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Items: 17


Tubular bile duct structure mimicking bile duct morphogenesis for prospective in vitro liver metabolite recovery.

Rizki-Safitri A, Shinohara M, Tanaka M, Sakai Y.

J Biol Eng. 2020 Mar 19;14:11. doi: 10.1186/s13036-020-0230-z. eCollection 2020.


The bioprinting roadmap.

Sun W, Starly B, Daly AC, Burdick JA, Groll J, Skeldon G, Shu W, Sakai Y, Shinohara M, Nishikawa M, Jang J, Cho DW, Nie M, Takeuchi S, Ostrovidov S, Khademhosseini A, Kamm RD, Mironov V, Moroni L, Ozbolat IT.

Biofabrication. 2020 Feb 6;12(2):022002. doi: 10.1088/1758-5090/ab5158.


Boyden chamber-based compartmentalized tumor spheroid culture system to implement localized anticancer drug treatment.

Kaneda S, Kawada J, Shinohara M, Kumemura M, Ueno R, Kawamoto T, Suzuki K, Kim B, Ikeuchi Y, Sakai Y, Collard D, Fujita H, Fujii T.

Biomicrofluidics. 2019 Oct 24;13(5):054111. doi: 10.1063/1.5125650. eCollection 2019 Sep.


Endodermal differentiation of human induced pluripotent stem cells using simple dialysis culture system in suspension culture.

Shinohara M, Choi H, Ibuki M, Yabe SG, Okochi H, Miyajima A, Sakai Y.

Regen Ther. 2019 May 30;12:14-19. doi: 10.1016/j.reth.2019.05.004. eCollection 2019 Dec 15.


Organization of liver organoids using Raschig ring-like micro-scaffolds and triple co-culture: Toward modular assembly-based scalable liver tissue engineering.

Pang Y, Sutoko S, Wang Z, Horimoto Y, Montagne K, Horiguchi I, Shinohara M, Danoy M, Niino T, Sakai Y.

Med Eng Phys. 2020 Feb;76:69-78. doi: 10.1016/j.medengphy.2019.10.010. Epub 2019 Dec 26.


Improved Isolation of Mesenchymal Stem Cells Based on Interactions between N-Acetylglucosamine-Bearing Polymers and Cell-Surface Vimentin.

Ise H, Matsunaga K, Shinohara M, Sakai Y.

Stem Cells Int. 2019 Nov 11;2019:4341286. doi: 10.1155/2019/4341286. eCollection 2019.


Analysis of the transcription factors and their regulatory roles during a step-by-step differentiation of induced pluripotent stem cells into hepatocyte-like cells.

Tauran Y, Poulain S, Lereau-Bernier M, Danoy M, Shinohara M, Segard BD, Kato S, Kido T, Miyajima A, Sakai Y, Plessy C, Leclerc E.

Mol Omics. 2019 Dec 2;15(6):383-398. doi: 10.1039/c9mo00122k.


Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads.

Mihara H, Kugawa M, Sayo K, Tao F, Shinohara M, Nishikawa M, Sakai Y, Akama T, Kojima N.

Cells. 2019 May 31;8(6). pii: E525. doi: 10.3390/cells8060525.


Investigation of the hepatic respiration and liver zonation on rat hepatocytes using an integrated oxygen biosensor in a microscale device.

Matsumoto S, Safitri AR, Danoy M, Maekawa T, Kinoshita H, Shinohara M, Sakai Y, Fujii T, Leclerc E.

Biotechnol Prog. 2019 Sep;35(5):e2854. doi: 10.1002/btpr.2854. Epub 2019 Jun 12.


Efficient functional cyst formation of biliary epithelial cells using microwells for potential bile duct organisation in vitro.

Rizki-Safitri A, Shinohara M, Miura Y, Danoy M, Tanaka M, Miyajima A, Sakai Y.

Sci Rep. 2018 Jul 23;8(1):11086. doi: 10.1038/s41598-018-29464-w.


[Tissue engineering-based approaches to enhance physiological relevancy of cell-based assays].

Sakai Y, Shinohara M.

Nihon Yakurigaku Zasshi. 2018;151(2):56-61. doi: 10.1254/fpj.151.56. Japanese.


Alteration of pancreatic carcinoma and promyeloblastic cell adhesion in liver microvasculature by co-culture of hepatocytes, hepatic stellate cells and endothelial cells in a physiologically-relevant model.

Danoy M, Shinohara M, Rizki-Safitri A, Collard D, Senez V, Sakai Y.

Integr Biol (Camb). 2017 Apr 18;9(4):350-361. doi: 10.1039/c6ib00237d.


Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment.

Leclerc E, Kimura K, Shinohara M, Danoy M, Le Gall M, Kido T, Miyajima A, Fujii T, Sakai Y.

Genomics. 2017 Jan;109(1):16-26. doi: 10.1016/j.ygeno.2016.11.008. Epub 2016 Nov 29.


Production of Cisplatin-Incorporating Hyaluronan Nanogels via Chelating Ligand-Metal Coordination.

Ohta S, Hiramoto S, Amano Y, Sato M, Suzuki Y, Shinohara M, Emoto S, Yamaguchi H, Ishigami H, Sakai Y, Kitayama J, Ito T.

Bioconjug Chem. 2016 Mar 16;27(3):504-8. doi: 10.1021/acs.bioconjchem.5b00674. Epub 2016 Jan 21.


The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes.

Xiao W, Shinohara M, Komori K, Sakai Y, Matsui H, Osada T.

Biotechnol Prog. 2014 Nov-Dec;30(6):1401-10. doi: 10.1002/btpr.1954. Epub 2014 Aug 8.


Adhesion of pancreatic cancer cells in a liver-microvasculature mimicking coculture correlates with their propensity to form liver-specific metastasis in vivo.

Chowdhury MM, Danoy M, Rahman F, Shinohara M, Kaneda S, Shiba K, Fujita N, Fujii T, Sakai Y.

Biomed Res Int. 2014;2014:241571. doi: 10.1155/2014/241571. Epub 2014 May 11.


Combination of microwell structures and direct oxygenation enables efficient and size-regulated aggregate formation of an insulin-secreting pancreatic β-cell line.

Shinohara M, Kimura H, Montagne K, Komori K, Fujii T, Sakai Y.

Biotechnol Prog. 2014 Jan-Feb;30(1):178-87. doi: 10.1002/btpr.1837. Epub 2013 Dec 6.


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