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Items: 1 to 20 of 142


Anticancer potential of naturally occurring immunoepigenetic modulators: A promising avenue?

Schnekenburger M, Dicato M, Diederich MF.

Cancer. 2019 May 15;125(10):1612-1628. doi: 10.1002/cncr.32041. Epub 2019 Mar 6. Review.


Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis.

Florean C, Song S, Dicato M, Diederich M.

Free Radic Biol Med. 2019 Apr;134:177-189. doi: 10.1016/j.freeradbiomed.2019.01.008. Epub 2019 Jan 10. Review.


Natural modulators of the hallmarks of immunogenic cell death.

Radogna F, Dicato M, Diederich M.

Biochem Pharmacol. 2019 Apr;162:55-70. doi: 10.1016/j.bcp.2018.12.016. Epub 2019 Jan 5. Review.


Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(R), 6(S), 1'(R), 6'(S), 11(R), 17(S)-Fistularin-3 and Bcl-2 Inhibitor Venetoclax.

Florean C, Kim KR, Schnekenburger M, Kim HJ, Moriou C, Debitus C, Dicato M, Al-Mourabit A, Han BW, Diederich M.

Mar Drugs. 2018 Dec 19;16(12). pii: E518. doi: 10.3390/md16120518.


Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells.

Orsini M, Chateauvieux S, Rhim J, Gaigneaux A, Cheillan D, Christov C, Dicato M, Morceau F, Diederich M.

Cell Death Differ. 2018 Dec 13. doi: 10.1038/s41418-018-0245-x. [Epub ahead of print]


Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release.

Mazumder A, Lee JY, Talhi O, Cerella C, Chateauvieux S, Gaigneaux A, Hong CR, Kang HJ, Lee Y, Kim KW, Kim DW, Shin HY, Dicato M, Bachari K, Silva AMS, Orlikova-Boyer B, Diederich M.

Cancer Lett. 2018 Dec 1;438:197-218. doi: 10.1016/j.canlet.2018.07.041. Epub 2018 Sep 8.


Autophagy as a pharmacological target in hematopoiesis and hematological disorders.

Orsini M, Morceau F, Dicato M, Diederich M.

Biochem Pharmacol. 2018 Jun;152:347-361. doi: 10.1016/j.bcp.2018.04.007. Epub 2018 Apr 13. Review.


Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.

Schneider NFZ, Cerella C, Lee JY, Mazumder A, Kim KR, de Carvalho A, Munkert J, Pádua RM, Kreis W, Kim KW, Christov C, Dicato M, Kim HJ, Han BW, Braga FC, Simões CMO, Diederich M.

Front Pharmacol. 2018 Mar 1;9:70. doi: 10.3389/fphar.2018.00070. eCollection 2018.


The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition.

Schnekenburger M, Mathieu V, Lefranc F, Jang JY, Masi M, Kijjoa A, Evidente A, Kim HJ, Kiss R, Dicato M, Han BW, Diederich M.

Molecules. 2018 Feb 5;23(2). pii: E333. doi: 10.3390/molecules23020333.


Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer.

Lee JY, Talhi O, Jang D, Cerella C, Gaigneaux A, Kim KW, Lee JW, Dicato M, Bachari K, Han BW, Silva AMS, Orlikova B, Diederich M.

Cancer Lett. 2018 Mar 1;416:94-108. doi: 10.1016/j.canlet.2017.12.007. Epub 2017 Dec 13.


The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.

Ji S, Lee JY, Schrör J, Mazumder A, Jang DM, Chateauvieux S, Schnekenburger M, Hong CR, Christov C, Kang HJ, Lee Y, Han BW, Kim KW, Shin HY, Dicato M, Cerella C, König GM, Orlikova B, Diederich M.

Cancer Lett. 2018 Mar 1;416:109-123. doi: 10.1016/j.canlet.2017.12.011. Epub 2017 Dec 13.


Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways.

Lernoux M, Schnekenburger M, Dicato M, Diederich M.

Pharmacol Res. 2018 Mar;129:337-356. doi: 10.1016/j.phrs.2017.11.004. Epub 2017 Nov 11. Review.


Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.

Yagdi Efe E, Mazumder A, Lee JY, Gaigneaux A, Radogna F, Nasim MJ, Christov C, Jacob C, Kim KW, Dicato M, Chaimbault P, Cerella C, Diederich M.

Cancer Lett. 2017 Dec 1;410:139-157. doi: 10.1016/j.canlet.2017.09.011. Epub 2017 Sep 21.


Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

Schnekenburger M, Goffin E, Lee JY, Jang JY, Mazumder A, Ji S, Rogister B, Bouider N, Lefranc F, Miklos W, Mathieu V, de Tullio P, Kim KW, Dicato M, Berger W, Han BW, Kiss R, Pirotte B, Diederich M.

J Med Chem. 2017 Jun 8;60(11):4714-4733. doi: 10.1021/acs.jmedchem.7b00533. Epub 2017 May 25.


Safety and efficacy of biosimilars in oncology.

Schellekens H, Smolen JS, Dicato M, Rifkin RM.

Lancet Oncol. 2016 Nov;17(11):e502-e509. doi: 10.1016/S1470-2045(16)30374-6. Review. Erratum in: Lancet Oncol. 2017 Mar;18(3):e134.


Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

Yagdi E, Cerella C, Dicato M, Diederich M.

Food Chem Toxicol. 2016 Sep;95:219-33. doi: 10.1016/j.fct.2016.07.016. Epub 2016 Jul 16. Review.


Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.

Florean C, Schnekenburger M, Lee JY, Kim KR, Mazumder A, Song S, Kim JM, Grandjenette C, Kim JG, Yoon AY, Dicato M, Kim KW, Christov C, Han BW, Proksch P, Diederich M.

Oncotarget. 2016 Apr 26;7(17):24027-49. doi: 10.18632/oncotarget.8210.


Anticipatory Nausea, Risk Factors, and Its Impact on Chemotherapy-Induced Nausea and Vomiting: Results From the Pan European Emesis Registry Study.

Molassiotis A, Lee PH, Burke TA, Dicato M, Gascon P, Roila F, Aapro M.

J Pain Symptom Manage. 2016 Jun;51(6):987-93. doi: 10.1016/j.jpainsymman.2015.12.317. Epub 2016 Feb 16.


Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3',4',5'-Pentamethoxyflavone Isolated from Lantana ukambensis.

Sawadogo WR, Cerella C, Al-Mourabit A, Moriou C, Teiten MH, Guissou IP, Dicato M, Diederich M.

Nutrients. 2015 Dec 10;7(12):10388-97. doi: 10.3390/nu7125537.

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