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Items: 18


A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells.

Sommella E, Badolati N, Riccio G, Salviati E, Bottone S, Dentice M, Campiglia P, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2019 Jan 14;11(1). pii: E163. doi: 10.3390/nu11010163.


Fmoc-FF and hexapeptide-based multicomponent hydrogels as scaffold materials.

Diaferia C, Ghosh M, Sibillano T, Gallo E, Stornaiuolo M, Giannini C, Morelli G, Adler-Abramovich L, Accardo A.

Soft Matter. 2019 Jan 21;15(3):487-496. doi: 10.1039/c8sm02366b. Epub 2019 Jan 2.


Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation.

Riccio G, Sommella E, Badolati N, Salviati E, Bottone S, Campiglia P, Dentice M, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2018 Nov 20;10(11). pii: E1808. doi: 10.3390/nu10111808.


Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation.

Badolati N, Sommella E, Riccio G, Salviati E, Heintz D, Bottone S, Di Cicco E, Dentice M, Tenore G, Campiglia P, Stornaiuolo M, Novellino E.

Nutrients. 2018 Oct 2;10(10). pii: E1406. doi: 10.3390/nu10101406.


A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist.

Riccio G, Bottone S, La Regina G, Badolati N, Passacantilli S, Rossi GB, Accardo A, Dentice M, Silvestri R, Novellino E, Stornaiuolo M.

Biochemistry. 2018 Feb 6;57(5):839-851. doi: 10.1021/acs.biochem.7b01087. Epub 2018 Jan 19.


WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations.

Riccio G, Maisto M, Bottone S, Badolati N, Rossi GB, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2017 Nov 18;9(11). pii: E1262. doi: 10.3390/nu9111262.


Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.

Skronska-Wasek W, Mutze K, Baarsma HA, Bracke KR, Alsafadi HN, Lehmann M, Costa R, Stornaiuolo M, Novellino E, Brusselle GG, Wagner DE, Yildirim AÖ, Königshoff M.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):172-185. doi: 10.1164/rccm.201605-0904OC.


Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques.

Oliviero G, Stornaiuolo M, D'Atri V, Nici F, Yousif AM, D'Errico S, Piccialli G, Mayol L, Novellino E, Marinelli L, Grieco P, Carotenuto A, Noppen S, Liekens S, Balzarini J, Borbone N.

Anal Chem. 2016 Feb 16;88(4):2327-34. doi: 10.1021/acs.analchem.5b04268. Epub 2016 Feb 5.


Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments.

Stornaiuolo M, Bruno A, Botta L, La Regina G, Cosconati S, Silvestri R, Marinelli L, Novellino E.

Sci Rep. 2015 Oct 20;5:15453. doi: 10.1038/srep15453.


Pharmacological folding chaperones act as allosteric ligands of Frizzled4.

Generoso SF, Giustiniano M, La Regina G, Bottone S, Passacantilli S, Di Maro S, Cassese H, Bruno A, Mallardo M, Dentice M, Silvestri R, Marinelli L, Sarnataro D, Bonatti S, Novellino E, Stornaiuolo M.

Nat Chem Biol. 2015 Apr;11(4):280-6. doi: 10.1038/nchembio.1770. Epub 2015 Mar 9.


Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.

Stornaiuolo M, La Regina G, Passacantilli S, Grassia G, Coluccia A, La Pietra V, Giustiniano M, Cassese H, Di Maro S, Brancaccio D, Taliani S, Ialenti A, Silvestri R, Martini C, Novellino E, Marinelli L.

J Med Chem. 2015 Mar 12;58(5):2135-48. doi: 10.1021/jm501123r. Epub 2015 Feb 25.


Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay.

Bruno A, Lembo F, Novellino E, Stornaiuolo M, Marinelli L.

Sci Rep. 2014 Jan 20;4:3757. doi: 10.1038/srep03757.


A disorder-to-order structural transition in the COOH-tail of Fz4 determines misfolding of the L501fsX533-Fz4 mutant.

Lemma V, D'Agostino M, Caporaso MG, Mallardo M, Oliviero G, Stornaiuolo M, Bonatti S.

Sci Rep. 2013;3:2659. doi: 10.1038/srep02659.


The cytosolic chaperone α-crystallin B rescues folding and compartmentalization of misfolded multispan transmembrane proteins.

D'Agostino M, Lemma V, Chesi G, Stornaiuolo M, Cannata Serio M, D'Ambrosio C, Scaloni A, Polishchuk R, Bonatti S.

J Cell Sci. 2013 Sep 15;126(Pt 18):4160-72. doi: 10.1242/jcs.125443. Epub 2013 Jul 10.


Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

Stornaiuolo M, De Kloe GE, Rucktooa P, Fish A, van Elk R, Edink ES, Bertrand D, Smit AB, de Esch IJ, Sixma TK.

Nat Commun. 2013;4:1875. doi: 10.1038/ncomms2900.


Transient transfection coupled to baculovirus infection for rapid protein expression screening in insect cells.

Radner S, Celie PH, Fuchs K, Sieghart W, Sixma TK, Stornaiuolo M.

J Struct Biol. 2012 Jul;179(1):46-55. doi: 10.1016/j.jsb.2012.04.013. Epub 2012 May 2.


PrP(C) association with lipid rafts in the early secretory pathway stabilizes its cellular conformation.

Sarnataro D, Campana V, Paladino S, Stornaiuolo M, Nitsch L, Zurzolo C.

Mol Biol Cell. 2004 Sep;15(9):4031-42. Epub 2004 Jun 30.


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