt V, McKeague M, DeRosa MC.

Curr Protoc Chem Biol. 2017 Dec 14;9(4):233-268. doi: 10.1002/cpch.28.

PMID:
29241295
6.

Aptamers for DNA Damage and Repair.

McKeague M.

Int J Mol Sci. 2017 Oct 22;18(10). pii: E2212. doi: 10.3390/ijms18102212. Review.

7.

Functional nucleic acids as in vivo metabolite and ion biosensors.

Alsaafin A, McKeague M.

Biosens Bioelectron. 2017 Aug 15;94:94-106. doi: 10.1016/j.bios.2017.02.030. Epub 2017 Feb 21. Review.

PMID:
28262613
8.

Comparison of In-Solution Biorecognition Properties of Aptamers against Ochratoxin A.

McKeague M, Velu R, De Girolamo A, Valenzano S, Pascale M, Smith M, DeRosa MC.

Toxins (Basel). 2016 Nov 15;8(11). pii: E336.

9.

Design and Construction of Generalizable RNA-Protein Hybrid Controllers by Level-Matched Genetic Signal Amplification.

Wang YH, McKeague M, Hsu TM, Smolke CD.

Cell Syst. 2016 Dec 21;3(6):549-562.e7. doi: 10.1016/j.cels.2016.10.008. Epub 2016 Nov 10.

10.

Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines.

McKeague M, Wang YH, Cravens A, Win MN, Smolke CD.

Metab Eng. 2016 Nov;38:191-203. doi: 10.1016/j.ymben.2016.08.003. Epub 2016 Aug 9.

11.

Screening and Identification of DNA Aptamers to Tyramine Using in Vitro Selection and High-Throughput Sequencing.

Valenzano S, De Girolamo A, DeRosa MC, McKeague M, Schena R, Catucci L, Pascale M.

ACS Comb Sci. 2016 Jun 13;18(6):302-13. doi: 10.1021/acscombsci.5b00163. Epub 2016 Apr 26.

PMID:
27057927
12.

Opportunities in the design and application of RNA for gene expression control.

McKeague M, Wong RS, Smolke CD.

Nucleic Acids Res. 2016 Apr 20;44(7):2987-99. doi: 10.1093/nar/gkw151. Epub 2016 Mar 11. Review.

13.

Analysis of In Vitro Aptamer Selection Parameters.

McKeague M, McConnell EM, Cruz-Toledo J, Bernard ED, Pach A, Mastronardi E, Zhang X, Beking M, Francis T, Giamberardino A, Cabecinha A, Ruscito A, Aranda-Rodriguez R, Dumontier M, DeRosa MC.

J Mol Evol. 2015 Dec;81(5-6):150-61. doi: 10.1007/s00239-015-9708-6. Epub 2015 Nov 3. Review.

PMID:
26530075
14.

In Vitro Screening and in Silico Modeling of RNA-Based Gene Expression Control.

McKeague M, Wang YH, Smolke CD.

ACS Chem Biol. 2015 Nov 20;10(11):2463-2467. doi: 10.1021/acschembio.5b00518. Epub 2015 Sep 22.

15.

An in solution assay for interrogation of affinity and rational minimer design for small molecule-binding aptamers.

Frost NR, McKeague M, Falcioni D, DeRosa MC.

Analyst. 2015 Oct 7;140(19):6643-51. doi: 10.1039/c5an01075f. Epub 2015 Sep 3.

PMID:
26336657
16.

Comprehensive analytical comparison of strategies used for small molecule aptamer evaluation.

McKeague M, De Girolamo A, Valenzano S, Pascale M, Ruscito A, Velu R, Frost NR, Hill K, Smith M, McConnell EM, DeRosa MC.

Anal Chem. 2015 Sep 1;87(17):8608-12. doi: 10.1021/acs.analchem.5b02102. Epub 2015 Aug 15.

PMID:
26192270
17.

Facile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance.

Chang AL, McKeague M, Smolke CD.

Methods Enzymol. 2014;549:451-66. doi: 10.1016/B978-0-12-801122-5.00019-2.

18.

Selection and characterization of a novel DNA aptamer for label-free fluorescence biosensing of ochratoxin A.

McKeague M, Velu R, Hill K, Bardóczy V, Mészáros T, DeRosa MC.

Toxins (Basel). 2014 Aug 15;6(8):2435-52. doi: 10.3390/toxins6082435.

19.

Kinetic and equilibrium binding characterization of aptamers to small molecules using a label-free, sensitive, and scalable platform.

Chang AL, McKeague M, Liang JC, Smolke CD.

Anal Chem. 2014 Apr 1;86(7):3273-8. doi: 10.1021/ac5001527. Epub 2014 Mar 14.

20.

Challenges and opportunities for small molecule aptamer development.

McKeague M, Derosa MC.

J Nucleic Acids. 2012;2012:748913. doi: 10.1155/2012/748913. Epub 2012 Oct 24.

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