Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 231

1.

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.

Indra R, Pompach P, Martínek V, Takácsová P, Vavrová K, Heger Z, Adam V, Eckschlager T, Kopečková K, Arlt VM, Stiborová M.

Int J Mol Sci. 2019 Jul 10;20(14). pii: E3392. doi: 10.3390/ijms20143392.

PMID:
31295928
Free Article
2.

Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid.

Jelaković B, Dika Ž, Arlt VM, Stiborova M, Pavlović NM, Nikolić J, Colet JM, Vanherweghem JL, Nortier JL.

Semin Nephrol. 2019 May;39(3):284-296. doi: 10.1016/j.semnephrol.2019.02.007. Review.

PMID:
31054628
3.

Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells.

Indra R, Černá T, Heger Z, Hraběta J, Wilhelm M, Dostálová S, Lengálová A, Martínková M, Adam V, Eckschlager T, Schmeiser HH, Arlt VM, Stiborová M.

Toxicology. 2019 May 1;419:40-54. doi: 10.1016/j.tox.2019.03.009. Epub 2019 Mar 23.

PMID:
30914192
4.

Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro.

Kolarik M, Indra R, Adam V, Heger Z, Kopeckova K, Arlt VM, Stiborova M.

Neuro Endocrinol Lett. 2019 Feb;39(7):515-524.

PMID:
30860683
5.

Prostate cancer-specific hallmarks of amino acids metabolism: Towards a paradigm of precision medicine.

Strmiska V, Michalek P, Eckschlager T, Stiborova M, Adam V, Krizkova S, Heger Z.

Biochim Biophys Acta Rev Cancer. 2019 Apr;1871(2):248-258. doi: 10.1016/j.bbcan.2019.01.001. Epub 2019 Jan 29. Review.

PMID:
30708041
6.

Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine.

Reed L, Indra R, Mrizova I, Moserova M, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM.

Toxicol Appl Pharmacol. 2019 Mar 1;366:64-74. doi: 10.1016/j.taap.2019.01.020. Epub 2019 Jan 25.

7.

Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe-Dnmts axis.

Strmiska V, Michalek P, Lackova Z, Guran R, Krizkova S, Vanickova L, Zitka O, Stiborova M, Eckschlager T, Klejdus B, Pacik D, Tvrdikova E, Keil C, Haase H, Adam V, Heger Z.

Mol Oncol. 2019 May;13(5):1002-1017. doi: 10.1002/1878-0261.12439. Epub 2019 Mar 9.

8.

Folic acid-mediated re-shuttling of ferritin receptor specificity towards a selective delivery of highly cytotoxic nickel(II) coordination compounds.

Tesarova B, Charousova M, Dostalova S, Bienko A, Kopel P, Kruszyński R, Hynek D, Michalek P, Eckschlager T, Stiborova M, Adam V, Heger Z.

Int J Biol Macromol. 2019 Apr 1;126:1099-1111. doi: 10.1016/j.ijbiomac.2018.12.128. Epub 2018 Dec 31.

PMID:
30605747
9.

Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin.

Dostalova S, Polanska H, Svobodova M, Balvan J, Krystofova O, Haddad Y, Krizkova S, Masarik M, Eckschlager T, Stiborova M, Heger Z, Adam V.

Sci Rep. 2018 Jun 11;8(1):8867. doi: 10.1038/s41598-018-26772-z.

10.

Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats.

Stiborová M, Dračínská H, Bořek-Dohalská L, Klusoňová Z, Holecová J, Martínková M, Schmeiser HH, Arlt VM.

Toxicology. 2018 May 1;400-401:48-56. doi: 10.1016/j.tox.2018.04.001. Epub 2018 Apr 9.

12.

The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells.

Willis AJ, Indra R, Wohak LE, Sozeri O, Feser K, Mrizova I, Phillips DH, Stiborova M, Arlt VM.

Toxicology. 2018 Apr 1;398-399:1-12. doi: 10.1016/j.tox.2018.02.006. Epub 2018 Feb 19.

13.

Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin.

Merlos Rodrigo MA, Dostalova S, Buchtelova H, Strmiska V, Michalek P, Krizkova S, Vicha A, Jencova P, Eckschlager T, Stiborova M, Heger Z, Adam V.

Oncotarget. 2017 Dec 16;9(4):4427-4439. doi: 10.18632/oncotarget.23333. eCollection 2018 Jan 12.

14.

Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.

Reed L, Mrizova I, Barta F, Indra R, Moserova M, Kopka K, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM.

Arch Toxicol. 2018 Apr;92(4):1625-1638. doi: 10.1007/s00204-018-2162-7. Epub 2018 Jan 24.

15.

Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers.

Baker SC, Arlt VM, Indra R, Joel M, Stiborová M, Eardley I, Ahmad N, Otto W, Burger M, Rubenwolf P, Phillips DH, Southgate J.

Mol Carcinog. 2018 May;57(5):606-618. doi: 10.1002/mc.22784. Epub 2018 Feb 1.

16.

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells.

Cerna T, Hrabeta J, Eckschlager T, Frei E, Schmeiser HH, Arlt VM, Stiborová M.

Int J Mol Sci. 2018 Jan 5;19(1). pii: E164. doi: 10.3390/ijms19010164.

17.

Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes.

Rodrigo MAM, Strmiska V, Horackova E, Buchtelova H, Michalek P, Stiborova M, Eckschlager T, Adam V, Heger Z.

Prostate. 2018 Feb;78(2):104-112. doi: 10.1002/pros.23450. Epub 2017 Nov 6.

PMID:
29105933
18.

Cytochrome b5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine.

Stiborová M, Indra R, Frei E, Kopečková K, Schmeiser HH, Eckschlager T, Adam V, Heger Z, Arlt VM, Martínek V.

Monatsh Chem. 2017;148(11):1983-1991. doi: 10.1007/s00706-017-1986-9. Epub 2017 Jul 4.

19.

Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches.

Martínek V, Bárta F, Hodek P, Frei E, Schmeiser HH, Arlt VM, Stiborová M.

Monatsh Chem. 2017;148(11):1971-1981. doi: 10.1007/s00706-017-2014-9. Epub 2017 Jul 26.

20.

Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems.

Stiborová M, Indra R, Moserová M, Bořek-Dohalská L, Hodek P, Frei E, Kopka K, Schmeiser HH, Arlt VM.

Monatsh Chem. 2017;148(11):1959-1969. doi: 10.1007/s00706-017-2002-0. Epub 2017 Jul 10.

Supplemental Content

Loading ...
Support Center