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Items: 15


Polyphenol Microbial Metabolites Exhibit Gut and Blood⁻Brain Barrier Permeability and Protect Murine Microglia against LPS-Induced Inflammation.

Johnson SL, Kirk RD, DaSilva NA, Ma H, Seeram NP, Bertin MJ.

Metabolites. 2019 Apr 19;9(4). pii: E78. doi: 10.3390/metabo9040078.


Cyanobufalins: Cardioactive Toxins from Cyanobacterial Blooms.

He H, Bertin MJ, Wu S, Wahome PG, Beauchesne KR, Youngs RO, Zimba PV, Moeller PDR, Sauri J, Carter GT.

J Nat Prod. 2018 Nov 26;81(11):2576-2581. doi: 10.1021/acs.jnatprod.8b00736. Epub 2018 Oct 28.


Trichophycins B-F, Chlorovinylidene-Containing Polyketides Isolated from a Cyanobacterial Bloom.

Bertin MJ, Saurí J, Liu Y, Via CW, Roduit AF, Williamson RT.

J Org Chem. 2018 Nov 2;83(21):13256-13266. doi: 10.1021/acs.joc.8b02070. Epub 2018 Oct 17.


The Metabolome of a Cyanobacterial Bloom Visualized by MS/MS-Based Molecular Networking Reveals New Neurotoxic Smenamide Analogs (C, D, and E).

Via CW, Glukhov E, Costa S, Zimba PV, Moeller PDR, Gerwick WH, Bertin MJ.

Front Chem. 2018 Jul 26;6:316. doi: 10.3389/fchem.2018.00316. eCollection 2018.


Microcystins Containing Doubly Homologated Tyrosine Residues from a Microcystis aeruginosa Bloom: Structures and Cytotoxicity.

He H, Wu S, Wahome PG, Bertin MJ, Pedone AC, Beauchesne KR, Moeller PDR, Carter GT.

J Nat Prod. 2018 Jun 22;81(6):1368-1375. doi: 10.1021/acs.jnatprod.7b00986. Epub 2018 May 30.


Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high.

Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6273. doi: 10.1073/pnas.1711139114. Epub 2017 Jul 14. No abstract available.


Tricholides A and B and Unnarmicin D: New Hybrid PKS-NRPS Macrocycles Isolated from an Environmental Collection of Trichodesmium thiebautii.

Bertin MJ, Roduit AF, Sun J, Alves GE, Via CW, Gonzalez MA, Zimba PV, Moeller PDR.

Mar Drugs. 2017 Jun 30;15(7). pii: E206. doi: 10.3390/md15070206.


Retrospective analysis of natural products provides insights for future discovery trends.

Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):5601-5606. doi: 10.1073/pnas.1614680114. Epub 2017 May 1.


Trichophycin A, a Cytotoxic Linear Polyketide Isolated from a Trichodesmium thiebautii Bloom.

Bertin MJ, Wahome PG, Zimba PV, He H, Moeller PD.

Mar Drugs. 2017 Jan 6;15(1). pii: E10. doi: 10.3390/md15010010.


The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide.

Bertin MJ, Vulpanovici A, Monroe EA, Korobeynikov A, Sherman DH, Gerwick L, Gerwick WH.

Chembiochem. 2016 Jan;17(2):164-73. doi: 10.1002/cbic.201500467. Epub 2015 Dec 23.


Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities.

Bertin MJ, Demirkiran O, Navarro G, Moss NA, Lee J, Goldgof GM, Vigil E, Winzeler EA, Valeriote FA, Gerwick WH.

Phytochemistry. 2016 Feb;122:113-118. doi: 10.1016/j.phytochem.2015.11.011. Epub 2015 Nov 26.


Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery.

Moss NA, Bertin MJ, Kleigrewe K, Leão TF, Gerwick L, Gerwick WH.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):313-24. doi: 10.1007/s10295-015-1705-7. Epub 2015 Nov 17. Review.


Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta.

Bertin MJ, Schwartz SL, Lee J, Korobeynikov A, Dorrestein PC, Gerwick L, Gerwick WH.

J Nat Prod. 2015 Mar 27;78(3):493-9. doi: 10.1021/np5009762. Epub 2015 Feb 10.


The effect of pH on the toxicity of fatty acids and fatty acid amides to rainbow trout gill cells.

Bertin MJ, Voronca DC, Chapman RW, Moeller PD.

Aquat Toxicol. 2014 Jan;146:1-11. doi: 10.1016/j.aquatox.2013.09.026. Epub 2013 Oct 23.


Using machine learning tools to model complex toxic interactions with limited sampling regimes.

Bertin MJ, Moeller P, Guillette LJ Jr, Chapman RW.

Environ Sci Technol. 2013 Mar 19;47(6):2728-36. doi: 10.1021/es3033549. Epub 2013 Feb 22.


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