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Items: 15


Metabolic activation triggered by cAMP in MCF-7 cells generates lethal vulnerability to combined oxamate/etomoxir.

Manerba M, Govoni M, Manet I, Leale A, Comparone A, Di Stefano G.

Biochim Biophys Acta Gen Subj. 2019 Jul;1863(7):1177-1186. doi: 10.1016/j.bbagen.2019.04.008. Epub 2019 Apr 11.


The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells.

Manerba M, Di Ianni L, Govoni M, Comparone A, Di Stefano G.

PLoS One. 2018 Aug 23;13(8):e0202588. doi: 10.1371/journal.pone.0202588. eCollection 2018.


Epigallocatechin-3-gallate and 6-OH-11-O-Hydroxyphenanthrene Limit BE(2)-C Neuroblastoma Cell Growth and Neurosphere Formation In Vitro.

Farabegoli F, Govoni M, Spisni E, Papi A.

Nutrients. 2018 Aug 22;10(9). pii: E1141. doi: 10.3390/nu10091141.


LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells.

Manerba M, Di Ianni L, Govoni M, Roberti M, Recanatini M, Di Stefano G.

Eur J Pharm Sci. 2017 Jul 15;105:91-98. doi: 10.1016/j.ejps.2017.05.015. Epub 2017 May 10.


EGFR inhibition by (-)-epigallocatechin-3-gallate and IIF treatments reduces breast cancer cell invasion.

Farabegoli F, Govoni M, Spisni E, Papi A.

Biosci Rep. 2017 May 17;37(3). pii: BSR20170168. doi: 10.1042/BSR20170168. Print 2017 Jun 30.


Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.

Manerba M, Di Ianni L, Govoni M, Roberti M, Recanatini M, Di Stefano G.

Eur J Pharm Sci. 2017 Jan 1;96:37-44. doi: 10.1016/j.ejps.2016.09.014. Epub 2016 Sep 10.


Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate.

Brighenti E, Giannone FA, Fornari F, Onofrillo C, Govoni M, Montanaro L, Treré D, Derenzini M.

Oncotarget. 2016 Sep 27;7(39):63226-63241. doi: 10.18632/oncotarget.11441.


Epigallocatechin-3-gallate Increases RXRγ-mediated Pro-apoptotic and Anti-invasive Effects in Gastrointestinal Cancer Cell Lines.

Papi A, Govoni M, Ciavarella C, Spisni E, Orlandi M, Farabegoli F.

Curr Cancer Drug Targets. 2016;16(4):373-85.


JHDM1B expression regulates ribosome biogenesis and cancer cell growth in a p53 dependent manner.

Penzo M, Casoli L, Pollutri D, Sicuro L, Ceccarelli C, Santini D, Taffurelli M, Govoni M, Brina D, Trerè D, Montanaro L.

Int J Cancer. 2015 Mar 1;136(5):E272-81. doi: 10.1002/ijc.29240. Epub 2014 Oct 10.


A RXR ligand 6-OH-11-O-hydroxyphenanthrene with antitumour properties enhances (-)-epigallocatechin-3-gallate activity in three human breast carcinoma cell lines.

Farabegoli F, Govoni M, Ciavarella C, Orlandi M, Papi A.

Biomed Res Int. 2014;2014:853086. doi: 10.1155/2014/853086. Epub 2014 Jun 11.


Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.

Vettraino M, Manerba M, Govoni M, Di Stefano G.

Anticancer Drugs. 2013 Sep;24(8):862-70. doi: 10.1097/CAD.0b013e328363ae50.


Location of rRNA transcription to the nucleolar components: disappearance of the fibrillar centers in nucleoli of regenerating rat hepatocytes.

Montanaro L, Govoni M, Orrico C, Treré D, Derenzini M.

Cell Struct Funct. 2011;36(1):49-56. Epub 2011 Feb 9.


The hydroxy-methyl-glutaryl CoA reductase promoter polymorphism is associated with Alzheimer's risk and cognitive deterioration.

Porcellini E, Calabrese E, Guerini F, Govoni M, Chiappelli M, Tumini E, Morgan K, Chappell S, Kalsheker N, Franceschi M, Licastro F.

Neurosci Lett. 2007 Apr 6;416(1):66-70. Epub 2007 Jan 25.


Key role of the achievement of an appropriate ribosomal RNA complement for G1-S phase transition in H4-II-E-C3 rat hepatoma cells.

Derenzini M, Montanaro L, Chillà A, Tosti E, Vici M, Barbieri S, Govoni M, Mazzini G, Treré D.

J Cell Physiol. 2005 Feb;202(2):483-91.


Increased mortality rate and not impaired ribosomal biogenesis is responsible for proliferative defect in dyskeratosis congenita cell lines.

Montanaro L, Chillà A, Trerè D, Pession A, Govoni M, Tazzari PL, Derenzini M.

J Invest Dermatol. 2002 Jan;118(1):193-8.

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