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P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients.

Kappler M, Kotrba J, Kaune T, Bache M, Rot S, Bethmann D, Wichmann H, Güttler A, Bilkenroth U, Horter S, Gallwitz L, Kessler J, Greither T, Taubert H, Eckert AW, Vordermark D.

Clin Transl Radiat Oncol. 2017 Jun 27;5:6-11. doi: 10.1016/j.ctro.2017.05.002. eCollection 2017 Aug.


Synthesis and biological investigation of new carbonic anhydrase IX (CAIX) inhibitors.

Vanchanagiri K, Emmerich D, Bruschke M, Bache M, Seifert F, Csuk R, Vordermark D, Paschke R.

Chem Biol Interact. 2018 Mar 25;284:12-23. doi: 10.1016/j.cbi.2018.02.014. Epub 2018 Feb 16.


CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients.

Greither T, Wedler A, Rot S, Keßler J, Kehlen A, Holzhausen HJ, Bache M, Würl P, Taubert H, Kappler M.

Int J Mol Sci. 2017 Dec 7;18(12). pii: E2648. doi: 10.3390/ijms18122648.


Automatic detection of DNA double strand breaks after irradiation using an γH2AX assay.

Hohmann T, Kessler J, Grabiec U, Bache M, Vordermark D, Dehghani F.

Histol Histopathol. 2018 May;33(5):475-485. doi: 10.14670/HH-11-945. Epub 2017 Nov 15.


Dynamics of Heat Shock Protein 70 Serum Levels As a Predictor of Clinical Response in Non-Small-Cell Lung Cancer and Correlation with the Hypoxia-Related Marker Osteopontin.

Ostheimer C, Gunther S, Bache M, Vordermark D, Multhoff G.

Front Immunol. 2017 Oct 18;8:1305. doi: 10.3389/fimmu.2017.01305. eCollection 2017.


The Impact of Non-Lethal Single-Dose Radiation on Tumor Invasion and Cytoskeletal Properties.

Hohmann T, Grabiec U, Vogel C, Ghadban C, Ensminger S, Bache M, Vordermark D, Dehghani F.

Int J Mol Sci. 2017 Sep 18;18(9). pii: E2001. doi: 10.3390/ijms18092001.


Salivary miR-93 and miR-200a as post-radiotherapy biomarkers in head and neck squamous cell carcinoma.

Greither T, Vorwerk F, Kappler M, Bache M, Taubert H, Kuhnt T, Hey J, Eckert AW.

Oncol Rep. 2017 Aug;38(2):1268-1275. doi: 10.3892/or.2017.5764. Epub 2017 Jun 28.


Inhibition of Carbonic Anhydrase IX by Ureidosulfonamide Inhibitor U104 Reduces Prostate Cancer Cell Growth, But Does Not Modulate Daunorubicin or Cisplatin Cytotoxicity.

Riemann A, Güttler A, Haupt V, Wichmann H, Reime S, Bache M, Vordermark D, Thews O.

Oncol Res. 2018 Mar 5;26(2):191-200. doi: 10.3727/096504017X14965111926391. Epub 2017 Jun 19.


miR-199a-5p regulates HIF-1α and OSGIN2 and its expression is correlated to soft-tissue sarcoma patients' outcome.

Keßler J, Rot S, Bache M, Kappler M, Würl P, Vordermark D, Taubert H, Greither T.

Oncol Lett. 2016 Dec;12(6):5281-5288. doi: 10.3892/ol.2016.5320. Epub 2016 Oct 26.


The relationship between tumor volume changes and serial plasma osteopontin detection during radical radiotherapy of non-small-cell lung cancer.

Ostheimer C, Schweyer F, Reese T, Bache M, Vordermark D.

Oncol Lett. 2016 Nov;12(5):3449-3456. Epub 2016 Sep 8.


Correction: Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy.

Gnanapragassam VS, Bork K, Galuska CE, Galuska SP, Glanz D, Nagasundaram M, Bache M, Vordermark D, Kohla G, Kannicht C, Schauer R, Horstkorte R.

PLoS One. 2016 Apr 19;11(4):e0154289. doi: 10.1371/journal.pone.0154289. eCollection 2016. No abstract available.


Normoxic accumulation of HIF1α is associated with glutaminolysis.

Kappler M, Pabst U, Rot S, Taubert H, Wichmann H, Schubert J, Bache M, Weinholdt C, Immel UD, Grosse I, Vordermark D, Eckert AW.

Clin Oral Investig. 2017 Jan;21(1):211-224. doi: 10.1007/s00784-016-1780-9. Epub 2016 Mar 9.


Betulinyl Sulfamates as Anticancer Agents and Radiosensitizers in Human Breast Cancer Cells.

Bache M, Münch C, Güttler A, Wichmann H, Theuerkorn K, Emmerich D, Paschke R, Vordermark D.

Int J Mol Sci. 2015 Nov 3;16(11):26249-62. doi: 10.3390/ijms161125953.


IDH1(R132H) mutation causes a less aggressive phenotype and radiosensitizes human malignant glioma cells independent of the oxygenation status.

Kessler J, Güttler A, Wichmann H, Rot S, Kappler M, Bache M, Vordermark D.

Radiother Oncol. 2015 Sep;116(3):381-7. doi: 10.1016/j.radonc.2015.08.007. Epub 2015 Aug 29.


mRNA expression levels of hypoxia-induced and stem cell-associated genes in human glioblastoma.

Bache M, Rot S, Keßler J, Güttler A, Wichmann H, Greither T, Wach S, Taubert H, Söling A, Bilkenroth U, Kappler M, Vordermark D.

Oncol Rep. 2015 Jun;33(6):3155-61. doi: 10.3892/or.2015.3932. Epub 2015 Apr 27.


Prognostic information of serial plasma osteopontin measurement in radiotherapy of non-small-cell lung cancer.

Ostheimer C, Bache M, Güttler A, Reese T, Vordermark D.

BMC Cancer. 2014 Nov 21;14:858. doi: 10.1186/1471-2407-14-858.


Betulinic acid derivatives NVX-207 and B10 for treatment of glioblastoma--an in vitro study of cytotoxicity and radiosensitization.

Bache M, Bernhardt S, Passin S, Wichmann H, Hein A, Zschornak M, Kappler M, Taubert H, Paschke R, Vordermark D.

Int J Mol Sci. 2014 Oct 30;15(11):19777-90. doi: 10.3390/ijms151119777.


Targeting of EGFR and HER2 with therapeutic antibodies and siRNA: a comparative study in glioblastoma cells.

Wichmann H, Güttler A, Bache M, Taubert H, Rot S, Kessler J, Eckert AW, Kappler M, Vordermark D.

Strahlenther Onkol. 2015 Feb;191(2):180-91. doi: 10.1007/s00066-014-0743-9. Epub 2014 Aug 27.


Sialic acid metabolic engineering: a potential strategy for the neuroblastoma therapy.

Gnanapragassam VS, Bork K, Galuska CE, Galuska SP, Glanz D, Nagasundaram M, Bache M, Vordermark D, Kohla G, Kannicht C, Schauer R, Horstkorte R.

PLoS One. 2014 Aug 22;9(8):e105403. doi: 10.1371/journal.pone.0105403. eCollection 2014. Erratum in: PLoS One. 2016;11(4):e0154289.


Inverse prognostic impact of ErbB2 mRNA and protein expression level in tumors of soft tissue sarcoma patients.

Wichmann H, Güttler A, Bache M, Taubert H, Vetter M, Würl P, Holzhausen HJ, Eckert AW, Kappler M, Vordermark D.

Strahlenther Onkol. 2014 Oct;190(10):912-8. doi: 10.1007/s00066-014-0655-8. Epub 2014 Apr 9.


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