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Items: 1 to 20 of 59


The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers.

Fujiki H, Sueoka E, Watanabe T, Suganuma M.

J Cancer Res Clin Oncol. 2018 Dec;144(12):2339-2349. doi: 10.1007/s00432-018-2765-7. Epub 2018 Oct 20. Review.


Green Tea Catechin Is an Alternative Immune Checkpoint Inhibitor that Inhibits PD-L1 Expression and Lung Tumor Growth.

Rawangkan A, Wongsirisin P, Namiki K, Iida K, Kobayashi Y, Shimizu Y, Fujiki H, Suganuma M.

Molecules. 2018 Aug 18;23(8). pii: E2071. doi: 10.3390/molecules23082071.


Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2/TIS21 via downregulating cytoplasmic nucleolin expression.

Devanand P, Oya Y, Sundaramoorthy S, Song KY, Watanabe T, Kobayashi Y, Shimizu Y, Hong SA, Suganuma M, Lim IK.

Exp Mol Med. 2018 Feb 23;50(2):e449. doi: 10.1038/emm.2017.281.


Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells.

Fujiki H, Watanabe T, Sueoka E, Rawangkan A, Suganuma M.

Mol Cells. 2018 Feb 28;41(2):73-82. doi: 10.14348/molcells.2018.2227. Epub 2018 Jan 31. Review.


Cell softening in malignant progression of human lung cancer cells by activation of receptor tyrosine kinase AXL.

Iida K, Sakai R, Yokoyama S, Kobayashi N, Togo S, Yoshikawa HY, Rawangkan A, Namiki K, Suganuma M.

Sci Rep. 2017 Dec 19;7(1):17770. doi: 10.1038/s41598-017-18120-4.


Human cancer stem cells are a target for cancer prevention using (-)-epigallocatechin gallate.

Fujiki H, Sueoka E, Rawangkan A, Suganuma M.

J Cancer Res Clin Oncol. 2017 Dec;143(12):2401-2412. doi: 10.1007/s00432-017-2515-2. Epub 2017 Sep 23. Review.


A single-round selection of selective DNA aptamers for mammalian cells by polymer-enhanced capillary transient isotachophoresis.

Hirose K, Tsuchida M, Asakura H, Wakui K, Yoshimoto K, Iida K, Sato M, Shibukawa M, Suganuma M, Saito S.

Analyst. 2017 Oct 23;142(21):4030-4038. doi: 10.1039/c7an00909g.


Adsorption of galloyl catechin aggregates significantly modulates membrane mechanics in the absence of biochemical cues.

Matsuzaki T, Ito H, Chevyreva V, Makky A, Kaufmann S, Okano K, Kobayashi N, Suganuma M, Nakabayashi S, Yoshikawa HY, Tanaka M.

Phys Chem Chem Phys. 2017 Aug 2;19(30):19937-19947. doi: 10.1039/c7cp02771k.


Phorbol esters in seed oil of Jatropha curcas L. (saboodam in Thai) and their association with cancer prevention: from the initial investigation to the present topics.

Fujiki H, Suttajit M, Rawangkan A, Iida K, Limtrakul P, Umsumarng S, Suganuma M.

J Cancer Res Clin Oncol. 2017 Aug;143(8):1359-1369. doi: 10.1007/s00432-017-2341-6. Epub 2017 Jan 25. Review.


Down-regulation of histone deacetylase 4, -5 and -6 as a mechanism of synergistic enhancement of apoptosis in human lung cancer cells treated with the combination of a synthetic retinoid, Am80 and green tea catechin.

Oya Y, Mondal A, Rawangkan A, Umsumarng S, Iida K, Watanabe T, Kanno M, Suzuki K, Li Z, Kagechika H, Shudo K, Fujiki H, Suganuma M.

J Nutr Biochem. 2017 Apr;42:7-16. doi: 10.1016/j.jnutbio.2016.12.015. Epub 2017 Jan 8.


Biophysical Approach to Mechanisms of Cancer Prevention and Treatment with Green Tea Catechins.

Suganuma M, Takahashi A, Watanabe T, Iida K, Matsuzaki T, Yoshikawa HY, Fujiki H.

Molecules. 2016 Nov 18;21(11). pii: E1566. Review.


Regulations of Reversal of Senescence by PKC Isozymes in Response to 12-O-Tetradecanoylphorbol-13-Acetate via Nuclear Translocation of pErk1/2.

Lee YY, Ryu MS, Kim HS, Suganuma M, Song KY, Lim IK.

Mol Cells. 2016 Mar;39(3):266-79. doi: 10.14348/molcells.2016.2362. Epub 2016 Feb 24.


Quantitative Evaluation of Cancer Cell Adhesion to Self-Assembled Monolayer-Patterned Substrates by Reflection Interference Contrast Microscopy.

Matsuzaki T, Ito K, Masuda K, Kakinuma E, Sakamoto R, Iketaki K, Yamamoto H, Suganuma M, Kobayashi N, Nakabayashi S, Tanii T, Yoshikawa HY.

J Phys Chem B. 2016 Feb 25;120(7):1221-7. doi: 10.1021/acs.jpcb.5b11870. Epub 2016 Feb 16.


Primary cancer prevention by green tea, and tertiary cancer prevention by the combination of green tea catechins and anticancer compounds.

Fujiki H, Sueoka E, Watanabe T, Suganuma M.

J Cancer Prev. 2015 Mar;20(1):1-4. doi: 10.15430/JCP.2015.20.1.1. Review.


Highlights of the Twelfth Japan-Korea Joint Symposium on Cancer and Ageing Research.

Suganuma M, Park TJ, Sueoka E, Iida K, Tanaka Y.

J Cancer Res Clin Oncol. 2015 Nov;141(11):1953-61. doi: 10.1007/s00432-015-1959-5. Epub 2015 Mar 29.


Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds.

Fujiki H, Sueoka E, Watanabe T, Suganuma M.

J Cancer Res Clin Oncol. 2015 Sep;141(9):1511-22. doi: 10.1007/s00432-014-1899-5. Epub 2014 Dec 28. Review.


Green tea aroma fraction reduces β-amyloid peptide-induced toxicity in Caenorhabditis elegans transfected with human β-amyloid minigene.

Takahashi A, Watanabe T, Fujita T, Hasegawa T, Saito M, Suganuma M.

Biosci Biotechnol Biochem. 2014;78(7):1206-11. doi: 10.1080/09168451.2014.921553. Epub 2014 Jun 12.


Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands.

Fujiki H, Watanabe T, Suganuma M.

J Cancer Res Clin Oncol. 2014 May;140(5):689-99. doi: 10.1007/s00432-014-1587-5. Epub 2014 Jan 28.


High Contrast Visualization of Cell-Hydrogel Contact by Advanced Interferometric Optical Microscopy.

Matsuzaki T, Sazaki G, Suganuma M, Watanabe T, Yamazaki T, Tanaka M, Nakabayashi S, Yoshikawa HY.

J Phys Chem Lett. 2014 Jan 2;5(1):253-7. doi: 10.1021/jz402463u. Epub 2013 Dec 23.


Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate.

Takahashi A, Watanabe T, Mondal A, Suzuki K, Kurusu-Kanno M, Li Z, Yamazaki T, Fujiki H, Suganuma M.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):1-6. doi: 10.1016/j.bbrc.2013.10.094. Epub 2013 Nov 21.


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