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Items: 8

1.

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs.

Lindner S, Steinebach C, Kehm H, Mangold M, Gütschow M, Krönke J.

J Vis Exp. 2019 May 15;(147). doi: 10.3791/59472.

PMID:
31157769
2.

Engineering preferentially-aligned nitrogen-vacancy centre ensembles in CVD grown diamond.

Osterkamp C, Mangold M, Lang J, Balasubramanian P, Teraji T, Naydenov B, Jelezko F.

Sci Rep. 2019 Apr 8;9(1):5786. doi: 10.1038/s41598-019-42314-7.

3.

Matriptase-2: monitoring and inhibiting its proteolytic activity.

Gitlin-Domagalska A, Mangold M, Dębowski D, Ptaszyńska N, Łęgowska A, Gütschow M, Rolka K.

Future Med Chem. 2018 Dec 6. doi: 10.4155/fmc-2018-0346. [Epub ahead of print]

PMID:
30518272
4.

A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2.

Mangold M, Gütschow M, Stirnberg M.

Pharmaceuticals (Basel). 2018 May 21;11(2). pii: E49. doi: 10.3390/ph11020049.

5.

A Fluorescent-Labeled Phosphono Bisbenzguanidine As an Activity-Based Probe for Matriptase.

Häußler D, Schulz-Fincke AC, Beckmann AM, Keils A, Gilberg E, Mangold M, Bajorath J, Stirnberg M, Steinmetzer T, Gütschow M.

Chemistry. 2017 Apr 19;23(22):5205-5209. doi: 10.1002/chem.201700319. Epub 2017 Mar 28.

PMID:
28370501
6.

Phosphono Bisbenzguanidines as Irreversible Dipeptidomimetic Inhibitors and Activity-Based Probes of Matriptase-2.

Häußler D, Mangold M, Furtmann N, Braune A, Blaut M, Bajorath J, Stirnberg M, Gütschow M.

Chemistry. 2016 Jun 13;22(25):8525-35. doi: 10.1002/chem.201600206. Epub 2016 May 23.

PMID:
27214780
7.

The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.

Beckmann AM, Glebov K, Walter J, Merkel O, Mangold M, Schmidt F, Becker-Pauly C, Gütschow M, Stirnberg M.

Biol Chem. 2016 Aug 1;397(8):777-90. doi: 10.1515/hsz-2015-0263.

PMID:
27078672
8.

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding.

Jäckle F, Schmidt F, Wichert R, Arnold P, Prox J, Mangold M, Ohler A, Pietrzik CU, Koudelka T, Tholey A, Gütschow M, Stirnberg M, Becker-Pauly C.

Biochem J. 2015 Aug 15;470(1):91-103. doi: 10.1042/BJ20141417. Epub 2015 Jun 15.

PMID:
26251449

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