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Items: 1 to 20 of 23


Excessive Accumulation of Ca2 + in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State.

Canato M, Capitanio P, Cancellara L, Leanza L, Raffaello A, Reane DV, Marcucci L, Michelucci A, Protasi F, Reggiani C.

Front Physiol. 2019 Sep 13;10:1142. doi: 10.3389/fphys.2019.01142. eCollection 2019.


DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass.

Favaro G, Romanello V, Varanita T, Andrea Desbats M, Morbidoni V, Tezze C, Albiero M, Canato M, Gherardi G, De Stefani D, Mammucari C, Blaauw B, Boncompagni S, Protasi F, Reggiani C, Scorrano L, Salviati L, Sandri M.

Nat Commun. 2019 Jun 12;10(1):2576. doi: 10.1038/s41467-019-10226-9.


A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss.

Pozzer D, Varone E, Chernorudskiy A, Schiarea S, Missiroli S, Giorgi C, Pinton P, Canato M, Germinario E, Nogara L, Blaauw B, Zito E.

Redox Biol. 2019 Jan;20:354-366. doi: 10.1016/j.redox.2018.10.017. Epub 2018 Oct 26.


A 3D diffusional-compartmental model of the calcium dynamics in cytosol, sarcoplasmic reticulum and mitochondria of murine skeletal muscle fibers.

Marcucci L, Canato M, Protasi F, Stienen GJM, Reggiani C.

PLoS One. 2018 Jul 26;13(7):e0201050. doi: 10.1371/journal.pone.0201050. eCollection 2018.


Resveratrol treatment reduces the appearance of tubular aggregates and improves the resistance to fatigue in aging mice skeletal muscles.

Toniolo L, Fusco P, Formoso L, Mazzi A, Canato M, Reggiani C, Giacomello E.

Exp Gerontol. 2018 Oct 1;111:170-179. doi: 10.1016/j.exger.2018.07.012. Epub 2018 Jul 20.


Estrogens Protect Calsequestrin-1 Knockout Mice from Lethal Hyperthermic Episodes by Reducing Oxidative Stress in Muscle.

Michelucci A, Boncompagni S, Canato M, Reggiani C, Protasi F.

Oxid Med Cell Longev. 2017;2017:6936897. doi: 10.1155/2017/6936897. Epub 2017 Sep 10.


Strenuous exercise triggers a life-threatening response in mice susceptible to malignant hyperthermia.

Michelucci A, Paolini C, Boncompagni S, Canato M, Reggiani C, Protasi F.

FASEB J. 2017 Aug;31(8):3649-3662. doi: 10.1096/fj.201601292R. Epub 2017 May 2.


Protein Supplementation Does Not Further Increase Latissimus Dorsi Muscle Fiber Hypertrophy after Eight Weeks of Resistance Training in Novice Subjects, but Partially Counteracts the Fast-to-Slow Muscle Fiber Transition.

Paoli A, Pacelli QF, Cancellara P, Toniolo L, Moro T, Canato M, Miotti D, Neri M, Morra A, Quadrelli M, Reggiani C.

Nutrients. 2016 Jun 1;8(6). pii: E331. doi: 10.3390/nu8060331.


Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death.

Michelucci A, Paolini C, Canato M, Wei-Lapierre L, Pietrangelo L, De Marco A, Reggiani C, Dirksen RT, Protasi F.

Anesthesiology. 2015 Sep;123(3):603-17. doi: 10.1097/ALN.0000000000000748.


The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models?

Canato M, Capitanio P, Reggiani C, Cancellara L.

J Muscle Res Cell Motil. 2015 Feb;36(1):61-9. doi: 10.1007/s10974-014-9396-7. Epub 2014 Nov 26. Review.


Protein supplementation increases postexercise plasma myostatin concentration after 8 weeks of resistance training in young physically active subjects.

Paoli A, Pacelli QF, Neri M, Toniolo L, Cancellara P, Canato M, Moro T, Quadrelli M, Morra A, Faggian D, Plebani M, Bianco A, Reggiani C.

J Med Food. 2015 Jan;18(1):137-43. doi: 10.1089/jmf.2014.0004.


Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.

Scorzeto M, Giacomello M, Toniolo L, Canato M, Blaauw B, Paolini C, Protasi F, Reggiani C, Stienen GJ.

PLoS One. 2013 Oct 3;8(10):e74919. doi: 10.1371/journal.pone.0074919. eCollection 2013.


Myosin isoforms and contractile properties of single fibers of human Latissimus Dorsi muscle.

Paoli A, Pacelli QF, Cancellara P, Toniolo L, Moro T, Canato M, Miotti D, Reggiani C.

Biomed Res Int. 2013;2013:249398. doi: 10.1155/2013/249398. Epub 2013 Jul 22.


Inflammation in muscular dystrophy and the beneficial effects of non-steroidal anti-inflammatory drugs.

Serra F, Quarta M, Canato M, Toniolo L, De Arcangelis V, Trotta A, Spath L, Monaco L, Reggiani C, Naro F.

Muscle Nerve. 2012 Nov;46(5):773-84. doi: 10.1002/mus.23432. Epub 2012 Jul 27.


Lessons from calsequestrin-1 ablation in vivo: much more than a Ca(2+) buffer after all.

Protasi F, Paolini C, Canato M, Reggiani C, Quarta M.

J Muscle Res Cell Motil. 2011 Dec;32(4-5):257-70. doi: 10.1007/s10974-011-9277-2. Epub 2011 Dec 1.


Calsequestrin (CASQ1) rescues function and structure of calcium release units in skeletal muscles of CASQ1-null mice.

Tomasi M, Canato M, Paolini C, Dainese M, Reggiani C, Volpe P, Protasi F, Nori A.

Am J Physiol Cell Physiol. 2012 Feb 1;302(3):C575-86. doi: 10.1152/ajpcell.00119.2011. Epub 2011 Nov 2.


The modulation of myogenic cells differentiation using a semiconductor-muscle junction.

Quarta M, Scorzeto M, Canato M, Dal Maschio M, Conte D, Blaauw B, Vassanelli S, Reggiani C.

Biomaterials. 2011 Jun;32(18):4228-37. doi: 10.1016/j.biomaterials.2011.02.024. Epub 2011 Mar 23.


Eccentric contractions lead to myofibrillar dysfunction in muscular dystrophy.

Blaauw B, Agatea L, Toniolo L, Canato M, Quarta M, Dyar KA, Danieli-Betto D, Betto R, Schiaffino S, Reggiani C.

J Appl Physiol (1985). 2010 Jan;108(1):105-11. doi: 10.1152/japplphysiol.00803.2009. Epub 2009 Nov 12.


Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation.

Blaauw B, Canato M, Agatea L, Toniolo L, Mammucari C, Masiero E, Abraham R, Sandri M, Schiaffino S, Reggiani C.

FASEB J. 2009 Nov;23(11):3896-905. doi: 10.1096/fj.09-131870. Epub 2009 Aug 6.


Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice.

Dainese M, Quarta M, Lyfenko AD, Paolini C, Canato M, Reggiani C, Dirksen RT, Protasi F.

FASEB J. 2009 Jun;23(6):1710-20. doi: 10.1096/fj.08-121335. Epub 2009 Feb 23.

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