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Efficacy and Safety of Tailored and Dose-Dense Adjuvant Chemotherapy and Trastuzumab for Resected HER2-Positive Breast Cancer: Results From the Phase 3 PANTHER Trial.

Papakonstantinou A, Matikas A, Bengtsson NO, Malmström P, Hedayati E, Steger G, Untch M, Hübbert L, Johansson H, Hellström M, Gnant M, Loibl S, Greil R, Moebus V, Foukakis T, Bergh J.

Cancer. 2019 Dec 18. doi: 10.1002/cncr.32653. [Epub ahead of print]


The Impact of Age and Luminal Preservation on the Development of Intestinal Preservation Injury in Rats.

Søfteland JM, Casselbrant A, Akyürek LM, Hellström M, Oltean M.

Transplantation. 2020 Jan;104(1):e8-e15. doi: 10.1097/TP.0000000000002999.


Vinflunine/gemcitabine versus carboplatin/gemcitabine as first-line treatment in cisplatin-ineligible patients with advanced urothelial carcinoma: A randomised phase II trial (VINGEM).

Holmsten K, Jensen NV, Mouritsen LS, Jonsson E, Mellnert C, Agerbæk M, Nilsson C, Moe M, Carus A, Öfverholm E, Lahdenperä O, Brandberg Y, Johansson H, Hellström M, Maase HV, Pappot H, Ullén A.

Eur J Cancer. 2019 Oct 21. pii: S0959-8049(19)30726-9. doi: 10.1016/j.ejca.2019.08.033. [Epub ahead of print]


Neutropenic complications in the PANTHER phase III study of adjuvant tailored dose-dense chemotherapy in early breast cancer.

Papakonstantinou A, Hedayati E, Hellström M, Johansson H, Gnant M, Steger G, Greil R, Untch M, Moebus V, Loibl S, Foukakis T, Bergh J, Matikas A.

Acta Oncol. 2020 Jan;59(1):75-81. doi: 10.1080/0284186X.2019.1670353. Epub 2019 Oct 4.


Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2.

Testini C, Smith RO, Jin Y, Martinsson P, Sun Y, Hedlund M, Sáinz-Jaspeado M, Shibuya M, Hellström M, Claesson-Welsh L.

EMBO Rep. 2019 Nov 5;20(11):e47845. doi: 10.15252/embr.201947845. Epub 2019 Sep 23.


Intestinal Preservation Injury: A Comparison Between Rat, Porcine and Human Intestines.

Søfteland JM, Casselbrant A, Biglarnia AR, Linders J, Hellström M, Pesce A, Padma AM, Jiga LP, Hoinoiu B, Ionac M, Oltean M.

Int J Mol Sci. 2019 Jun 27;20(13). pii: E3135. doi: 10.3390/ijms20133135.


Decellularization of the mouse ovary: comparison of different scaffold generation protocols for future ovarian bioengineering.

Alshaikh AB, Padma AM, Dehlin M, Akouri R, Song MJ, Brännström M, Hellström M.

J Ovarian Res. 2019 Jun 22;12(1):58. doi: 10.1186/s13048-019-0531-3.


The development of an extended normothermic ex vivo reperfusion model of the sheep uterus to evaluate organ quality after cold ischemia in relation to uterus transplantation.

Padma AM, Truong M, Jar-Allah T, Song MJ, Oltean M, Brännström M, Hellström M.

Acta Obstet Gynecol Scand. 2019 Sep;98(9):1127-1138. doi: 10.1111/aogs.13617. Epub 2019 Apr 23.


Systematic in vitro comparison of decellularization protocols for blood vessels.

Simsa R, Padma AM, Heher P, Hellström M, Teuschl A, Jenndahl L, Bergh N, Fogelstrand P.

PLoS One. 2018 Dec 17;13(12):e0209269. doi: 10.1371/journal.pone.0209269. eCollection 2018.


Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Gene Editing Technique in Xenotransplantation.

Naeimi Kararoudi M, Hejazi SS, Elmas E, Hellström M, Naeimi Kararoudi M, Padma AM, Lee D, Dolatshad H.

Front Immunol. 2018 Sep 5;9:1711. doi: 10.3389/fimmu.2018.01711. eCollection 2018. Review.


Pharmacogenetic impact of docetaxel on neoadjuvant treatment of breast cancer patients.

Sim S, Bergh J, Hellström M, Hatschek T, Xie H.

Pharmacogenomics. 2018 Nov;19(16):1259-1268. doi: 10.2217/pgs-2018-0080. Epub 2018 Sep 10.


Luminal Polyethylene Glycol Alleviates Intestinal Preservation Injury Irrespective of Molecular Size.

Casselbrant A, Söfteland JM, Hellström M, Malinauskas M, Oltean M.

J Pharmacol Exp Ther. 2018 Jul;366(1):29-36. doi: 10.1124/jpet.117.247023. Epub 2018 May 8.


Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.

Kundu S, Ali MA, Handin N, Padhan N, Larsson J, Karoutsou M, Ban K, Wiśniewski JR, Artursson P, He L, Hellström M, Sjöblom T.

Genome Med. 2018 Jan 4;10(1):2. doi: 10.1186/s13073-017-0511-4.


Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth.

Pandzic T, Rendo V, Lim J, Larsson C, Larsson J, Stoimenov I, Kundu S, Ali MA, Hellström M, He L, Lindroth AM, Sjöblom T.

Oncotarget. 2017 Oct 9;8(58):98646-98659. doi: 10.18632/oncotarget.21713. eCollection 2017 Nov 17.


Long-term safety and survival outcomes from the Scandinavian Breast Group 2004-1 randomized phase II trial of tailored dose-dense adjuvant chemotherapy for early breast cancer.

Matikas A, Margolin S, Hellström M, Johansson H, Bengtsson NO, Karlsson L, Edlund P, Karlsson P, Lidbrink E, Linderholm B, Lindman H, Malmstrom P, Villman K, Foukakis T, Bergh J.

Breast Cancer Res Treat. 2018 Apr;168(2):349-355. doi: 10.1007/s10549-017-4599-4. Epub 2017 Nov 30.


Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.

Egaña I, Kaito H, Nitzsche A, Becker L, Ballester-Lopez C, Niaudet C, Petkova M, Liu W, Vanlandewijck M, Vernaleken A, Klopstock T, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Rask-Andersen H, Johansson HJ, Lehtiö J, He L, Yildirim AÖ, Hellström M; German Mouse Clinic Consortium.

Sci Rep. 2017 Nov 13;7(1):15453. doi: 10.1038/s41598-017-14894-9.


Assessment of early response biomarkers in relation to long-term survival in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy plus bevacizumab: Results from the Phase II PROMIX trial.

Kimbung S, Markholm I, Bjöhle J, Lekberg T, von Wachenfeldt A, Azavedo E, Saracco A, Hellström M, Veerla S, Paquet E, Bendahl PO, Fernö M, Bergh J, Loman N, Hatschek T, Hedenfalk I; PROMIX Trialists Group.

Int J Cancer. 2018 Feb 1;142(3):618-628. doi: 10.1002/ijc.31070. Epub 2017 Oct 13.


A sequential assessment of the preservation injury in porcine intestines.

Oltean M, Jiga L, Hellström M, Söfteland J, Papurica M, Hoinoiu T, Ionac M, Casselbrant A.

J Surg Res. 2017 Aug;216:149-157. doi: 10.1016/j.jss.2017.05.002. Epub 2017 May 8.


Protocols for Rat Uterus Isolation and Decellularization: Applications for Uterus Tissue Engineering and 3D Cell Culturing.

Padma AM, Tiemann TT, Alshaikh AB, Akouri R, Song MJ, Hellström M.

Methods Mol Biol. 2018;1577:161-175. doi: 10.1007/7651_2017_60.


Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model.

Park JH, Choi JY, Son DJ, Park EK, Song MJ, Hellström M, Hong JT.

Int J Mol Sci. 2017 Mar 30;18(4). pii: E738. doi: 10.3390/ijms18040738.

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