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Items: 1 to 20 of 29


UHPLC-Q/Orbitrap/MS/MS Fingerprinting, Free Radical Scavenging, and Antimicrobial Activity of Tessaria absinthiodes (Hook. & Arn.) DC. (Asteraceae) Lyophilized Decoction from Argentina and Chile.

Gómez J, Simirgiotis MJ, Lima B, Gamarra-Luques C, Bórquez J, Caballero D, Feresin GE, Tapia A.

Antioxidants (Basel). 2019 Nov 28;8(12). pii: E593. doi: 10.3390/antiox8120593.


Polyphenolic Composition and Hypotensive Effects of Parastrephia quadrangularis (Meyen) Cabrera in Rat.

Cifuentes F, Palacios J, R Nwokocha C, Bórquez J, Simirgiotis MJ, Norambuena I, Chiong M, Paredes A.

Antioxidants (Basel). 2019 Nov 27;8(12). pii: E591. doi: 10.3390/antiox8120591.


Biological activity and chemical characterization of Pouteria lucuma seeds: A possible use of an agricultural waste.

Guerrero-Castillo P, Reyes S, Robles J, Simirgiotis MJ, Sepulveda B, Fernandez-Burgos R, Areche C.

Waste Manag. 2019 Apr 1;88:319-327. doi: 10.1016/j.wasman.2019.03.055. Epub 2019 Mar 30.


Antioxidant, Gastroprotective, Cytotoxic Activities and UHPLC PDA-Q Orbitrap Mass Spectrometry Identification of Metabolites in Baccharis grisebachii Decoction.

Gómez J, Simirgiotis MJ, Lima B, Paredes JD, Villegas Gabutti CM, Gamarra-Luques C, Bórquez J, Luna L, Wendel GH, Maria AO, Feresin GE, Tapia A.

Molecules. 2019 Mar 19;24(6). pii: E1085. doi: 10.3390/molecules24061085.


Gastroprotective Activity of Parastrephia quadrangularis (Meyen), Cabrera from the Atacama Desert.

Ardiles A, Barrientos R, Simirgiotis MJ, Bórquez J, Sepúlveda B, Areche C.

Molecules. 2018 Sep 15;23(9). pii: E2361. doi: 10.3390/molecules23092361.


UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC. - Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties.

Jiménez-González A, Quispe C, Bórquez J, Sepúlveda B, Riveros F, Areche C, Nagles E, García-Beltrán O, Simirgiotis MJ.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):936-944. doi: 10.1080/14756366.2018.1466880.


UHPLC-MS Metabolome Fingerprinting: The Isolation of Main Compounds and Antioxidant Activity of the Andean Species Tetraglochin ameghinoi (Speg.) Speg.

Luna L, Simirgiotis MJ, Lima B, Bórquez J, Feresin GE, Tapia A.

Molecules. 2018 Mar 29;23(4). pii: E793. doi: 10.3390/molecules23040793.


High resolution UHPLC-MS characterization and isolation of main compounds from the antioxidant medicinal plant Parastrephia lucida (Meyen).

Echiburu-Chau C, Pastén L, Parra C, Bórquez J, Mocan A, Simirgiotis MJ.

Saudi Pharm J. 2017 Nov;25(7):1032-1039. doi: 10.1016/j.jsps.2017.03.001. Epub 2017 Mar 14.


Metabolomic Analysis of Two Parmotrema Lichens: P. robustum (Degel.) Hale and P. andinum (Mull. Arg.) Hale Using UHPLC-ESI-OT-MS-MS.

Torres-Benítez A, Rivera-Montalvo M, Sepúlveda B, Castro ON, Nagles E, Simirgiotis MJ, García-Beltrán O, Areche C.

Molecules. 2017 Oct 30;22(11). pii: E1861. doi: 10.3390/molecules22111861.


High Resolution UHPLC-MS Metabolomics and Sedative-Anxiolytic Effects of Latua pubiflora: A Mystic Plant used by Mapuche Amerindians.

Sánchez-Montoya EL, Reyes MA, Pardo J, Nuñez-Alarcón J, Ortiz JG, Jorge JC, Bórquez J, Mocan A, Simirgiotis MJ.

Front Pharmacol. 2017 Jul 26;8:494. doi: 10.3389/fphar.2017.00494. eCollection 2017.


Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects.

Nwokocha C, Palacios J, Simirgiotis MJ, Thomas J, Nwokocha M, Young L, Thompson R, Cifuentes F, Paredes A, Delgoda R.

J Ethnopharmacol. 2017 May 5;203:163-170. doi: 10.1016/j.jep.2017.03.037. Epub 2017 Mar 22.


Phenolic Compounds in Chilean Mistletoe (Quintral, Tristerix tetrandus) Analyzed by UHPLC-Q/Orbitrap/MS/MS and Its Antioxidant Properties.

Simirgiotis MJ, Quispe C, Areche C, Sepúlveda B.

Molecules. 2016 Feb 23;21(3):245. doi: 10.3390/molecules21030245.


Isolation of cytotoxic diterpenoids from the Chilean medicinal plant Azorella compacta Phil from the Atacama Desert by high-speed counter-current chromatography.

Bórquez J, Bartolucci NL, Echiburú-Chau C, Winterhalter P, Vallejos J, Jerz G, Simirgiotis MJ.

J Sci Food Agric. 2016 Jun;96(8):2832-8. doi: 10.1002/jsfa.7451. Epub 2015 Oct 1.


Antioxidant Capacities and Analysis of Phenolic Compounds in Three Endemic Nolana Species by HPLC-PDA-ESI-MS.

Simirgiotis MJ, Benites J, Areche C, Sepúlveda B.

Molecules. 2015 Jun 22;20(6):11490-507. doi: 10.3390/molecules200611490.


Seco-taondiol, an unusual meroterpenoid from the Chilean seaweed Stypopodium flabelliforme and its gastroprotective effect in mouse model.

Areche C, Benites J, Cornejo A, Ruiz LM, García-Beltrán O, Simirgiotis MJ, Sepúlveda B.

Mar Drugs. 2015 Mar 30;13(4):1726-38. doi: 10.3390/md13041726.


Anthocyanins and antioxidant capacities of six Chilean berries by HPLC-HR-ESI-ToF-MS.

Ramirez JE, Zambrano R, Sepúlveda B, Kennelly EJ, Simirgiotis MJ.

Food Chem. 2015 Jun 1;176:106-14. doi: 10.1016/j.foodchem.2014.12.039. Epub 2014 Dec 18.


Concise and straightforward asymmetric synthesis of a cyclic natural hydroxy-amino acid.

Simirgiotis MJ, Vallejos J, Areche C, Sepúlveda B.

Molecules. 2014 Nov 26;19(12):19516-31. doi: 10.3390/molecules191219516.


HPLC-UV-MS profiles of phenolic compounds and antioxidant activity of fruits from three citrus species consumed in Northern Chile.

Brito A, Ramirez JE, Areche C, Sepúlveda B, Simirgiotis MJ.

Molecules. 2014 Oct 29;19(11):17400-21. doi: 10.3390/molecules191117400.


A new mulinane diterpenoid from the cushion shrub Azorella compacta growing in Perú.

Salgado F, Areche C, Sepúlveda B, Simirgiotis MJ, Cáceres F, Quispe C, Quispe L, Cano T.

Pharmacogn Mag. 2014 Aug;10(Suppl 3):S543-8. doi: 10.4103/0973-1296.139807.

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