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Items: 1 to 20 of 22


Bouganin, an Attractive Weapon for Immunotoxins.

Bortolotti M, Bolognesi A, Polito L.

Toxins (Basel). 2018 Aug 8;10(8). pii: E323. doi: 10.3390/toxins10080323. Review.


The role of xanthine oxidoreductase and uric acid in metabolic syndrome.

Battelli MG, Bortolotti M, Polito L, Bolognesi A.

Biochim Biophys Acta. 2018 Aug;1864(8):2557-2565. doi: 10.1016/j.bbadis.2018.05.003. Epub 2018 May 5. Review.


Immunoconjugates for Osteosarcoma Therapy: Preclinical Experiences and Future Perspectives.

Mercatelli D, Bortolotti M, Bazzocchi A, Bolognesi A, Polito L.

Biomedicines. 2018 Feb 10;6(1). pii: E19. doi: 10.3390/biomedicines6010019. Review.


Two Saporin-Containing Immunotoxins Specific for CD20 and CD22 Show Different Behavior in Killing Lymphoma Cells.

Polito L, Mercatelli D, Bortolotti M, Maiello S, Djemil A, Battelli MG, Bolognesi A.

Toxins (Basel). 2017 May 30;9(6). pii: E182. doi: 10.3390/toxins9060182.


Plant Toxin-Based Immunotoxins for Cancer Therapy: A Short Overview.

Polito L, Djemil A, Bortolotti M.

Biomedicines. 2016 Jun 1;4(2). pii: E12. doi: 10.3390/biomedicines4020012. Review.


Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.

Bolognesi A, Bortolotti M, Battelli MG, Polito L.

Molecules. 2017 Jan 27;22(2). pii: E206. doi: 10.3390/molecules22020206. Review.


Ribosome-Inactivating Proteins from Plants: A Historical Overview.

Bolognesi A, Bortolotti M, Maiello S, Battelli MG, Polito L.

Molecules. 2016 Nov 26;21(12). pii: E1627. Review.


Plants Producing Ribosome-Inactivating Proteins in Traditional Medicine.

Polito L, Bortolotti M, Maiello S, Battelli MG, Bolognesi A.

Molecules. 2016 Nov 18;21(11). pii: E1560. Review.


Xanthine Oxidoreductase in Drug Metabolism: Beyond a Role as a Detoxifying Enzyme.

Battelli MG, Polito L, Bortolotti M, Bolognesi A.

Curr Med Chem. 2016;23(35):4027-4036. Review.


High in Vitro Anti-Tumor Efficacy of Dimeric Rituximab/Saporin-S6 Immunotoxin.

Bortolotti M, Bolognesi A, Battelli MG, Polito L.

Toxins (Basel). 2016 Jun 21;8(6). pii: E192. doi: 10.3390/toxins8060192.


Apoptosis and necroptosis induced by stenodactylin in neuroblastoma cells can be completely prevented through caspase inhibition plus catalase or necrostatin-1.

Polito L, Bortolotti M, Pedrazzi M, Mercatelli D, Battelli MG, Bolognesi A.

Phytomedicine. 2016 Jan 15;23(1):32-41. doi: 10.1016/j.phymed.2015.11.006. Epub 2015 Dec 6.


Xanthine Oxidoreductase-Derived Reactive Species: Physiological and Pathological Effects.

Battelli MG, Polito L, Bortolotti M, Bolognesi A.

Oxid Med Cell Longev. 2016;2016:3527579. doi: 10.1155/2016/3527579. Epub 2015 Dec 28. Review.


Xanthine oxidoreductase in cancer: more than a differentiation marker.

Battelli MG, Polito L, Bortolotti M, Bolognesi A.

Cancer Med. 2016 Mar;5(3):546-57. doi: 10.1002/cam4.601. Epub 2015 Dec 21. Review.


Saporin-S6: a useful tool in cancer therapy.

Polito L, Bortolotti M, Mercatelli D, Battelli MG, Bolognesi A.

Toxins (Basel). 2013 Oct 7;5(10):1698-722. doi: 10.3390/toxins5101698. Review.


Protein synthesis inhibition activity by strawberry tissue protein extracts during plant life cycle and under biotic and abiotic stresses.

Polito L, Bortolotti M, Mercatelli D, Mancuso R, Baruzzi G, Faedi W, Bolognesi A.

Int J Mol Sci. 2013 Jul 25;14(8):15532-45. doi: 10.3390/ijms140815532.


Vernal keratoconjunctivitis-like disease in adults.

Leonardi A, Lazzarini D, Motterle L, Bortolotti M, Deligianni V, Curnow SJ, Bonini S, Fregona IA.

Am J Ophthalmol. 2013 May;155(5):796-803. doi: 10.1016/j.ajo.2012.11.018. Epub 2013 Jan 23.


Corneal confocal microscopy in patients with vernal keratoconjunctivitis.

Leonardi A, Lazzarini D, Bortolotti M, Piliego F, Midena E, Fregona I.

Ophthalmology. 2012 Mar;119(3):509-15. doi: 10.1016/j.ophtha.2011.09.018. Epub 2011 Dec 15.


Immunotoxins and other conjugates containing saporin-s6 for cancer therapy.

Polito L, Bortolotti M, Pedrazzi M, Bolognesi A.

Toxins (Basel). 2011 Jun;3(6):697-720. doi: 10.3390/toxins3060697. Epub 2011 Jun 22. Review.


Crystallization and preliminary X-ray diffraction data analysis of stenodactylin, a highly toxic type 2 ribosome-inactivating protein from Adenia stenodactyla.

Tosi G, Fermani S, Falini G, Polito L, Bortolotti M, Bolognesi A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):51-3. doi: 10.1107/S1744309109047654. Epub 2009 Dec 25.


ATG-saporin-S6 immunotoxin: a new potent and selective drug to eliminate activated lymphocytes and lymphoma cells.

Polito L, Bortolotti M, Farini V, Pedrazzi M, Tazzari PL, Bolognesi A.

Br J Haematol. 2009 Dec;147(5):710-8. doi: 10.1111/j.1365-2141.2009.07904.x. Epub 2009 Sep 18.


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