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Items: 1 to 20 of 27

1.

Fungal Kti12 proteins display unusual linker regions and unique ATPase p-loops.

Krutyhołowa R, Reinhardt-Tews A, Chramiec-Głąbik A, Breunig KD, Glatt S.

Curr Genet. 2020 Mar 31. doi: 10.1007/s00294-020-01070-2. [Epub ahead of print]

PMID:
32236652
2.

Speckle tracking derived reference values of myocardial deformation and impact of cardiovascular risk factors - Results from the population-based STAAB cohort study.

Morbach C, Walter BN, Breunig M, Liu D, Tiffe T, Wagner M, Gelbrich G, Heuschmann PU, Störk S; STAAB consortium.

PLoS One. 2019 Sep 12;14(9):e0221888. doi: 10.1371/journal.pone.0221888. eCollection 2019.

3.

Molecular basis of tRNA recognition by the Elongator complex.

Dauden MI, Jaciuk M, Weis F, Lin TY, Kleindienst C, Abbassi NEH, Khatter H, Krutyhołowa R, Breunig KD, Kosinski J, Müller CW, Glatt S.

Sci Adv. 2019 Jul 10;5(7):eaaw2326. doi: 10.1126/sciadv.aaw2326. eCollection 2019 Jul.

4.

Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator.

Krutyhołowa R, Hammermeister A, Zabel R, Abdel-Fattah W, Reinhardt-Tews A, Helm M, Stark MJR, Breunig KD, Schaffrath R, Glatt S.

Nucleic Acids Res. 2019 May 21;47(9):4814-4830. doi: 10.1093/nar/gkz190.

5.

TGFβ1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer.

Breunig C, Erdem N, Bott A, Greiwe JF, Reinz E, Bernhardt S, Giacomelli C, Wachter A, Kanthelhardt EJ, Beißbarth T, Vetter M, Wiemann S.

Mol Oncol. 2018 Sep;12(9):1447-1463. doi: 10.1002/1878-0261.12355. Epub 2018 Jul 30.

6.

Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator.

Mehlgarten C, Prochaska H, Hammermeister A, Abdel-Fattah W, Wagner M, Krutyhołowa R, Jun SE, Kim GT, Glatt S, Breunig KD, Stark MJR, Schaffrath R.

Toxins (Basel). 2017 Sep 5;9(9). pii: E272. doi: 10.3390/toxins9090272.

7.

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease.

HPS3/TIMI55–REVEAL Collaborative Group, Bowman L, Hopewell JC, Chen F, Wallendszus K, Stevens W, Collins R, Wiviott SD, Cannon CP, Braunwald E, Sammons E, Landray MJ.

N Engl J Med. 2017 Sep 28;377(13):1217-1227. doi: 10.1056/NEJMoa1706444. Epub 2017 Aug 28.

8.

Architecture of the yeast Elongator complex.

Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW.

EMBO Rep. 2017 Feb;18(2):264-279. doi: 10.15252/embr.201643353. Epub 2016 Dec 14.

9.

Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.

Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B Jr, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A.

Gut. 2017 Mar;66(3):473-486. doi: 10.1136/gutjnl-2016-312423. Epub 2016 Sep 15.

10.

Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi.

Glatt S, Zabel R, Kolaj-Robin O, Onuma OF, Baudin F, Graziadei A, Taverniti V, Lin TY, Baymann F, Seraphin B, Breunig KD, Müller CW.

Nat Struct Mol Biol. 2016 Sep;23(9):794-802. doi: 10.1038/nsmb.3265. Epub 2016 Jul 25.

11.

The role of myosin 1c and myosin 1b in surfactant exocytosis.

Kittelberger N, Breunig M, Martin R, Knölker HJ, Miklavc P.

J Cell Sci. 2016 Apr 15;129(8):1685-96. doi: 10.1242/jcs.181313. Epub 2016 Mar 3.

12.

Divergent Evolution of the Transcriptional Network Controlled by Snf1-Interacting Protein Sip4 in Budding Yeasts.

Mehlgarten C, Krijger JJ, Lemnian I, Gohr A, Kasper L, Diesing AK, Grosse I, Breunig KD.

PLoS One. 2015 Oct 6;10(10):e0139464. doi: 10.1371/journal.pone.0139464. eCollection 2015.

13.

Structure of the Kti11/Kti13 heterodimer and its double role in modifications of tRNA and eukaryotic elongation factor 2.

Glatt S, Zabel R, Vonkova I, Kumar A, Netz DJ, Pierik AJ, Rybin V, Lill R, Gavin AC, Balbach J, Breunig KD, Müller CW.

Structure. 2015 Jan 6;23(1):149-160. doi: 10.1016/j.str.2014.11.008. Epub 2014 Dec 24.

14.

A new system for comparative functional genomics of Saccharomyces yeasts.

Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D, Bauerle C, Bisaria N, Bradley PH, Breunig JS, Bush E, Cappel D, Capra E, Chen W, Clore J, Combs PA, Doucette C, Demuren O, Fellowes P, Freeman S, Frenkel E, Gadala-Maria D, Gawande R, Glass D, Grossberg S, Gupta A, Hammonds-Odie L, Hoisos A, Hsi J, Hsu YH, Inukai S, Karczewski KJ, Ke X, Kojima M, Leachman S, Lieber D, Liebowitz A, Liu J, Liu Y, Martin T, Mena J, Mendoza R, Myhrvold C, Millian C, Pfau S, Raj S, Rich M, Rokicki J, Rounds W, Salazar M, Salesi M, Sharma R, Silverman S, Singer C, Sinha S, Staller M, Stern P, Tang H, Weeks S, Weidmann M, Wolf A, Young C, Yuan J, Crutchfield C, McClean M, Murphy CT, Llinás M, Botstein D, Troyanskaya OG, Dunham MJ.

Genetics. 2013 Sep;195(1):275-87. doi: 10.1534/genetics.113.152918. Epub 2013 Jul 12.

15.

Production of polyomavirus-like particles in a Klgal80 knockout strain of the yeast Kluyveromyces lactis.

Simon C, Schaepe S, Breunig K, Lilie H.

Prep Biochem Biotechnol. 2013;43(2):217-35. doi: 10.1080/10826068.2012.750613.

PMID:
23302109
16.

Protective vaccination against infectious bursal disease virus with whole recombinant Kluyveromyces lactis yeast expressing the viral VP2 subunit.

Arnold M, Durairaj V, Mundt E, Schulze K, Breunig KD, Behrens SE.

PLoS One. 2012;7(9):e42870. Epub 2012 Sep 14.

17.

A novel, lactase-based selection and strain improvement strategy for recombinant protein expression in Kluyveromyces lactis.

Krijger JJ, Baumann J, Wagner M, Schulze K, Reinsch C, Klose T, Onuma OF, Simon C, Behrens SE, Breunig KD.

Microb Cell Fact. 2012 Aug 20;11:112. doi: 10.1186/1475-2859-11-112.

18.

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.

Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, Wanner C, Krane V, Cass A, Craig J, Neal B, Jiang L, Hooi LS, Levin A, Agodoa L, Gaziano M, Kasiske B, Walker R, Massy ZA, Feldt-Rasmussen B, Krairittichai U, Ophascharoensuk V, Fellström B, Holdaas H, Tesar V, Wiecek A, Grobbee D, de Zeeuw D, Grönhagen-Riska C, Dasgupta T, Lewis D, Herrington W, Mafham M, Majoni W, Wallendszus K, Grimm R, Pedersen T, Tobert J, Armitage J, Baxter A, Bray C, Chen Y, Chen Z, Hill M, Knott C, Parish S, Simpson D, Sleight P, Young A, Collins R; SHARP Investigators.

Lancet. 2011 Jun 25;377(9784):2181-92. doi: 10.1016/S0140-6736(11)60739-3. Epub 2011 Jun 12.

19.

Evolutionary aspects of a genetic network: studying the lactose/galactose regulon of Kluyveromyces lactis.

Anders A, Breunig KD.

Methods Mol Biol. 2011;734:259-77. doi: 10.1007/978-1-61779-086-7_13.

PMID:
21468994
20.

Elongator function in tRNA wobble uridine modification is conserved between yeast and plants.

Mehlgarten C, Jablonowski D, Wrackmeyer U, Tschitschmann S, Sondermann D, Jäger G, Gong Z, Byström AS, Schaffrath R, Breunig KD.

Mol Microbiol. 2010 Jun 1;76(5):1082-94. doi: 10.1111/j.1365-2958.2010.07163.x. Epub 2010 Apr 14. Erratum in: Mol Microbiol. 2010 Jul;77(2):531.

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