Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 124


Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer.

Mitran B, Varasteh Z, Abouzayed A, Rinne SS, Puuvuori E, De Rosa M, Larhed M, Tolmachev V, Orlova A, Rosenström U.

Cancers (Basel). 2019 Sep 14;11(9). pii: E1371. doi: 10.3390/cancers11091371.


Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer.

Abouzayed A, Yim CB, Mitran B, Rinne SS, Tolmachev V, Larhed M, Rosenström U, Orlova A.

Pharmaceutics. 2019 Jul 23;11(7). pii: E358. doi: 10.3390/pharmaceutics11070358.


Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass.

Eriksson J, Roy T, Sawadjoon S, Bachmann K, Sköld C, Larhed M, Weis J, Selvaraju RK, Korsgren O, Eriksson O, Odell LR.

Nucl Med Biol. 2019 Apr;71:1-10. doi: 10.1016/j.nucmedbio.2019.04.002. Epub 2019 Apr 13.


Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177 Lu-DOTAGA-PEG2 -RM26.

Mitran B, Rinne SS, Konijnenberg MW, Maina T, Nock BA, Altai M, Vorobyeva A, Larhed M, Tolmachev V, de Jong M, Rosenström U, Orlova A.

Int J Cancer. 2019 Dec 15;145(12):3347-3358. doi: 10.1002/ijc.32401. Epub 2019 May 23.


A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode.

Isaksson R, Lindman J, Wannberg J, Sallander J, Backlund M, Baraldi D, Widdop R, Hallberg M, Åqvist J, Gutierrez de Teran H, Gising J, Larhed M.

ChemistryOpen. 2019 Jan 24;8(1):114-125. doi: 10.1002/open.201800282. eCollection 2019 Jan.


Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides.

Vanga SR, Sävmarker J, Ng L, Larhed M, Hallberg M, Åqvist J, Hallberg A, Chai SY, Gutiérrez-de-Terán H.

ACS Omega. 2018 Apr 30;3(4):4509-4521. doi: 10.1021/acsomega.8b00595. Epub 2018 Apr 25.


A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes.

Wannberg J, Isaksson R, Bremberg U, Backlund M, Sävmarker J, Hallberg M, Larhed M.

Bioorg Med Chem Lett. 2018 Feb 1;28(3):519-522. doi: 10.1016/j.bmcl.2017.11.042. Epub 2017 Nov 24.


High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26.

Mitran B, Thisgaard H, Rosenström U, Dam JH, Larhed M, Tolmachev V, Orlova A.

Contrast Media Mol Imaging. 2017 Aug 10;2017:6873684. doi: 10.1155/2017/6873684. eCollection 2017.


Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide.

Åkerbladh L, Chow SY, Odell LR, Larhed M.

ChemistryOpen. 2017 Aug 16;6(5):620-628. doi: 10.1002/open.201700130. eCollection 2017 Oct.


Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide.

Åkerbladh L, Chow SY, Odell LR, Larhed M.

ChemistryOpen. 2017 Sep 7;6(5):609. doi: 10.1002/open.201700145. eCollection 2017 Oct.


Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines.

Åkerbladh L, Schembri LS, Larhed M, Odell LR.

J Org Chem. 2017 Dec 1;82(23):12520-12529. doi: 10.1021/acs.joc.7b02294. Epub 2017 Oct 27.


Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.

Roslin S, Brandt P, Nordeman P, Larhed M, Odell LR, Eriksson J.

Molecules. 2017 Oct 10;22(10). pii: E1688. doi: 10.3390/molecules22101688.


Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation.

Rydfjord J, Skillinghaug B, Brandt P, Odell LR, Larhed M.

Org Lett. 2017 Aug 4;19(15):4066-4069. doi: 10.1021/acs.orglett.7b01836. Epub 2017 Jul 25.


Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction.

Roy T, Brandt P, Wetzel A, Bergman J, Brånalt J, Sävmarker J, Larhed M.

Org Lett. 2017 May 19;19(10):2738-2741. doi: 10.1021/acs.orglett.7b01094. Epub 2017 May 4.


Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki-Heck Reactions.

Wetzel A, Bergman J, Brandt P, Larhed M, Brånalt J.

Org Lett. 2017 Apr 7;19(7):1602-1605. doi: 10.1021/acs.orglett.7b00325. Epub 2017 Mar 14.


Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter.

Roslin S, De Rosa M, Deuther-Conrad W, Eriksson J, Odell LR, Antoni G, Brust P, Larhed M.

Bioorg Med Chem. 2017 Oct 1;25(19):5095-5106. doi: 10.1016/j.bmc.2017.01.041. Epub 2017 Jan 25.


Synthesis of 11C-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [11C]CO.

Stevens MY, Chow SY, Estrada S, Eriksson J, Asplund V, Orlova A, Mitran B, Antoni G, Larhed M, Åberg O, Odell LR.

ChemistryOpen. 2016 Oct 5;5(6):566-573. doi: 10.1002/open.201600091. eCollection 2016 Dec.


Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures.

Diwakarla S, Nylander E, Grönbladh A, Vanga SR, Khan YS, Gutiérrez-de-Terán H, Sävmarker J, Ng L, Pham V, Lundbäck T, Jenmalm-Jensen A, Svensson R, Artursson P, Zelleroth S, Engen K, Rosenström U, Larhed M, Åqvist J, Chai SY, Hallberg M.

ACS Chem Neurosci. 2016 Oct 19;7(10):1383-1392. Epub 2016 Aug 8.


Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening.

Engen K, Rosenström U, Axelsson H, Konda V, Dahllund L, Otrocka M, Sigmundsson K, Nikolaou A, Vauquelin G, Hallberg M, Jenmalm Jensen A, Lundbäck T, Larhed M.

Assay Drug Dev Technol. 2016 Apr;14(3):180-93. doi: 10.1089/adt.2016.708.


Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

Mitran B, Varasteh Z, Selvaraju RK, Lindeberg G, Sörensen J, Larhed M, Tolmachev V, Rosenström U, Orlova A.

Int J Oncol. 2016 May;48(5):2124-34. doi: 10.3892/ijo.2016.3429. Epub 2016 Mar 9.


Supplemental Content

Loading ...
Support Center