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Items: 9


Exogenous 3-Iodothyronamine Rescues the Entorhinal Cortex from ╬▓-Amyloid Toxicity.

Accorroni A, Rutigliano G, Sabatini M, Frascarelli S, Bors├▓ M, Novelli E, Bandini L, Ghelardoni S, Saba A, Zucchi R, Origlia N.

Thyroid. 2019 Dec 20. doi: 10.1089/thy.2019.0255. [Epub ahead of print]


Lipolytic Effects of 3-Iodothyronamine (T1AM) and a Novel Thyronamine-Like Analog SG-2 through the AMPK Pathway.

Rogowski M, Bellusci L, Sabatini M, Rapposelli S, Rahman SM, Chiellini G, Assadi-Porter FM.

Int J Mol Sci. 2019 Aug 20;20(16). pii: E4054. doi: 10.3390/ijms20164054.


Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression.

Assadi-Porter FM, Reiland H, Sabatini M, Lorenzini L, Carnicelli V, Rogowski M, Selen Alpergin ES, Tonelli M, Ghelardoni S, Saba A, Zucchi R, Chiellini G.

Int J Mol Sci. 2018 May 22;19(5). pii: E1535. doi: 10.3390/ijms19051535.


New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection.

Bellusci L, Laurino A, Sabatini M, Sestito S, Lenzi P, Raimondi L, Rapposelli S, Biagioni F, Fornai F, Salvetti A, Rossi L, Zucchi R, Chiellini G.

Front Pharmacol. 2017 Dec 12;8:905. doi: 10.3389/fphar.2017.00905. eCollection 2017.


Metabolic profiling reveals reprogramming of lipid metabolic pathways in treatment of polycystic ovary syndrome with 3-iodothyronamine.

Selen Alpergin ES, Bolandnazar Z, Sabatini M, Rogowski M, Chiellini G, Zucchi R, Assadi-Porter FM.

Physiol Rep. 2017 Jan;5(1). pii: e13097. doi: 10.14814/phy2.13097.


Thyronamines and Analogues - The Route from Rediscovery to Translational Research on Thyronergic Amines.

Chiellini G, Bellusci L, Sabatini M, Zucchi R.

Mol Cell Endocrinol. 2017 Dec 15;458:149-155. doi: 10.1016/j.mce.2017.01.002. Epub 2017 Jan 6. Review.


Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study.

Chiellini G, Nesi G, Sestito S, Chiarugi S, Runfola M, Espinoza S, Sabatini M, Bellusci L, Laurino A, Cichero E, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S.

J Med Chem. 2016 Nov 10;59(21):9825-9836. Epub 2016 Oct 21.


Effect of Hypothyroidism and Hyperthyroidism on Tissue Thyroid Hormone Concentrations in Rat.

Donzelli R, Colligiani D, Kusmic C, Sabatini M, Lorenzini L, Accorroni A, Nannipieri M, Saba A, Iervasi G, Zucchi R.

Eur Thyroid J. 2016 Mar;5(1):27-34. doi: 10.1159/000443523. Epub 2016 Feb 26.


Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists.

Chiellini G, Nesi G, Digiacomo M, Malvasi R, Espinoza S, Sabatini M, Frascarelli S, Laurino A, Cichero E, Macchia M, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S.

J Med Chem. 2015 Jun 25;58(12):5096-107. doi: 10.1021/acs.jmedchem.5b00526. Epub 2015 Jun 5.


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