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Items: 1 to 20 of 34

1.

Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors.

Serafini M, Torre E, Aprile S, Massarotti A, Fallarini S, Pirali T.

Molecules. 2019 May 15;24(10). pii: E1874. doi: 10.3390/molecules24101874.

2.

Acute myeloid leukaemia niche regulates response to L-asparaginase.

Michelozzi IM, Granata V, De Ponti G, Alberti G, Tomasoni C, Antolini L, Gambacorti-Passerini C, Gentner B, Dazzi F, Biondi A, Coliva T, Rizzari C, Pievani A, Serafini M.

Br J Haematol. 2019 May 1. doi: 10.1111/bjh.15920. [Epub ahead of print]

PMID:
31044436
3.

Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.

Pirali T, Galli U, Serafini M, Griglio A, Genazzani AA, Tron GC.

Methods Mol Biol. 2019;1987:207-221. doi: 10.1007/978-1-4939-9446-5_13.

PMID:
31028682
4.

Hematopoietic Stem Cell Transplantation for Mucopolysaccharidoses: Past, Present, and Future.

Taylor M, Khan S, Stapleton M, Wang J, Chen J, Wynn R, Yabe H, Chinen Y, Boelens JJ, Mason RW, Kubaski F, Horovitz DDG, Barth AL, Serafini M, Bernardo ME, Kobayashi H, Orii KE, Suzuki Y, Orii T, Tomatsu S.

Biol Blood Marrow Transplant. 2019 Feb 14. pii: S1083-8791(19)30137-5. doi: 10.1016/j.bbmt.2019.02.012. [Epub ahead of print] Review.

PMID:
30772512
5.

Applications of Deuterium in Medicinal Chemistry.

Pirali T, Serafini M, Cargnin S, Genazzani AA.

J Med Chem. 2019 Jun 13;62(11):5276-5297. doi: 10.1021/acs.jmedchem.8b01808. Epub 2019 Jan 25.

PMID:
30640460
6.

Arynes and isocyanides: Two close-knit partners in multicomponent reactions.

Serafini M, Pirali T.

Drug Discov Today Technol. 2018 Nov;29:35-41. doi: 10.1016/j.ddtec.2018.06.007. Epub 2018 Jul 2. Review.

PMID:
30471672
7.

Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches.

Fraldi A, Serafini M, Sorrentino NC, Gentner B, Aiuti A, Bernardo ME.

Ital J Pediatr. 2018 Nov 16;44(Suppl 2):130. doi: 10.1186/s13052-018-0565-y. Review.

8.

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.

Riva B, Griglio A, Serafini M, Cordero-Sanchez C, Aprile S, Di Paola R, Gugliandolo E, Alansary D, Biocotino I, Lim D, Grosa G, Galli U, Niemeyer B, Sorba G, Canonico PL, Cuzzocrea S, Genazzani AA, Pirali T.

J Med Chem. 2018 Nov 8;61(21):9756-9783. doi: 10.1021/acs.jmedchem.8b01512. Epub 2018 Oct 30.

PMID:
30347159
9.

Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.

Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzalez-Rodriguez S, Butron L, Devesa I, Fernandez-Carvajal A, Pirali T, Ferrer-Montiel A.

J Med Chem. 2018 May 24;61(10):4436-4455. doi: 10.1021/acs.jmedchem.8b00109. Epub 2018 May 15.

PMID:
29722529
10.

A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies.

Griglio A, Torre E, Serafini M, Bianchi A, Schmid R, Coda Zabetta G, Massarotti A, Sorba G, Pirali T, Fallarini S.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):651-657. doi: 10.1016/j.bmcl.2018.01.032. Epub 2018 Feb 2.

PMID:
29398544
11.

Thrombosis after liver transplantation for hepatocellular carcinoma.

Martinelli I, Ponziani FR, Maino A, Bhoori S, Abbattista M, Maggi U, De Feo TM, Bucciarelli P, Artoni A, Longhi E, Serafini M, Rossi G, Mazzaferro V.

PLoS One. 2017 Oct 26;12(10):e0186699. doi: 10.1371/journal.pone.0186699. eCollection 2017.

12.

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.

Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano AC, Monfregola J, De Gennaro E, Nusco E, Azario I, Lanzara C, Serafini M, Levine B, Ballabio A, Settembre C.

J Clin Invest. 2017 Oct 2;127(10):3717-3729. doi: 10.1172/JCI94130. Epub 2017 Sep 5.

13.

Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs.

Pirali T, Ciraolo E, Aprile S, Massarotti A, Berndt A, Griglio A, Serafini M, Mercalli V, Landoni C, Campa CC, Margaria JP, Silva RL, Grosa G, Sorba G, Williams R, Hirsch E, Tron GC.

ChemMedChem. 2017 Sep 21;12(18):1542-1554. doi: 10.1002/cmdc.201700340. Epub 2017 Aug 31.

14.

Neonatal umbilical cord blood transplantation halts skeletal disease progression in the murine model of MPS-I.

Azario I, Pievani A, Del Priore F, Antolini L, Santi L, Corsi A, Cardinale L, Sawamoto K, Kubaski F, Gentner B, Bernardo ME, Valsecchi MG, Riminucci M, Tomatsu S, Aiuti A, Biondi A, Serafini M.

Sci Rep. 2017 Aug 25;7(1):9473. doi: 10.1038/s41598-017-09958-9.

15.

An aryne-based three-component access to α-aroylamino amides.

Serafini M, Griglio A, Viarengo S, Aprile S, Pirali T.

Org Biomol Chem. 2017 Aug 9;15(31):6604-6612. doi: 10.1039/c7ob01715d.

PMID:
28752162
16.

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo.

Pievani A, Sacchetti B, Corsi A, Rambaldi B, Donsante S, Scagliotti V, Vergani P, Remoli C, Biondi A, Robey PG, Riminucci M, Serafini M.

Development. 2017 Mar 15;144(6):1035-1044. doi: 10.1242/dev.142836.

17.

Bone marrow mesenchymal stromal cells induce nitric oxide synthase-dependent differentiation of CD11b+ cells that expedite hematopoietic recovery.

Trento C, Marigo I, Pievani A, Galleu A, Dolcetti L, Wang CY, Serafini M, Bronte V, Dazzi F.

Haematologica. 2017 May;102(5):818-825. doi: 10.3324/haematol.2016.155390. Epub 2017 Feb 9.

18.

Human aplastic anaemia-derived mesenchymal stromal cells form functional haematopoietic stem cell niche in vivo.

Michelozzi IM, Pievani A, Pagni F, Antolini L, Verna M, Corti P, Rovelli A, Riminucci M, Dazzi F, Biondi A, Serafini M.

Br J Haematol. 2017 Nov;179(4):669-673. doi: 10.1111/bjh.14234. Epub 2016 Aug 2. No abstract available.

PMID:
27480905
19.

No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels.

Sacchetti B, Funari A, Remoli C, Giannicola G, Kogler G, Liedtke S, Cossu G, Serafini M, Sampaolesi M, Tagliafico E, Tenedini E, Saggio I, Robey PG, Riminucci M, Bianco P.

Stem Cell Reports. 2016 Jun 14;6(6):897-913. doi: 10.1016/j.stemcr.2016.05.011.

20.

Neonatal cellular and gene therapies for mucopolysaccharidoses: the earlier the better?

Tomatsu S, Azario I, Sawamoto K, Pievani AS, Biondi A, Serafini M.

J Inherit Metab Dis. 2016 Mar;39(2):189-202. doi: 10.1007/s10545-015-9900-2. Epub 2015 Nov 17. Review.

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