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Items: 1 to 20 of 39

1.

Diterpenoids of terrestrial origin.

Hanson JR, Nichols T, Mukhrish Y, Bagley MC.

Nat Prod Rep. 2019 Nov 13;36(11):1499-1512. doi: 10.1039/c8np00079d. Review.

PMID:
31417997
2.

Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor.

Bannister ML, Alvarez-Laviada A, Thomas NL, Mason SA, Coleman S, du Plessis CL, Moran AT, Neill-Hall D, Osman H, Bagley MC, MacLeod KT, George CH, Williams AJ.

Br J Pharmacol. 2016 Aug;173(15):2446-59. doi: 10.1111/bph.13521. Epub 2016 Jun 29.

3.

Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts.

Davis T, Brook AJ, Rokicki MJ, Bagley MC, Kipling D.

Pharmaceuticals (Basel). 2016 Apr 28;9(2). pii: E23. doi: 10.3390/ph9020023.

4.

The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells.

Bagley MC, Dwyer JE, Baashen M, Dix MC, Murziani PG, Rokicki MJ, Kipling D, Davis T.

Org Biomol Chem. 2016 Jan 21;14(3):947-56. doi: 10.1039/c5ob02229k. Epub 2015 Nov 27.

PMID:
26611938
5.

Microwave-Assisted Synthesis of a MK2 Inhibitor by Suzuki-Miyaura Coupling for Study in Werner Syndrome Cells.

Bagley MC, Baashen M, Chuckowree I, Dwyer JE, Kipling D, Davis T.

Pharmaceuticals (Basel). 2015 Jun 3;8(2):257-76. doi: 10.3390/ph8020257.

6.

Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors.

Bagley MC, Dwyer JE, Molina MD, Rand AW, Rand HL, Tomkinson NC.

Org Biomol Chem. 2015 Jun 28;13(24):6814-24. doi: 10.1039/c5ob00819k.

7.

One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor.

Bagley MC, Fusillo V, Jenkins RL, Lubinu MC, Mason C.

Beilstein J Org Chem. 2013 Sep 30;9:1957-68. doi: 10.3762/bjoc.9.232. eCollection 2013.

8.

Small molecule inhibition of p38 MAP kinase extends the replicative life span of human ATR-Seckel syndrome fibroblasts.

Tivey HS, Rokicki MJ, Barnacle JR, Rogers MJ, Bagley MC, Kipling D, Davis T.

J Gerontol A Biol Sci Med Sci. 2013 Sep;68(9):1001-9. doi: 10.1093/gerona/gls336. Epub 2013 Feb 11.

9.

The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome.

Davis T, Rokicki MJ, Bagley MC, Kipling D.

Chem Cent J. 2013 Jan 29;7(1):18. doi: 10.1186/1752-153X-7-18.

10.

Microwave-assisted synthesis and antioxidant properties of hydrazinyl thiazolyl coumarin derivatives.

Osman H, Arshad A, Lam CK, Bagley MC.

Chem Cent J. 2012 Apr 17;6(1):32. doi: 10.1186/1752-153X-6-32.

11.

Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors.

Davis T, Dix MC, Rokicki MJ, Brook AJ, Widdowson CS, Kipling D, Bagley MC.

Chem Cent J. 2011 Dec 8;5(1):83. doi: 10.1186/1752-153X-5-83.

12.

Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives.

Arshad A, Osman H, Bagley MC, Lam CK, Mohamad S, Zahariluddin AS.

Eur J Med Chem. 2011 Sep;46(9):3788-94. doi: 10.1016/j.ejmech.2011.05.044. Epub 2011 Jun 7.

PMID:
21712145
13.

Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells.

Bagley MC, Davis T, Dix MC, Murziani PG, Rokicki MJ, Kipling D.

Future Med Chem. 2010 Feb;2(2):203-13. doi: 10.4155/fmc.09.160.

PMID:
21426187
14.

Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome.

Bagley MC, Davis T, Rokicki MJ, Widdowson CS, Kipling D.

Future Med Chem. 2010 Feb;2(2):193-201. doi: 10.4155/fmc.09.163. Erratum in: Future Med Chem. 2011 Jan;3(1):138.

PMID:
21426186
15.

Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome.

Bagley MC, Davis T, Dix MC, Fusillo V, Pigeaux M, Rokicki MJ, Kipling D.

Future Med Chem. 2010 Sep;2(9):1417-27. doi: 10.4155/fmc.10.217.

PMID:
21426137
16.

Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide.

Bagley MC, Glover C.

Molecules. 2010 Apr 30;15(5):3211-27. doi: 10.3390/molecules15053211.

17.

Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts.

Davis T, Bachler MA, Wyllie FS, Bagley MC, Kipling D.

Ann N Y Acad Sci. 2010 Jun;1197:45-8. doi: 10.1111/j.1749-6632.2010.05195.x. Review.

PMID:
20536832
18.

Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome.

Bagley MC, Davis T, Murziani PG, Widdowson CS, Kipling D.

Pharmaceuticals (Basel). 2010 Jun 4;3(6):1842-1872. Review.

19.

Microwave-assisted synthesis and complexation of luminescent cyanobipyridyl-zinc(II) bis(thiolate) complexes with intrinsic and ancillary photophysical tunability.

Bagley MC, Lin Z, Pope SJ.

Dalton Trans. 2010 Apr 7;39(13):3163-6. doi: 10.1039/c001898h. Epub 2010 Feb 12.

PMID:
20449441
20.

Rapid synthesis of 3-cyanopyridine-derived chromophores with two-dimensional tunability and solvatochromic photophysical properties.

Bagley MC, Lin Z, Pope SJ.

Chem Commun (Camb). 2009 Sep 14;(34):5165-7. doi: 10.1039/b910664b. Epub 2009 Jul 16.

PMID:
20448981

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