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Items: 18

1.

Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.

Tesei A, Cortesi M, Pignatta S, Arienti C, Dondio GM, Bigogno C, Malacrida A, Miloso M, Meregalli C, Chiorazzi A, Carozzi V, Cavaletti G, Rui M, Marra A, Rossi D, Collina S.

Front Pharmacol. 2019 May 14;10:490. doi: 10.3389/fphar.2019.00490. eCollection 2019.

2.

Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.

Rui M, Rossino G, Coniglio S, Monteleone S, Scuteri A, Malacrida A, Rossi D, Catenacci L, Sorrenti M, Paolillo M, Curti D, Venturini L, Schepmann D, Wünsch B, Liedl KR, Cavaletti G, Pace V, Urban E, Collina S.

Eur J Med Chem. 2018 Oct 5;158:353-370. doi: 10.1016/j.ejmech.2018.09.010. Epub 2018 Sep 8.

PMID:
30223122
3.

Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead.

Martino E, Casamassima G, Castiglione S, Cellupica E, Pantalone S, Papagni F, Rui M, Siciliano AM, Collina S.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2816-2826. doi: 10.1016/j.bmcl.2018.06.044. Epub 2018 Jun 25. Review.

PMID:
30122223
4.

Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer.

Tesei A, Cortesi M, Zamagni A, Arienti C, Pignatta S, Zanoni M, Paolillo M, Curti D, Rui M, Rossi D, Collina S.

Front Pharmacol. 2018 Jul 10;9:711. doi: 10.3389/fphar.2018.00711. eCollection 2018. Review.

5.

A practical guide for using lithium halocarbenoids in homologation reactions.

Monticelli S, Rui M, Castoldi L, Missere G, Pace V.

Monatsh Chem. 2018;149(7):1285-1291. doi: 10.1007/s00706-018-2232-9. Epub 2018 Jun 11.

6.

PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds.

Rossino G, Raimondi MV, Rui M, Di Giacomo M, Rossi D, Collina S.

Molecules. 2018 Mar 28;23(4). pii: E775. doi: 10.3390/molecules23040775.

7.

Regulation of Aquaporin Functional Properties Mediated by the Antioxidant Effects of Natural Compounds.

Pellavio G, Rui M, Caliogna L, Martino E, Gastaldi G, Collina S, Laforenza U.

Int J Mol Sci. 2017 Dec 8;18(12). pii: E2665. doi: 10.3390/ijms18122665.

8.

Marrubium vulgare L. Leave Extract: Phytochemical Composition, Antioxidant and Wound Healing Properties.

Amri B, Martino E, Vitulo F, Corana F, Kaâb LB, Rui M, Rossi D, Mori M, Rossi S, Collina S.

Molecules. 2017 Oct 28;22(11). pii: E1851. doi: 10.3390/molecules22111851.

9.

Are sigma receptor modulators a weapon against multiple sclerosis disease?

Collina S, Rui M, Stotani S, Bignardi E, Rossi D, Curti D, Giordanetto F, Malacrida A, Scuteri A, Cavaletti G.

Future Med Chem. 2017 Nov;9(17):2029-2051. doi: 10.4155/fmc-2017-0122. Epub 2017 Oct 27.

PMID:
29076758
10.

Approaches for multi-gram scale isolation of enantiomers for drug discovery.

Rossi D, Tarantino M, Rossino G, Rui M, Juza M, Collina S.

Expert Opin Drug Discov. 2017 Dec;12(12):1253-1269. doi: 10.1080/17460441.2017.1383981. Epub 2017 Oct 3. Review.

PMID:
28971706
11.

Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones.

Pace V, Castoldi L, Mazzeo E, Rui M, Langer T, Holzer W.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12677-12682. doi: 10.1002/anie.201706236. Epub 2017 Sep 1.

PMID:
28722252
12.

PKC in Regenerative Therapy: New Insights for Old Targets.

Rui M, Nasti R, Bignardi E, Della Volpe S, Rossino G, Rossi D, Collina S.

Pharmaceuticals (Basel). 2017 May 18;10(2). pii: E46. doi: 10.3390/ph10020046. Review.

13.

Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016).

Collina S, Bignardi E, Rui M, Rossi D, Gaggeri R, Zamagni A, Cortesi M, Tesei A.

Expert Opin Ther Pat. 2017 May;27(5):565-578. doi: 10.1080/13543776.2017.1276569. Epub 2017 Jan 13. Review.

PMID:
28051882
14.

Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines.

Rossi D, Rui M, Di Giacomo M, Schepmann D, Wünsch B, Monteleone S, Liedl KR, Collina S.

Bioorg Med Chem. 2017 Jan 1;25(1):11-19. doi: 10.1016/j.bmc.2016.10.005. Epub 2016 Oct 11.

PMID:
27838169
15.

The Use of the Comins-Meyers Amide in Synthetic Chemistry: an Overview.

Monticelli S, Parisi G, Rui M, de la Vega-Hernández K, Murgia I, Senatore R, Holzer W, Urban E, Langer T, Pace V.

Nat Prod Commun. 2016 Nov;11(11):1729-1732.

PMID:
30475518
16.

Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents.

Rui M, Rossi D, Marra A, Paolillo M, Schinelli S, Curti D, Tesei A, Cortesi M, Zamagni A, Laurini E, Pricl S, Schepmann D, Wűnsch B, Urban E, Pace V, Collina S.

Eur J Med Chem. 2016 Nov 29;124:649-665. doi: 10.1016/j.ejmech.2016.08.067. Epub 2016 Aug 31.

PMID:
27614411
17.

Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment.

Rui M, Marra A, Pace V, Juza M, Rossi D, Collina S.

Molecules. 2016 Sep 10;21(9). pii: E1210. doi: 10.3390/molecules21091210.

18.

"Fit-for-purpose" development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel σ1 receptor agonist.

Rossi D, Marra A, Rui M, Brambilla S, Juza M, Collina S.

J Pharm Biomed Anal. 2016 Jan 25;118:363-369. doi: 10.1016/j.jpba.2015.10.047. Epub 2015 Nov 4.

PMID:
26600118

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