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Items: 19

1.

Decreases in Circulating Concentrations of Long-Chain Acylcarnitines and Free Fatty Acids During the Glucose Tolerance Test Represent Tissue-Specific Insulin Sensitivity.

Makarova E, Makrecka-Kuka M, Vilks K, Volska K, Sevostjanovs E, Grinberga S, Zarkova-Malkova O, Dambrova M, Liepinsh E.

Front Endocrinol (Lausanne). 2019 Dec 17;10:870. doi: 10.3389/fendo.2019.00870. eCollection 2019.

2.

Altered mitochondrial metabolism in the insulin-resistant heart.

Makrecka-Kuka M, Liepinsh E, Murray AJ, Lemieux H, Dambrova M, Tepp K, Puurand M, Käämbre T, Han WH, de Goede P, O'Brien KA, Turan B, Tuncay E, Olgar Y, Rolo AP, Palmeira CM, Boardman NT, Wüst RCI, Larsen TS.

Acta Physiol (Oxf). 2019 Dec 16:e13430. doi: 10.1111/apha.13430. [Epub ahead of print] Review.

PMID:
31840389
3.

Investigation of Antibacterial and Antiinflammatory Activities of Proanthocyanidins from Pelargonium sidoides DC Root Extract.

Jekabsone A, Sile I, Cochis A, Makrecka-Kuka M, Laucaityte G, Makarova E, Rimondini L, Bernotiene R, Raudone L, Vedlugaite E, Baniene R, Smalinskiene A, Savickiene N, Dambrova M.

Nutrients. 2019 Nov 19;11(11). pii: E2829. doi: 10.3390/nu11112829.

4.

Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury.

Perry JB, Davis GN, Allen ME, Makrecka-Kuka M, Dambrova M, Grange RW, Shaikh SR, Brown DA.

J Mol Cell Cardiol. 2019 Oct;135:160-171. doi: 10.1016/j.yjmcc.2019.08.010. Epub 2019 Aug 22.

PMID:
31445917
5.

Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia.

Makrecka-Kuka M, Korzh S, Vilks K, Vilskersts R, Cirule H, Dambrova M, Liepinsh E.

Shock. 2019 Dec;52(6):e153-e162. doi: 10.1097/SHK.0000000000001315.

PMID:
30640252
6.

Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues.

Makrecka-Kuka M, Sevostjanovs E, Vilks K, Volska K, Antone U, Kuka J, Makarova E, Pugovics O, Dambrova M, Liepinsh E.

Sci Rep. 2017 Dec 13;7(1):17528. doi: 10.1038/s41598-017-17797-x.

7.

Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice.

Liepinsh E, Makrecka-Kuka M, Makarova E, Volska K, Vilks K, Sevostjanovs E, Antone U, Kuka J, Vilskersts R, Lola D, Loza E, Grinberga S, Dambrova M.

Biofactors. 2017 Sep 10;43(5):718-730. doi: 10.1002/biof.1378. Epub 2017 Jul 31.

PMID:
28759135
8.

S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity.

Zvejniece L, Svalbe B, Vavers E, Makrecka-Kuka M, Makarova E, Liepins V, Kalvinsh I, Liepinsh E, Dambrova M.

Pharmacol Biochem Behav. 2017 Sep;160:21-29. doi: 10.1016/j.pbb.2017.07.009. Epub 2017 Jul 22.

PMID:
28743458
9.

Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB.

Kuka J, Makrecka-Kuka M, Cirule H, Grinberga S, Sevostjanovs E, Dambrova M, Liepinsh E.

Basic Clin Pharmacol Toxicol. 2017 Aug;121(2):106-112. doi: 10.1111/bcpt.12775. Epub 2017 May 3.

10.

Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria.

Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M.

Toxicol Lett. 2017 Feb 5;267:32-38. doi: 10.1016/j.toxlet.2016.12.017. Epub 2016 Dec 31.

PMID:
28049038
11.

Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria.

Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M.

Biochem J. 2016 May 1;473(9):1191-202. doi: 10.1042/BCJ20160164. Epub 2016 Mar 2.

PMID:
26936967
12.

Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity.

Dambrova M, Makrecka-Kuka M, Vilskersts R, Makarova E, Kuka J, Liepinsh E.

Pharmacol Res. 2016 Nov;113(Pt B):771-780. doi: 10.1016/j.phrs.2016.01.019. Epub 2016 Feb 2. Review.

PMID:
26850121
13.

Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance.

Liepinsh E, Makrecka-Kuka M, Makarova E, Volska K, Svalbe B, Sevostjanovs E, Grinberga S, Kuka J, Dambrova M.

Pharmacol Res. 2016 Nov;113(Pt B):788-795. doi: 10.1016/j.phrs.2015.11.014. Epub 2015 Nov 24.

PMID:
26621248
14.

Structure and Function of CutC Choline Lyase from Human Microbiota Bacterium Klebsiella pneumoniae.

Kalnins G, Kuka J, Grinberga S, Makrecka-Kuka M, Liepinsh E, Dambrova M, Tars K.

J Biol Chem. 2015 Aug 28;290(35):21732-40. doi: 10.1074/jbc.M115.670471. Epub 2015 Jul 17.

15.
16.

Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis.

Vilskersts R, Kuka J, Liepinsh E, Makrecka-Kuka M, Volska K, Makarova E, Sevostjanovs E, Cirule H, Grinberga S, Dambrova M.

Vascul Pharmacol. 2015 Sep;72:101-7. doi: 10.1016/j.vph.2015.05.005. Epub 2015 May 16.

PMID:
25989106
17.

Iodine deficiency during pregnancy: a national cross-sectional survey in Latvia.

Konrade I, Kalere I, Strele I, Makrecka-Kuka M, Jekabsone A, Tetere E, Veisa V, Gavars D, Rezeberga D, Pīrāgs V, Lejnieks A, Dambrova M.

Public Health Nutr. 2015 Nov;18(16):2990-7. doi: 10.1017/S1368980015000464. Epub 2015 Mar 3.

PMID:
25731595
18.

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.

Kuka J, Liepinsh E, Makrecka-Kuka M, Liepins J, Cirule H, Gustina D, Loza E, Zharkova-Malkova O, Grinberga S, Pugovics O, Dambrova M.

Life Sci. 2014 Nov 11;117(2):84-92. doi: 10.1016/j.lfs.2014.09.028. Epub 2014 Oct 7.

PMID:
25301199
19.

Expression and purification of active, stabilized trimethyllysine hydroxylase.

Kazaks A, Makrecka-Kuka M, Kuka J, Voronkova T, Akopjana I, Grinberga S, Pugovics O, Tars K.

Protein Expr Purif. 2014 Dec;104:1-6. doi: 10.1016/j.pep.2014.09.002. Epub 2014 Sep 16.

PMID:
25220864

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