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Items: 14

1.

Occurrence of Selected Organic Contaminants in Edible Insects and Assessment of Their Chemical Safety.

Poma G, Yin S, Tang B, Fujii Y, Cuykx M, Covaci A.

Environ Health Perspect. 2019 Dec;127(12):127009. doi: 10.1289/EHP5782. Epub 2019 Dec 31.

2.

Exposure of HepaRG Cells to Sodium Saccharin Underpins the Importance of Including Non-Hepatotoxic Compounds When Investigating Toxicological Modes of Action Using Metabolomics.

Cuykx M, Beirnaert C, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A.

Metabolites. 2019 Nov 4;9(11). pii: E265. doi: 10.3390/metabo9110265.

3.

Untargeted liquid chromatography-mass spectrometry metabolomics to assess drug-induced cholestatic features in HepaRG® cells.

Cuykx M, Beirnaert C, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A.

Toxicol Appl Pharmacol. 2019 Sep 15;379:114666. doi: 10.1016/j.taap.2019.114666. Epub 2019 Jul 16.

PMID:
31323262
4.

Using Expert Driven Machine Learning to Enhance Dynamic Metabolomics Data Analysis.

Beirnaert C, Peeters L, Meysman P, Bittremieux W, Foubert K, Custers D, Van der Auwera A, Cuykx M, Pieters L, Covaci A, Laukens K.

Metabolites. 2019 Mar 20;9(3). pii: E54. doi: 10.3390/metabo9030054.

5.

Targeted and non-target screening of persistent organic pollutants and organophosphorus flame retardants in leachate and sediment from landfill sites in Gauteng Province, South Africa.

Sibiya I, Poma G, Cuykx M, Covaci A, Daso Adegbenro P, Okonkwo J.

Sci Total Environ. 2019 Feb 25;653:1231-1239. doi: 10.1016/j.scitotenv.2018.10.356. Epub 2018 Oct 28.

PMID:
30759563
6.

Mass spectrometric identification of in vitro-generated metabolites of two emerging organophosphate flame retardants: V6 and BDP.

Alves A, Erratico C, Lucattini L, Cuykx M, Ballesteros-Gómez A, Leonards PEG, Voorspoels S, Covaci A.

Chemosphere. 2018 Dec;212:1047-1057. doi: 10.1016/j.chemosphere.2018.08.142. Epub 2018 Sep 3.

PMID:
30286534
7.

Occurrence of organophosphorus flame retardants and plasticizers in wild insects from a former e-waste recycling site in the Guangdong province, South China.

Poma G, Liu Y, Cuykx M, Tang B, Luo XJ, Covaci A.

Sci Total Environ. 2019 Feb 10;650(Pt 1):709-712. doi: 10.1016/j.scitotenv.2018.09.067. Epub 2018 Sep 6.

PMID:
30212701
8.

In vitro assessment of hepatotoxicity by metabolomics: a review.

Cuykx M, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A.

Arch Toxicol. 2018 Oct;92(10):3007-3029. doi: 10.1007/s00204-018-2286-9. Epub 2018 Aug 25. Review.

PMID:
30155722
9.

In-vitro metabolomics to evaluate toxicity of particulate matter under environmentally realistic conditions.

Sánchez-Soberón F, Cuykx M, Serra N, Linares V, Bellés M, Covaci A, Schuhmacher M.

Chemosphere. 2018 Oct;209:137-146. doi: 10.1016/j.chemosphere.2018.06.065. Epub 2018 Jun 10.

PMID:
29929119
10.

In vitro Phase I and Phase II metabolism of the new designer benzodiazepine cloniprazepam using liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.

Mortelé O, Vervliet P, Gys C, Degreef M, Cuykx M, Maudens K, Covaci A, van Nuijs ALN, Lai FY.

J Pharm Biomed Anal. 2018 May 10;153:158-167. doi: 10.1016/j.jpba.2018.02.032. Epub 2018 Feb 21.

PMID:
29494888
11.

Metabolomics profiling of steatosis progression in HepaRG® cells using sodium valproate.

Cuykx M, Claes L, Rodrigues RM, Vanhaecke T, Covaci A.

Toxicol Lett. 2018 Apr;286:22-30. doi: 10.1016/j.toxlet.2017.12.015. Epub 2018 Jan 31.

PMID:
29355688
12.

Tailored liquid chromatography-mass spectrometry analysis improves the coverage of the intracellular metabolome of HepaRG cells.

Cuykx M, Negreira N, Beirnaert C, Van den Eede N, Rodrigues R, Vanhaecke T, Laukens K, Covaci A.

J Chromatogr A. 2017 Mar 3;1487:168-178. doi: 10.1016/j.chroma.2017.01.050. Epub 2017 Jan 23.

PMID:
28153450
13.

Evaluation of hazardous chemicals in edible insects and insect-based food intended for human consumption.

Poma G, Cuykx M, Amato E, Calaprice C, Focant JF, Covaci A.

Food Chem Toxicol. 2017 Feb;100:70-79. doi: 10.1016/j.fct.2016.12.006. Epub 2016 Dec 19.

PMID:
28007452
14.

Metabolomics analysis of the toxicity pathways of triphenyl phosphate in HepaRG cells and comparison to oxidative stress mechanisms caused by acetaminophen.

Van den Eede N, Cuykx M, Rodrigues RM, Laukens K, Neels H, Covaci A, Vanhaecke T.

Toxicol In Vitro. 2015 Dec;29(8):2045-54. doi: 10.1016/j.tiv.2015.08.012. Epub 2015 Aug 28.

PMID:
26318275

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