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Items: 13


Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists.

Szűcs E, Stefanucci A, Dimmito MP, Zádor F, Pieretti S, Zengin G, Vécsei L, Benyhe S, Nalli M, Mollica A.

Biomolecules. 2020 Feb 12;10(2). pii: E284. doi: 10.3390/biom10020284.


Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.

Stefanucci A, Dimmito MP, Macedonio G, Ciarlo L, Pieretti S, Novellino E, Lei W, Barlow D, Houseknecht KL, Streicher JM, Mollica A.

J Med Chem. 2020 Mar 12;63(5):2673-2687. doi: 10.1021/acs.jmedchem.9b01963. Epub 2019 Dec 27.


Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening.

Poli G, Dimmito MP, Mollica A, Zengin G, Benyhe S, Zador F, Stefanucci A.

Molecules. 2019 Oct 27;24(21). pii: E3872. doi: 10.3390/molecules24213872.


Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: in Vivo and in Vitro Biological Profile.

Stefanucci A, Lei W, Pieretti S, Dimmito MP, Luisi G, Novellino E, Nowakowski M, Koźmiński W, Mirzaie S, Zengin G, Streicher JM, Mollica A.

ACS Med Chem Lett. 2019 Mar 8;10(4):450-456. doi: 10.1021/acsmedchemlett.8b00495. eCollection 2019 Apr 11.


On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity.

Stefanucci A, Lei W, Pieretti S, Novellino E, Dimmito MP, Marzoli F, Streicher JM, Mollica A.

Sci Rep. 2019 Apr 8;9(1):5771. doi: 10.1038/s41598-019-42289-5.


Anti-Oxidant and Tyrosinase Inhibitory In Vitro Activity of Amino Acids and Small Peptides: New Hints for the Multifaceted Treatment of Neurologic and Metabolic Disfunctions.

Luisi G, Stefanucci A, Zengin G, Dimmito MP, Mollica A.

Antioxidants (Basel). 2018 Dec 26;8(1). pii: E7. doi: 10.3390/antiox8010007.


Discovery of arginine-containing tripeptides as a new class of pancreatic lipase inhibitors.

Stefanucci A, Luisi G, Zengin G, Macedonio G, Dimmito MP, Novellino E, Mollica A.

Future Med Chem. 2019 Jan;11(1):5-19. doi: 10.4155/fmc-2018-0216. Epub 2018 Dec 11.


Biochemical and pharmacological investigation of novel nociceptin/OFQ analogues and N/OFQ-RYYRIK hybrid peptides.

Erdei AI, Borbély A, Magyar A, Szűcs E, Ötvös F, Gombos D, Al-Khrasani M, Stefanucci A, Dimmito MP, Luisi G, Mollica A, Benyhe S.

Peptides. 2019 Feb;112:106-113. doi: 10.1016/j.peptides.2018.11.010. Epub 2018 Dec 1.


Effects of Kisspeptin-10 on Hypothalamic Neuropeptides and Neurotransmitters Involved in Appetite Control.

Orlando G, Leone S, Ferrante C, Chiavaroli A, Mollica A, Stefanucci A, Macedonio G, Dimmito MP, Leporini L, Menghini L, Brunetti L, Recinella L.

Molecules. 2018 Nov 24;23(12). pii: E3071. doi: 10.3390/molecules23123071.


Effects of RVD-hemopressin (α) on feeding and body weight after standard or cafeteria diet in rats.

Leone S, Ferrante C, Recinella L, Chiavaroli A, Mollica A, Tömböly C, Stefanucci A, Dimmito MP, Dvorácskó S, Verratti V, De Petrocellis L, Orlando G, Brunetti L.

Neuropeptides. 2018 Dec;72:38-46. doi: 10.1016/j.npep.2018.10.002. Epub 2018 Oct 27.


Effects of central RVD-hemopressin(α) administration on anxiety, feeding behavior and hypothalamic neuromodulators in the rat.

Recinella L, Chiavaroli A, Ferrante C, Mollica A, Macedonio G, Stefanucci A, Dimmito MP, Dvorácskó S, Tömböly C, Brunetti L, Orlando G, Leone S.

Pharmacol Rep. 2018 Aug;70(4):650-657. doi: 10.1016/j.pharep.2018.01.010. Epub 2018 Feb 2.


Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides.

Stefanucci A, Angeli A, Dimmito MP, Luisi G, Del Prete S, Capasso C, Donald WA, Mollica A, Supuran CT.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):945-950. doi: 10.1080/14756366.2018.1468530.


Combinatorial peptide library screening for discovery of diverse α-glucosidase inhibitors using molecular dynamics simulations and binary QSAR models.

Mollica A, Zengin G, Durdagi S, Ekhteiari Salmas R, Macedonio G, Stefanucci A, Dimmito MP, Novellino E.

J Biomol Struct Dyn. 2019 Feb;37(3):726-740. doi: 10.1080/07391102.2018.1439403. Epub 2018 Feb 22.


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