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Items: 3

1.

Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα.

Bergant K, Janežič M, Valjavec K, Sosič I, Pajk S, Štampar M, Žegura B, Gobec S, Filipič M, Perdih A.

Eur J Med Chem. 2019 Aug 1;175:330-348. doi: 10.1016/j.ejmech.2019.04.055. Epub 2019 Apr 25.

PMID:
31096154
2.

Bioassays and In Silico Methods in the Identification of Human DNA Topoisomerase IIα Inhibitors.

Bergant K, Janezic M, Perdih A.

Curr Med Chem. 2018;25(28):3286-3318. doi: 10.2174/0929867325666180306165725. Review.

PMID:
29508675
3.

4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site.

Pogorelčnik B, Janežič M, Sosič I, Gobec S, Solmajer T, Perdih A.

Bioorg Med Chem. 2015 Aug 1;23(15):4218-29. doi: 10.1016/j.bmc.2015.06.049. Epub 2015 Jul 2.

PMID:
26183545

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