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Items: 1 to 20 of 58

1.

Synthetic Semiflexible and Bioactive Brushes.

Voerman D, Schluck M, Weiden J, Joosten B, Eggermont LJ, van den Eijnde T, Ignacio B, Cambi A, Figdor CG, Kouwer PHJ, Verdoes M, Hammink R, Rowan AE.

Biomacromolecules. 2019 Jul 8;20(7):2587-2597. doi: 10.1021/acs.biomac.9b00385. Epub 2019 Jun 13.

2.

Biomaterial-Based Activation and Expansion of Tumor-Specific T Cells.

Schluck M, Hammink R, Figdor CG, Verdoes M, Weiden J.

Front Immunol. 2019 May 3;10:931. doi: 10.3389/fimmu.2019.00931. eCollection 2019.

3.

Attacking Tumors From All Sides: Personalized Multiplex Vaccines to Tackle Intratumor Heterogeneity.

Fennemann FL, de Vries IJM, Figdor CG, Verdoes M.

Front Immunol. 2019 Apr 16;10:824. doi: 10.3389/fimmu.2019.00824. eCollection 2019.

4.

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.

Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN.

Nat Med. 2019 Apr;25(4):612-619. doi: 10.1038/s41591-019-0356-z. Epub 2019 Mar 4.

PMID:
30833751
5.

The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K.

Mons E, Jansen IDC, Loboda J, van Doodewaerd BR, Hermans J, Verdoes M, van Boeckel CAA, van Veelen PA, Turk B, Turk D, Ovaa H.

J Am Chem Soc. 2019 Feb 27;141(8):3507-3514. doi: 10.1021/jacs.8b11027. Epub 2019 Feb 14.

6.

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation.

Baranov MV, Bianchi F, Schirmacher A, van Aart MAC, Maassen S, Muntjewerff EM, Dingjan I, Ter Beest M, Verdoes M, Keyser SGL, Bertozzi CR, Diederichsen U, van den Bogaart G.

iScience. 2019 Jan 25;11:160-177. doi: 10.1016/j.isci.2018.12.015. Epub 2018 Dec 20.

7.

Molecular Repolarisation of Tumour-Associated Macrophages.

van Dalen FJ, van Stevendaal MHME, Fennemann FL, Verdoes M, Ilina O.

Molecules. 2018 Dec 20;24(1). pii: E9. doi: 10.3390/molecules24010009. Review.

8.

Endolysosomal-Escape Nanovaccines through Adjuvant-Induced Tumor Antigen Assembly for Enhanced Effector CD8+ T Cell Activation.

Qiu L, Valente M, Dolen Y, Jäger E, Beest MT, Zheng L, Figdor CG, Verdoes M.

Small. 2018 Apr;14(15):e1703539. doi: 10.1002/smll.201703539. Epub 2018 Mar 1.

PMID:
29493121
9.

Toll-like Receptor Agonist Conjugation: A Chemical Perspective.

Ignacio BJ, Albin TJ, Esser-Kahn AP, Verdoes M.

Bioconjug Chem. 2018 Mar 21;29(3):587-603. doi: 10.1021/acs.bioconjchem.7b00808. Epub 2018 Feb 16. Review.

PMID:
29378134
10.

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

Oortveld MAW, van Vlijmen-Willems IMJJ, Kersten FFJ, Cheng T, Verdoes M, van Erp PEJ, Verbeek S, Reinheckel T, Hendriks WJAJ, Schalkwijk J, Zeeuwen PLJM.

FASEB J. 2017 Oct;31(10):4286-4294. doi: 10.1096/fj.201700267R. Epub 2017 Jun 8.

11.

A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.

Schnettger L, Rodgers A, Repnik U, Lai RP, Pei G, Verdoes M, Wilkinson RJ, Young DB, Gutierrez MG.

Cell Host Microbe. 2017 May 10;21(5):619-628.e5. doi: 10.1016/j.chom.2017.04.004.

12.

Live Cell Imaging and Profiling of Cysteine Cathepsin Activity Using a Quenched Activity-Based Probe.

Edgington-Mitchell LE, Bogyo M, Verdoes M.

Methods Mol Biol. 2017;1491:145-159.

PMID:
27778287
13.

Legumain is activated in macrophages during pancreatitis.

Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, Storz P, Halangk W, Bogyo M, Bunnett NW.

Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G548-60. doi: 10.1152/ajpgi.00047.2016. Epub 2016 Aug 11.

14.

Bifunctional Probes of Cathepsin Protease Activity and pH Reveal Alterations in Endolysosomal pH during Bacterial Infection.

Sanman LE, van der Linden WA, Verdoes M, Bogyo M.

Cell Chem Biol. 2016 Jul 21;23(7):793-804. doi: 10.1016/j.chembiol.2016.05.019. Epub 2016 Jul 14.

15.

Dual-Modality Activity-Based Probes as Molecular Imaging Agents for Vascular Inflammation.

Withana NP, Saito T, Ma X, Garland M, Liu C, Kosuge H, Amsallem M, Verdoes M, Ofori LO, Fischbein M, Arakawa M, Cheng Z, McConnell MV, Bogyo M.

J Nucl Med. 2016 Oct;57(10):1583-1590. Epub 2016 May 19.

16.

Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes.

Withana NP, Ma X, McGuire HM, Verdoes M, van der Linden WA, Ofori LO, Zhang R, Li H, Sanman LE, Wei K, Yao S, Wu P, Li F, Huang H, Xu Z, Wolters PJ, Rosen GD, Collard HR, Zhu Z, Cheng Z, Bogyo M.

Sci Rep. 2016 Jan 22;6:19755. doi: 10.1038/srep19755.

17.

Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes.

Withana NP, Garland M, Verdoes M, Ofori LO, Segal E, Bogyo M.

Nat Protoc. 2016 Jan;11(1):184-91. doi: 10.1038/nprot.2016.004. Epub 2015 Dec 30.

PMID:
26716706
18.

Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.

Edgington-Mitchell LE, Rautela J, Duivenvoorden HM, Jayatilleke KM, van der Linden WA, Verdoes M, Bogyo M, Parker BS.

Oncotarget. 2015 Sep 29;6(29):27008-22. doi: 10.18632/oncotarget.4714.

19.

Design of Protease Activated Optical Contrast Agents That Exploit a Latent Lysosomotropic Effect for Use in Fluorescence-Guided Surgery.

Ofori LO, Withana NP, Prestwood TR, Verdoes M, Brady JJ, Winslow MM, Sorger J, Bogyo M.

ACS Chem Biol. 2015 Sep 18;10(9):1977-88. doi: 10.1021/acschembio.5b00205. Epub 2015 Jun 24.

20.

Regulation of immunoproteasome function in the lung.

Keller IE, Vosyka O, Takenaka S, Kloß A, Dahlmann B, Willems LI, Verdoes M, Overkleeft HS, Marcos E, Adnot S, Hauck SM, Ruppert C, Günther A, Herold S, Ohno S, Adler H, Eickelberg O, Meiners S.

Sci Rep. 2015 May 19;5:10230. doi: 10.1038/srep10230.

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