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Items: 1 to 20 of 214

1.

Perfusion cell culture for the production of conjugated recombinant fusion proteins reduces clipping and quality heterogeneity compared to batch-mode processes.

Bielser JM, Chappuis L, Xiao Y, Souquet J, Broly H, Morbidelli M.

J Biotechnol. 2019 Jun 14. pii: S0168-1656(19)30485-7. doi: 10.1016/j.jbiotec.2019.06.006. [Epub ahead of print]

PMID:
31207262
2.

Process for continuous Fab production by digestion of IgG.

Ulmer N, Ristanovic D, Morbidelli M.

Biotechnol J. 2019 Jun 6:e1800677. doi: 10.1002/biot.201800677. [Epub ahead of print]

PMID:
31169346
3.

A new flow cell and chemometric protocol for implementing in-line Raman spectroscopy in chromatography.

Feidl F, Garbellini S, Vogg S, Sokolov M, Souquet J, Broly H, Butté A, Morbidelli M.

Biotechnol Prog. 2019 May 17:e2847. doi: 10.1002/btpr.2847. [Epub ahead of print]

PMID:
31099991
4.

Macroporous Polymer⁻Protein Hybrid Materials for Antibody Purification by Combination of Reactive Gelation and Click-Chemistry.

Lorenz M, Paganini C, Storti G, Morbidelli M.

Materials (Basel). 2019 May 14;12(10). pii: E1580. doi: 10.3390/ma12101580.

5.

Process design and development of a mammalian cell perfusion culture in shake-tube and benchtop bioreactors.

Wolf MKF, Müller A, Souquet J, Broly H, Morbidelli M.

Biotechnol Bioeng. 2019 Apr 30. doi: 10.1002/bit.26999. [Epub ahead of print]

PMID:
31038199
6.

Transcriptome and proteome analysis of steady-state in a perfusion CHO cell culture process.

Bertrand V, Karst DJ, Bachmann A, Cantalupo K, Soos M, Morbidelli M.

Biotechnol Bioeng. 2019 Apr 18. doi: 10.1002/bit.26996. [Epub ahead of print]

PMID:
30997936
7.

Decision Tree-PLS (DT-PLS) algorithm for the development of process: Specific local prediction models.

Narayanan H, Sokolov M, Butté A, Morbidelli M.

Biotechnol Prog. 2019 Apr 10:e2818. doi: 10.1002/btpr.2818. [Epub ahead of print]

PMID:
30969466
8.

Core-Shell Morphology of Redispersible Powders in Polymer-Cement Waterproof Mortars.

Caimi S, Timmerer E, Banfi M, Storti G, Morbidelli M.

Polymers (Basel). 2018 Oct 10;10(10). pii: E1122. doi: 10.3390/polym10101122.

9.

Experimental Evaluation of the Impact of Intrinsic Process Parameters on the Performance of a Continuous Chromatographic Polishing Unit (MCSGP).

Vogg S, Ulmer N, Souquet J, Broly H, Morbidelli M.

Biotechnol J. 2019 Mar 30:e1800732. doi: 10.1002/biot.201800732. [Epub ahead of print]

PMID:
30927513
10.

Semi-continuous scale-down models for clone and operating parameter screening in perfusion bioreactors.

Bielser JM, Domaradzki J, Souquet J, Broly H, Morbidelli M.

Biotechnol Prog. 2019 May;35(3):e2790. doi: 10.1002/btpr.2790. Epub 2019 Mar 13.

PMID:
30773840
11.

Purification of Human Monoclonal Antibodies and Their Fragments.

Ulmer N, Vogg S, Müller-Späth T, Morbidelli M.

Methods Mol Biol. 2019;1904:163-188. doi: 10.1007/978-1-4939-8958-4_7.

PMID:
30539470
12.

Effect of SiO₂ Nanoparticles on the Performance of PVdF-HFP/Ionic Liquid Separator for Lithium-Ion Batteries.

Caimi S, Klaue A, Wu H, Morbidelli M.

Nanomaterials (Basel). 2018 Nov 8;8(11). pii: E926. doi: 10.3390/nano8110926.

13.

Model-assisted process characterization and validation for a continuous two-column protein A capture process.

Baur D, Angelo J, Chollangi S, Müller-Späth T, Xu X, Ghose S, Li ZJ, Morbidelli M.

Biotechnol Bioeng. 2019 Jan;116(1):87-98. doi: 10.1002/bit.26849. Epub 2018 Nov 6.

PMID:
30298905
14.

Continuous and Integrated Expression and Purification of Recombinant Antibodies.

Vogg S, Wolf MKF, Morbidelli M.

Methods Mol Biol. 2018;1850:147-178. doi: 10.1007/978-1-4939-8730-6_11.

PMID:
30242686
15.

Model assisted comparison of Protein A resins and multi-column chromatography for capture processes.

Baur D, Angelo JM, Chollangi S, Xu X, Müller-Späth T, Zhang N, Ghose S, Li ZJ, Morbidelli M.

J Biotechnol. 2018 Nov 10;285:64-73. doi: 10.1016/j.jbiotec.2018.08.014. Epub 2018 Aug 27.

PMID:
30165118
16.

Self-Assembling PCL-Based Nanoparticles as PTX Solubility Enhancer Excipients.

Capasso Palmiero U, Morosi L, Lupi M, Ponzo M, Frapolli R, Zucchetti M, Ubezio P, Morbidelli M, D'Incalci M, Bello E, Moscatelli D.

Macromol Biosci. 2018 Oct;18(10):e1800164. doi: 10.1002/mabi.201800164. Epub 2018 Jul 25.

PMID:
30047229
17.

Bottle-grade polyethylene furanoate from ring-opening polymerisation of cyclic oligomers.

Rosenboom JG, Hohl DK, Fleckenstein P, Storti G, Morbidelli M.

Nat Commun. 2018 Jul 24;9(1):2701. doi: 10.1038/s41467-018-05147-y.

18.

Development of a shake tube-based scale-down model for perfusion cultures.

Wolf MKF, Lorenz V, Karst DJ, Souquet J, Broly H, Morbidelli M.

Biotechnol Bioeng. 2018 Nov;115(11):2703-2713. doi: 10.1002/bit.26804. Epub 2018 Sep 10.

PMID:
30039852
19.

Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition.

Wolf MKF, Closet A, Bzowska M, Bielser JM, Souquet J, Broly H, Morbidelli M.

Biotechnol J. 2019 Feb;14(2):e1700722. doi: 10.1002/biot.201700722. Epub 2018 Jun 4.

PMID:
29781256
20.

Calixarene-immobilized monolithic cryogels for preparative protein chromatography.

Guven I, Gezici O, Bayrakci M, Morbidelli M.

J Chromatogr A. 2018 Jul 13;1558:59-68. doi: 10.1016/j.chroma.2018.05.026. Epub 2018 May 16.

PMID:
29778445

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