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Items: 1 to 20 of 164

1.

Bromodomain and Extraterminal Proteins as Novel Epigenetic Targets for Renal Diseases.

Morgado-Pascual JL, Rayego-Mateos S, Tejedor L, Suarez-Alvarez B, Ruiz-Ortega M.

Front Pharmacol. 2019 Nov 8;10:1315. doi: 10.3389/fphar.2019.01315. eCollection 2019. Review.

2.

Design and optimization strategies for the development of new drugs that treat chronic kidney disease.

Ramos AM, Fernández-Fernández B, Pérez-Gómez MV, Carriazo Julio SM, Sanchez-Niño MD, Sanz A, Ruiz-Ortega M, Ortiz A.

Expert Opin Drug Discov. 2020 Jan;15(1):101-115. doi: 10.1080/17460441.2020.1690450. Epub 2019 Nov 18.

PMID:
31736379
3.

Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes.

Rodriguez RM, Suarez-Alvarez B, Lavín JL, Ascensión AM, Gonzalez M, Lozano JJ, Raneros AB, Bulnes PD, Vidal-Castiñeira JR, Huidobro C, Martin-Martin C, Sanz AB, Ruiz-Ortega M, Puig-Kröger A, Corbí AL, Araúzo-Bravo MJ, Aransay AM, Lopez-Larrea C.

Cell Rep. 2019 Oct 22;29(4):860-872.e5. doi: 10.1016/j.celrep.2019.09.035.

4.

Interleukin 17A Participates in Renal Inflammation Associated to Experimental and Human Hypertension.

Orejudo M, Rodrigues-Diez RR, Rodrigues-Diez R, Garcia-Redondo A, Santos-Sánchez L, Rández-Garbayo J, Cannata-Ortiz P, Ramos AM, Ortiz A, Selgas R, Mezzano S, Lavoz C, Ruiz-Ortega M.

Front Pharmacol. 2019 Sep 13;10:1015. doi: 10.3389/fphar.2019.01015. eCollection 2019.

5.

Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is Required for Organ Regeneration in the Zebrafish.

Sanz-Morejón A, García-Redondo AB, Reuter H, Marques IJ, Bates T, Galardi-Castilla M, Große A, Manig S, Langa X, Ernst A, Piragyte I, Botos MA, González-Rosa JM, Ruiz-Ortega M, Briones AM, Salaices M, Englert C, Mercader N.

Cell Rep. 2019 Jul 30;28(5):1296-1306.e6. doi: 10.1016/j.celrep.2019.06.091.

6.

Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis.

Droguett A, Valderrama G, Burgos ME, Carpio D, Saka C, Egido J, Ruiz-Ortega M, Mezzano S.

Sci Rep. 2019 May 3;9(1):6867. doi: 10.1038/s41598-019-43358-5.

7.

PGC-1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI.

Fontecha-Barriuso M, Martín-Sánchez D, Martinez-Moreno JM, Carrasco S, Ruiz-Andrés O, Monsalve M, Sanchez-Ramos C, Gómez MJ, Ruiz-Ortega M, Sánchez-Niño MD, Cannata-Ortiz P, Cabello R, Gonzalez-Enguita C, Ortiz A, Sanz AB.

J Pathol. 2019 Sep;249(1):65-78. doi: 10.1002/path.5282. Epub 2019 Jun 12.

PMID:
30982966
8.

Interleukin-17A blockade reduces albuminuria and kidney injury in an accelerated model of diabetic nephropathy.

Lavoz C, Matus YS, Orejudo M, Carpio JD, Droguett A, Egido J, Mezzano S, Ruiz-Ortega M.

Kidney Int. 2019 Jun;95(6):1418-1432. doi: 10.1016/j.kint.2018.12.031. Epub 2019 Mar 8.

9.

Inflammatory and Fibrotic Mediators in Renal Diseases.

Rayego-Mateos S, Goldschmeding R, Ruiz-Ortega M.

Mediators Inflamm. 2019 Feb 10;2019:7025251. doi: 10.1155/2019/7025251. eCollection 2019. No abstract available.

10.

Pentoxifylline for Renal Protection in Diabetic Kidney Disease. A Model of Old Drugs for New Horizons.

Donate-Correa J, Tagua VG, Ferri C, Martín-Núñez E, Hernández-Carballo C, Ureña-Torres P, Ruiz-Ortega M, Ortiz A, Mora-Fernández C, Navarro-González JF.

J Clin Med. 2019 Feb 27;8(3). pii: E287. doi: 10.3390/jcm8030287. Review.

11.

Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage.

Rayego-Mateos S, Rodrigues-Diez R, Morgado-Pascual JL, Valentijn F, Valdivielso JM, Goldschmeding R, Ruiz-Ortega M.

Mediators Inflamm. 2018 Dec 23;2018:8739473. doi: 10.1155/2018/8739473. eCollection 2018. Review.

12.

Epigenetic Modification Mechanisms Involved in Inflammation and Fibrosis in Renal Pathology.

Morgado-Pascual JL, Marchant V, Rodrigues-Diez R, Dolade N, Suarez-Alvarez B, Kerr B, Valdivielso JM, Ruiz-Ortega M, Rayego-Mateos S.

Mediators Inflamm. 2018 Dec 13;2018:2931049. doi: 10.1155/2018/2931049. eCollection 2018. Review.

13.

Advances in understanding the role of angiotensin-regulated proteins in kidney diseases.

Sanz AB, Ramos AM, Soler MJ, Sanchez-Niño MD, Fernandez-Fernandez B, Perez-Gomez MV, Ortega MR, Alvarez-Llamas G, Ortiz A.

Expert Rev Proteomics. 2019 Jan;16(1):77-92. doi: 10.1080/14789450.2018.1545577. Epub 2018 Nov 27.

PMID:
30412432
14.

Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis.

Marquez-Exposito L, Lavoz C, Rodrigues-Diez RR, Rayego-Mateos S, Orejudo M, Cantero-Navarro E, Ortiz A, Egido J, Selgas R, Mezzano S, Ruiz-Ortega M.

Front Pharmacol. 2018 Oct 17;9:1195. doi: 10.3389/fphar.2018.01195. eCollection 2018.

15.

Targeting inflammation in diabetic nephropathy: a tale of hope.

Moreno JA, Gomez-Guerrero C, Mas S, Sanz AB, Lorenzo O, Ruiz-Ortega M, Opazo L, Mezzano S, Egido J.

Expert Opin Investig Drugs. 2018 Nov;27(11):917-930. doi: 10.1080/13543784.2018.1538352. Epub 2018 Oct 23. Review.

PMID:
30334635
16.

Branched-chain amino acids promote endothelial dysfunction through increased reactive oxygen species generation and inflammation.

Zhenyukh O, González-Amor M, Rodrigues-Diez RR, Esteban V, Ruiz-Ortega M, Salaices M, Mas S, Briones AM, Egido J.

J Cell Mol Med. 2018 Oct;22(10):4948-4962. doi: 10.1111/jcmm.13759. Epub 2018 Jul 31.

17.

Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression.

Castillo-Rodriguez E, Fernandez-Prado R, Esteras R, Perez-Gomez MV, Gracia-Iguacel C, Fernandez-Fernandez B, Kanbay M, Tejedor A, Lazaro A, Ruiz-Ortega M, Gonzalez-Parra E, Sanz AB, Ortiz A, Sanchez-Niño MD.

Toxins (Basel). 2018 Jul 19;10(7). pii: E300. doi: 10.3390/toxins10070300. Review.

18.

CCL20 blockade increases the severity of nephrotoxic folic acid-induced acute kidney injury.

González-Guerrero C, Morgado-Pascual JL, Cannata-Ortiz P, Ramos-Barron MA, Gómez-Alamillo C, Arias M, Mezzano S, Egido J, Ruiz-Ortega M, Ortiz A, Ramos AM.

J Pathol. 2018 Oct;246(2):191-204. doi: 10.1002/path.5132. Epub 2018 Aug 27.

PMID:
29984403
19.

Gremlin activates the Notch pathway linked to renal inflammation.

Lavoz C, Poveda J, Marquez-Exposito L, Rayego-Mateos S, Rodrigues-Diez RR, Ortiz A, Egido J, Mezzano S, Ruiz-Ortega M.

Clin Sci (Lond). 2018 Jun 5;132(11):1097-1115. doi: 10.1042/CS20171553. Print 2018 Jun 14.

PMID:
29720422
20.

TWEAK and RIPK1 mediate a second wave of cell death during AKI.

Martin-Sanchez D, Fontecha-Barriuso M, Carrasco S, Sanchez-Niño MD, Mässenhausen AV, Linkermann A, Cannata-Ortiz P, Ruiz-Ortega M, Egido J, Ortiz A, Sanz AB.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4182-4187. doi: 10.1073/pnas.1716578115. Epub 2018 Mar 27. Erratum in: Proc Natl Acad Sci U S A. 2018 May 7;:.

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