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Items: 1 to 20 of 211


Reducing bias in the analysis of solution-state NMR data with dynamics detectors.

Smith AA, Ernst M, Meier BH, Ferrage F.

J Chem Phys. 2019 Jul 21;151(3):034102. doi: 10.1063/1.5111081.


Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer.

Nguyen PM, Dagley LF, Preaudet A, Lam N, Giam M, Fung KY, Aizel K, van Duijneveldt G, Tan CW, Hirokawa Y, Yip HYK, Love CG, Poh AR, Cruz A, Burstroem C, Feltham R, Abdirahman SM, Meiselbach K, Low RRJ, Palmieri M, Ernst M, Webb AI, Burgess T, Sieber OM, Bouillet P, Putoczki TL.

Cell Death Differ. 2019 Jul 11. doi: 10.1038/s41418-019-0383-9. [Epub ahead of print]


The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo.

Flanagan D, Barker N, Ernst M, Vincan E, Phesse T.

Biomedicines. 2019 Jul 8;7(3). pii: E50. doi: 10.3390/biomedicines7030050.


IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.

Eissmann MF, Dijkstra C, Jarnicki A, Phesse T, Brunnberg J, Poh AR, Etemadi N, Tsantikos E, Thiem S, Huntington ND, Hibbs ML, Boussioutas A, Grimbaldeston MA, Buchert M, O'Donoghue RJJ, Masson F, Ernst M.

Nat Commun. 2019 Jun 21;10(1):2735. doi: 10.1038/s41467-019-10676-1.


Localized and Collective Motions in HET-s(218-289) Fibrils from Combined NMR Relaxation and MD Simulation.

Smith AA, Ernst M, Riniker S, Meier BH.

Angew Chem Int Ed Engl. 2019 Jul 8;58(28):9383-9388. doi: 10.1002/anie.201901929. Epub 2019 Jun 5.


A spin-thermodynamic approach to characterize spin dynamics in TEMPO-based samples for dissolution DNP at 7 T field.

Jähnig F, Himmler A, Kwiatkowski G, Däpp A, Hunkeler A, Kozerke S, Ernst M.

J Magn Reson. 2019 Jun;303:91-104. doi: 10.1016/j.jmr.2019.04.012. Epub 2019 Apr 25.


Measuring strong one-bond dipolar couplings using REDOR in magic-angle spinning solid-state NMR.

Jain MG, Mote KR, Hellwagner J, Rajalakshmi G, Ernst M, Madhu PK, Agarwal V.

J Chem Phys. 2019 Apr 7;150(13):134201. doi: 10.1063/1.5088100.


Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.

Thilakasiri P, Huynh J, Poh AR, Tan CW, Nero TL, Tran K, Parslow AC, Afshar-Sterle S, Baloyan D, Hannan NJ, Buchert M, Scott AM, Griffin MD, Hollande F, Parker MW, Putoczki TL, Ernst M, Chand AL.

EMBO Mol Med. 2019 Apr;11(4). pii: e9539. doi: 10.15252/emmm.201809539.


Spinning faster: protein NMR at MAS frequencies up to 126 kHz.

Penzel S, Oss A, Org ML, Samoson A, Böckmann A, Ernst M, Meier BH.

J Biomol NMR. 2019 Feb;73(1-2):19-29. doi: 10.1007/s10858-018-0219-9. Epub 2019 Jan 24.


Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.

Flanagan DJ, Barker N, Costanzo NSD, Mason EA, Gurney A, Meniel VS, Koushyar S, Austin CR, Ernst M, Pearson HB, Boussioutas A, Clevers H, Phesse TJ, Vincan E.

Cancer Res. 2019 Mar 1;79(5):970-981. doi: 10.1158/0008-5472.CAN-18-2095. Epub 2019 Jan 8.


Therapeutically exploiting STAT3 activity in cancer - using tissue repair as a road map.

Huynh J, Chand A, Gough D, Ernst M.

Nat Rev Cancer. 2019 Feb;19(2):82-96. doi: 10.1038/s41568-018-0090-8. Review.


Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective Rnpc3-deficient mice.

Doggett K, Williams BB, Markmiller S, Geng FS, Coates J, Mieruszynski S, Ernst M, Thomas T, Heath JK.

RNA. 2018 Dec;24(12):1856-1870. doi: 10.1261/rna.068221.118. Epub 2018 Sep 25.


Direct amide 15N to 13C transfers for solid-state assignment experiments in deuterated proteins.

Lends A, Ravotti F, Zandomeneghi G, Böckmann A, Ernst M, Meier BH.

J Biomol NMR. 2018 Oct;72(1-2):69-78. doi: 10.1007/s10858-018-0207-0. Epub 2018 Sep 11.


Setting the magic angle for fast magic-angle spinning probes.

Penzel S, Smith AA, Ernst M, Meier BH.

J Magn Reson. 2018 Aug;293:115-122. doi: 10.1016/j.jmr.2018.06.002. Epub 2018 Jun 15.


Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Ziegler PK, Bollrath J, Pallangyo CK, Matsutani T, Canli Ö, De Oliveira T, Diamanti MA, Müller N, Gamrekelashvili J, Putoczki T, Horst D, Mankan AK, Öner MG, Müller S, Müller-Höcker J, Kirchner T, Slotta-Huspenina J, Taketo MM, Reinheckel T, Dröse S, Larner AC, Wels WS, Ernst M, Greten TF, Arkan MC, Korn T, Wirth D, Greten FR.

Cell. 2018 Jun 28;174(1):88-101.e16. doi: 10.1016/j.cell.2018.05.028. Epub 2018 Jun 14.


MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.

Sakthianandeswaren A, Parsons MJ, Mouradov D, MacKinnon RN, Catimel B, Liu S, Palmieri M, Love C, Jorissen RN, Li S, Whitehead L, Putoczki TL, Preaudet A, Tsui C, Nowell CJ, Ward RL, Hawkins NJ, Desai J, Gibbs P, Ernst M, Street I, Buchert M, Sieber OM.

Cancer Discov. 2018 Aug;8(8):988-1005. doi: 10.1158/2159-8290.CD-17-0909. Epub 2018 Jun 7.


Author Correction: Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms.

Kim DS, Dastidar H, Zhang C, Zemp FJ, Lau K, Ernst M, Rakic A, Sikdar S, Rajwani J, Naumenko V, Balce DR, Ewanchuk BW, Tailor P, Yates RM, Jenne C, Gafuik C, Mahoney DJ.

Nat Commun. 2018 May 24;9(1):2109. doi: 10.1038/s41467-018-04597-8.


Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer.

Johnstone CN, Pattison AD, Gorringe KL, Harrison PF, Powell DR, Lock P, Baloyan D, Ernst M, Stewart AG, Beilharz TH, Anderson RL.

Dis Model Mech. 2018 May 29;11(5). pii: dmm032250. doi: 10.1242/dmm.032250.


Machine Learning of Biomolecular Reaction Coordinates.

Brandt S, Sittel F, Ernst M, Stock G.

J Phys Chem Lett. 2018 May 3;9(9):2144-2150. doi: 10.1021/acs.jpclett.8b00759. Epub 2018 Apr 12.


Targeting Macrophages in Cancer: From Bench to Bedside.

Poh AR, Ernst M.

Front Oncol. 2018 Mar 12;8:49. doi: 10.3389/fonc.2018.00049. eCollection 2018. Review.

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